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Q9RKU5 (ALLB_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Allantoinase

EC=3.5.2.5
Alternative name(s):
Allantoin-utilizing enzyme
Gene names
Name:allB
Ordered Locus Names:SCO6247
ORF Names:SCAH10.12, STAH10.12
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring By similarity. HAMAP-Rule MF_01645

Catalytic activity

(S)-allantoin + H2O = allantoate. HAMAP-Rule MF_01645

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP-Rule MF_01645

Pathway

Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1. HAMAP-Rule MF_01645

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01645

Post-translational modification

Carbamylation allows a single lysine to coordinate two zinc ions By similarity. HAMAP-Rule MF_01645

Sequence similarities

Belongs to the DHOase family. Allantoinase subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Allantoinase HAMAP-Rule MF_01645
PRO_0000165943

Sites

Metal binding631Zinc 1 By similarity
Metal binding651Zinc 1 By similarity
Metal binding1501Zinc 1; via carbamate group By similarity
Metal binding1501Zinc 2; via carbamate group By similarity
Metal binding1861Zinc 2 By similarity
Metal binding2381Zinc 2 By similarity
Metal binding3111Zinc 1 By similarity

Amino acid modifications

Modified residue1501N6-carboxylysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RKU5 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 75955C5F98632570

FASTA44547,492
        10         20         30         40         50         60 
MSEAELVLRS TRVITPEGTR AASVAVTGEK ITAVLPYDAP VPAGARLEDV GDHVVLPGLV 

        70         80         90        100        110        120 
DTHVHVNDPG RTEWEGFWTA TRAAAAGGIT TLVDMPLNSI PPTTTVDNLR TKREVAADKA 

       130        140        150        160        170        180 
HIDVGFWGGA LPDNVKDLRP LHEAGVFGFK AFLSPSGVDE FPHLDQEQLA RSLAEIAAFD 

       190        200        210        220        230        240 
GLLIVHAEDP HHLAAAPQQG GPKYTHFLAS RPRDAEDTAI ATLLAQAKRF NARVHVLHLS 

       250        260        270        280        290        300 
SSDALPLIAE ARADGVRVTV ETCPHYLTLT AEEVPDGASE FKCCPPIREA ANQDLLWQAL 

       310        320        330        340        350        360 
ADGTIDCVVT DHSPSTADLK TDDFATAWGG IAGLQLSLPA MWTAARGRGL GLEDVVRWMS 

       370        380        390        400        410        420 
ERTAALVGLD ARKGAIAPGH DADFAVLAPD ETFTVDPAAL QHRNRVTAYA GKTLYGVVKS 

       430        440 
TWLRGERIVA DGAFTDPKGQ LLDRA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939126 Genomic DNA. Translation: CAB60166.1.
RefSeqNP_630347.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9RKU5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO6247.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB60166; CAB60166; CAB60166.
GeneID1101688.
KEGGsco:SCO6247.
PATRIC23742428. VBIStrCoe124346_6361.

Phylogenomic databases

eggNOGCOG0044.
HOGENOMHOG000219146.
KOK01466.
OMACSPWEGH.
OrthoDBEOG6KHFW6.
PhylomeDBQ9RKU5.

Enzyme and pathway databases

UniPathwayUPA00395; UER00653.

Family and domain databases

Gene3D2.30.40.10. 1 hit.
HAMAPMF_01645. Hydantoinase.
InterProIPR017593. Allantoinase.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
SUPFAMSSF51338. SSF51338. 2 hits.
TIGRFAMsTIGR03178. allantoinase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLB_STRCO
AccessionPrimary (citable) accession number: Q9RKU5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways