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Q9RL69

- Q9RL69_STAAU

UniProt

Q9RL69 - Q9RL69_STAAU

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Protein
Submitted name:

Mrp protein

Gene

mrp

Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Names & Taxonomyi

Protein namesi
Submitted name:
Mrp proteinImported
Submitted name:
SasC/Mrp/FmtB intercellular aggregation domain proteinImported
Gene namesi
Name:mrpImported
ORF Names:DP18_2513Imported, X998_2136Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
  2. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

Family & Domainsi

Phylogenomic databases

OrthoDBiEOG6N3CNZ.

Family and domain databases

InterProiIPR011439. DUF1542.
IPR026359. SasC_Mrp_aggreg_dom.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF07564. DUF1542. 18 hits.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
TIGRFAMsiTIGR04263. SasC_Mrp_aggreg. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RL69-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MNLFRQQKFS IRKFNVGIFS ALIATVTFIS TNPTTASAAE QNQPAQNQPA
60 70 80 90 100
QPADANTQPN ANAGAQANPT AQPAAPANQG QPAVQPANQG GQANPAGGAA
110 120 130 140 150
QPNTQPAGQG NQADPNNAAQ AQPGNQATPA NQAGQGNNQA TPNNNATPAN
160 170 180 190 200
QTQPANAPAA AQPAAPVAAN AQTQDPNASN TGEGSINTTL TFDDPAISTD
210 220 230 240 250
ENRQDPTVTV TDKVNGYSLI NNGKIGFVNS ELRRSDMFDK NNPQNYQAKG
260 270 280 290 300
NVAALGRVNA NDSTDHGNFN GISKTVNVKP DSELIINFTT MQTNSKQGAT
310 320 330 340 350
NLVIKDAKKN TELATVNVAK TGTAHLFKVP TDADRLDLQF IPDNTAVADA
360 370 380 390 400
SRITTNKDGY KYYSFIDNVG LFSGSHLYVK NRDLAPKATN NKEYTINTEI
410 420 430 440 450
GNNGNFGASL KADQFKYEVT LPQGVTYVNN SLTTTFPNGN EDSTVLKNMT
460 470 480 490 500
VNYDQNANKV TFTSQGVTTA RGTHTKEVLF PDKSLKLSYK VNVANIDTPK
510 520 530 540 550
NIDFNEKLTY RTASDVVINN AQPEVTLTAD PFSVAVEMNK DALQQQVNSQ
560 570 580 590 600
VDNSHYTTAS IAEYNKLKQQ ADTILNEDAN HVKTANRASQ ADIDGLVTKL
610 620 630 640 650
QAALIDNQAA IAELDTKAQE KVTAAQQSKK VTQDEVAALV TKINNDKNNA
660 670 680 690 700
IAEINKQTTA QGVTTEKDNG IAVLEQDVIT PTVKPQAKQD IIQAVTTRKQ
710 720 730 740 750
QIKKSNASLQ DEKDVANDKI GKIETKAIKD IDAATTNAQV EAIKTKAIND
760 770 780 790 800
INQTTPATTA KAAALEEFDE VVQAQIDQAP LNPDTTNEEV AEAIERINAA
810 820 830 840 850
KVSGVKAIEA TTTAQDLERV KNEEISKIEN ITDSTQTKMD AYNEVKQAAT
860 870 880 890 900
ARKAQNATVS NATNEEVAEA DAAVDAAQKQ GLHDIQVVKS KQEVADTKSK
910 920 930 940 950
VLDKINAIQT QAKVKPAADT EVENAYNTRK QEIQNSNAST TEEKQAAYTE
960 970 980 990 1000
LDTKKQEART NLDAANTNSD VTTAKDNSIA AINQVQAATT KKSDAKAEIA
1010 1020 1030 1040 1050
QKASERKTAI EAMNDSTTEE QQAAKDKVDQ AVVTANADID NAAANNDVDN
1060 1070 1080 1090 1100
AKTTNEATIA AITPDANVKP AAKQAIADKV QAQETAIDGN NGSTTEEKAA
1110 1120 1130 1140 1150
AKQQVQTEKT TADAAIDAAH TNAEVEAAKK AAIAKIEAIQ PATTTKDNAK
1160 1170 1180 1190 1200
EAIATKANER KTAIAQTQDI TAEEIAAANA DVDNAVTQAN SNIEAANSQN
1210 1220 1230 1240 1250
DVDQAKTTGE NSIDQVTPTV NKKATARNEI TAILNNKLQE IQATPDATDE
1260 1270 1280 1290 1300
EKQAADAEAN TENGKANQAI SAATTNAQVD EAKANAEAAI NAVTPKVVKK
1310 1320 1330 1340 1350
QAAKDEIDQL QATQTNVINN DQNATTEEKE AAIQQLATAV TDAKNNITAA
1360 1370 1380 1390 1400
TDDNGVDQAK DAGKNSIQST QPATAVKSNA KNDVDQAVTT QNQAIDNTTG
1410 1420 1430 1440 1450
ATTEEKNAAK DLVLKAKEKA YQDILNAQTT NDVTQIKDQA VADIQGITAD
1460 1470 1480 1490 1500
TTIKDVAKDE LATKANEQKA LIAQTADATT EEKEQANQQV DAQLTQGNQN
1510 1520 1530 1540 1550
IENAQSIDDV NTAKDNAIQA IDPIQASTDV KTNARAELLT EMQNKITEIL
1560 1570 1580 1590 1600
NNNETTNEEK GNDIGPVRAA YEEGLNNINA ATTTGDVTTA KDTAVQKVQQ
1610 1620 1630 1640 1650
LHANPVKKPA GKKELDQAAA DKKTQIEQTP NASQQEINDA KQEVDTELNQ
1660 1670 1680 1690 1700
AKTNVDQSST NEYVDNAVKE GKAKINAVKT FSEYKKDALA KIEDAYNAKV
1710 1720 1730 1740 1750
NEADNSNAST SSEIAEAKQK LAELKQTADQ NVNQATSKDD IEVQIHNDLD
1760 1770 1780 1790 1800
NINDYTIPTG KKESATTDLY AYADQKKNNI SADTNATQDE KQQAIKQVDQ
1810 1820 1830 1840 1850
NVQTALESIN NGVDNGDVDD ALTQGKAAID AIQVDATVKP KANQAIEVKA
1860 1870 1880 1890 1900
EDTKESIDQS DQLTAEEKTE ALAMIKQITD QAKQGITDAT TTAEVEKAKA
1910 1920 1930 1940 1950
QGLEAFDNIQ IDSTEKQKAI EELETALDQI EAGVNVNADA TTEEKEAFTN
1960 1970 1980 1990 2000
ALEDILSKAT EDISDQTTNA EIATVKNSAL EQLKAQRINP EVKKNALEAI
2010 2020 2030 2040 2050
REVVNKQIEI IKNADADASA KEIARTDLGR YFDRFADKLD KTQTNAEVAE
2060 2070 2080 2090 2100
LQNVTIPAIE AIVPQNDPDA NDTNNGIDNN DATANSNANA TPENTGQPNV
2110 2120 2130 2140 2150
SETTANGKAD ASPTTPNNSD AATGETTATS ATDDANDKPQ ANNNSSVDAS
2160 2170 2180 2190 2200
TNSPTMDNDV TSKPEVESTN NGTTDKPVTE TDNATPAEST TNNNSTTTAT
2210 2220 2230 2240 2250
NENAPTGSTA TAPTTASTEA ASSADSKDNA SVNDSKQNAE VNNSAESQST
2260 2270 2280 2290 2300
NDKVAQPKSE NKAKAEKDGS DSTNQSMVES TTETLPSADI TEPNVPSNTS
2310 2320 2330 2340 2350
KDKEESTTNQ TDAGQLKSET NVASNEADKS PSKADTEVSN KPSTSASSEA
2360 2370 2380 2390 2400
KEKMTSTNLS QKDDTATADT NDTQKSVGSA ANNKATQNDG ANASPATVSN
2410 2420 2430 2440 2450
GSNSANQDML NVTNTDDHQA KTKSAQQGKV NKAKQQAKTL PDTGMSHNDD
2460 2470
LPYAELALGA GMAFLIRRFT KKDQQTEE
Length:2,478
Mass (Da):263,031
Last modified:May 1, 2000 - v1
Checksum:i6B9859A02D023C74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP007539 Genomic DNA. Translation: AHW66825.1.
Y09927 Genomic DNA. Translation: CAB55329.1.
JOVN01000001 Genomic DNA. Translation: KFL14522.1.
RefSeqiYP_186963.1. NC_002951.2.

Genome annotation databases

GeneIDi3237427.
KEGGisac:SACOL2150.
PATRICi19530565. VBIStaAur112458_2094.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP007539 Genomic DNA. Translation: AHW66825.1 .
Y09927 Genomic DNA. Translation: CAB55329.1 .
JOVN01000001 Genomic DNA. Translation: KFL14522.1 .
RefSeqi YP_186963.1. NC_002951.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3237427.
KEGGi sac:SACOL2150.
PATRICi 19530565. VBIStaAur112458_2094.

Phylogenomic databases

OrthoDBi EOG6N3CNZ.

Family and domain databases

InterProi IPR011439. DUF1542.
IPR026359. SasC_Mrp_aggreg_dom.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF07564. DUF1542. 18 hits.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR04263. SasC_Mrp_aggreg. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A phosphoglucomutase-like gene essential for the optimal expression of methicillin resistance in Staphylococcus aureus: molecular cloning and DNA sequencing."
    Wu S., de Lencastre H., Sali A., Tomasz A.
    Microb. Drug Resist. 2:277-286(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: COLImported.
  2. "The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase."
    Jolly L., Wu S.W., Van Heijenoort J., de Lencastre H., Mengin-Lecreulx D., Tomasz A.
    J. Bacteriol. 179:5321-5325(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: COLImported.
  3. "Mrp -- a new auxiliary gene essential for optimal expression of methicillin resistance in Staphylococcus aureus."
    Wu S., de Lencastre H.
    Microb. Drug Resist. 5:9-18(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: COLImported.
  4. Wu S.W.
    Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: COLImported.
  5. "Genome sequence of Staphylococcus aureus NRS 100."
    Sichtig H., Utter B., Tallon L.J., Deshong S.Lisa., Sengamalay N., Nagaraj S., McCracken C.L., Daugherty S.
    Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NRS 100Imported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CDC 73-57501Imported.

Entry informationi

Entry nameiQ9RL69_STAAU
AccessioniPrimary (citable) accession number: Q9RL69
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)