Q9RKU4 (ALLC_STRCO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable allantoicase
EC=3.5.3.4

Alternative name(s):
Allantoate amidinohydrolase

Gene names

Name:	alc
Ordered Locus Names:	SCO6248
ORF Names:	SCAH10.13, STAH10.13

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Allantoate + H2O = (S)-ureidoglycolate + urea. HAMAP MF_00813
Pathway	Nitrogen metabolism; (S)-allantoin degradation; (S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1. HAMAP MF_00813
Sequence similarities	Belongs to the allantoicase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	allantoicase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 376	376	Probable allantoicase HAMAP MF_00813		PRO_0000205929

Sequences

	Sequence		Length	Mass (Da)
	Q9RKU4 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 2247C0B2300C4A29	FASTA	376	41,208
	10 20 30 40 50 60 MTAQQNTSLA SFTGDAQPYG GGDPYADYRT ADLPFTQYAN LADRQLGAGV VAANDEFFAQ 70 80 90 100 110 120 RENLLVPEPA EFDPEHFGHK GKVMDGWETR RRRGVSAEQP WPTEEDHDWA LIRLGAPGVI 130 140 150 160 170 180 RGIVVDTAHF RGNYPQAVSV EGASVAGSPS PEELLADDVK WTTLVPRTPV GGHAANGFAV 190 200 210 220 230 240 SAEQRFTHLR LKQHPDGGIA RLRVYGEVVA DPAWLAALGT FDVVALENGG QVEDASNLFY 250 260 270 280 290 300 SPATNTIQPG RSRKMDDGWE TRRRRDKGND WIQYRLVDRS QIRAIEIDTA YLKGNSAGWA 310 320 330 340 350 360 SVSVKDGEAG EWREVLPRTR MQPDTNHRFV LPEAAVGTHA RVDIFPDGGI SRLRLFGSLT 370 EDGAARLAAR HQELGG

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939126 Genomic DNA. Translation: CAB60167.1.
RefSeq	NP_630348.1. NC_003888.3.
3D structure databases
ProteinModelPortal	Q9RKU4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1101689.
GenomeReviews	Gene locus SCO6248 in contig AL645882_GR.
KEGG	sco:SCO6248.
NMPDR	fig|100226.1.peg.6193.
PATRIC	23742430. VBIStrCoe124346_6362.
Phylogenomic databases
HOGENOM	HBG480577.
OMA	ELKSDDW.
PhylomeDB	Q9RKU4.
ProtClustDB	PRK13257.
Family and domain databases
HAMAP	MF_00813. Allantoicase. [Tree]
InterPro	IPR005164. Allantoicase. IPR015908. Allantoicase_dom. IPR008979. Galactose-bd-like. [Graphical view]
KO	K01477.
PANTHER	PTHR12045. Allantoicase. 1 hit.
Pfam	PF03561. Allantoicase. 2 hits. [Graphical view]
PIRSF	PIRSF016516. Allantoicase. 1 hit.
SUPFAM	SSF49785. Gal_bind_like. 2 hits.
TIGRFAMs	TIGR02961. Allantoicase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLC_STRCO

Accession

Primary (citable) accession number: Q9RKU4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program