Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9RKU5

- ALLB_STRCO

UniProt

Q9RKU5 - ALLB_STRCO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Allantoinase

Gene

allB

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.UniRule annotation

Catalytic activityi

(S)-allantoin + H2O = allantoate.UniRule annotation

Cofactori

Binds 2 zinc ions per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi63 – 631Zinc 1UniRule annotation
Metal bindingi65 – 651Zinc 1UniRule annotation
Metal bindingi150 – 1501Zinc 1; via carbamate groupUniRule annotation
Metal bindingi150 – 1501Zinc 2; via carbamate groupUniRule annotation
Metal bindingi186 – 1861Zinc 2UniRule annotation
Metal bindingi238 – 2381Zinc 2UniRule annotation
Metal bindingi311 – 3111Zinc 1UniRule annotation

GO - Molecular functioni

  1. allantoinase activity Source: UniProtKB-HAMAP
  2. cobalt ion binding Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. allantoin catabolic process Source: UniProtKB-HAMAP
  2. purine nucleobase metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Purine metabolism

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00395; UER00653.

Names & Taxonomyi

Protein namesi
Recommended name:
AllantoinaseUniRule annotation (EC:3.5.2.5UniRule annotation)
Alternative name(s):
Allantoin-utilizing enzymeUniRule annotation
Gene namesi
Name:allBUniRule annotation
Ordered Locus Names:SCO6247
ORF Names:SCAH10.12, STAH10.12
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445AllantoinasePRO_0000165943Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei150 – 1501N6-carboxylysineUniRule annotation

Post-translational modificationi

Carbamylation allows a single lysine to coordinate two zinc ions.UniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi100226.SCO6247.

Structurei

3D structure databases

ProteinModelPortaliQ9RKU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DHOase family. Allantoinase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0044.
HOGENOMiHOG000219146.
InParanoidiQ9RKU5.
KOiK01466.
OMAiCSPWEGH.
OrthoDBiEOG6KHFW6.
PhylomeDBiQ9RKU5.

Family and domain databases

Gene3Di2.30.40.10. 1 hit.
HAMAPiMF_01645. Hydantoinase.
InterProiIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
TIGRFAMsiTIGR03178. allantoinase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RKU5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEAELVLRS TRVITPEGTR AASVAVTGEK ITAVLPYDAP VPAGARLEDV
60 70 80 90 100
GDHVVLPGLV DTHVHVNDPG RTEWEGFWTA TRAAAAGGIT TLVDMPLNSI
110 120 130 140 150
PPTTTVDNLR TKREVAADKA HIDVGFWGGA LPDNVKDLRP LHEAGVFGFK
160 170 180 190 200
AFLSPSGVDE FPHLDQEQLA RSLAEIAAFD GLLIVHAEDP HHLAAAPQQG
210 220 230 240 250
GPKYTHFLAS RPRDAEDTAI ATLLAQAKRF NARVHVLHLS SSDALPLIAE
260 270 280 290 300
ARADGVRVTV ETCPHYLTLT AEEVPDGASE FKCCPPIREA ANQDLLWQAL
310 320 330 340 350
ADGTIDCVVT DHSPSTADLK TDDFATAWGG IAGLQLSLPA MWTAARGRGL
360 370 380 390 400
GLEDVVRWMS ERTAALVGLD ARKGAIAPGH DADFAVLAPD ETFTVDPAAL
410 420 430 440
QHRNRVTAYA GKTLYGVVKS TWLRGERIVA DGAFTDPKGQ LLDRA
Length:445
Mass (Da):47,492
Last modified:May 1, 2000 - v1
Checksum:i75955C5F98632570
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939126 Genomic DNA. Translation: CAB60166.1.
RefSeqiNP_630347.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB60166; CAB60166; CAB60166.
GeneIDi1101688.
KEGGisco:SCO6247.
PATRICi23742428. VBIStrCoe124346_6361.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939126 Genomic DNA. Translation: CAB60166.1 .
RefSeqi NP_630347.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q9RKU5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO6247.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB60166 ; CAB60166 ; CAB60166 .
GeneIDi 1101688.
KEGGi sco:SCO6247.
PATRICi 23742428. VBIStrCoe124346_6361.

Phylogenomic databases

eggNOGi COG0044.
HOGENOMi HOG000219146.
InParanoidi Q9RKU5.
KOi K01466.
OMAi CSPWEGH.
OrthoDBi EOG6KHFW6.
PhylomeDBi Q9RKU5.

Enzyme and pathway databases

UniPathwayi UPA00395 ; UER00653 .

Family and domain databases

Gene3Di 2.30.40.10. 1 hit.
HAMAPi MF_01645. Hydantoinase.
InterProi IPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view ]
SUPFAMi SSF51338. SSF51338. 2 hits.
TIGRFAMsi TIGR03178. allantoinase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiALLB_STRCO
AccessioniPrimary (citable) accession number: Q9RKU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: October 29, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3