Q9RKR2 (Q9RKR2_STRCO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Ordered Locus Names:

SCO2266

Organism

Streptomyces coelicolor

Taxonomic identifier

1902 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL CAB61712.1 Hydrolase Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9RKR2 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 94E1801801C03D32	FASTA	285	31,143
	10 20 30 40 50 60 MSGQSLLVPG ELSPTRSVPG NIRRPEYVGK PAPTPYTGPE VQTPETVEAM RVAGRIAARA 70 80 90 100 110 120 MEEAAKHIAP GVTTDALDRV AHEYMCDHGA YPSTLGYRGY PKSLCSSVNE VICHGIPDST 130 140 150 160 170 180 VLRDGDIVNL DVTAYIGGVH GDNNATYLVG EVDEESRLLV ERTRESLTRA IKAVKPGRQI 190 200 210 220 230 240 NIIGRVIESY AKRFGYGVVR DFTGHGINTS FHSGLIVPHY DSPHATTVIQ PGMTFTIEPM 250 260 270 280 LTLGTHEYDM WDDGWTVVTK DRRRTAQFEH TLVVTDSGAE ILTLP

References

[1]

"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)." Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A. , Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A. Nature 417:141-147(2002) [PubMed: 12000953] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-471 / A3(2) / M145.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL939112 Genomic DNA. Translation: CAB61712.1.
PIR	T50575.
RefSeq	NP_626514.1. NC_003888.3.
3D structure databases
HSSP	HSSP built from PDB template 1C24 based on UniProtKB P07906.
ProteinModelPortal	Q9RKR2.
SMR	Q9RKR2. Positions 4-283.
ModBase	Search...
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1097699.
GenomeReviews	Gene locus SCO2266 in contig AL645882_GR.
KEGG	sco:SCO2266.
NMPDR	fig|100226.1.peg.2231.
PATRIC	23734188. VBIStrCoe124346_2303.
Phylogenomic databases
HOGENOM	HBG299384.
OMA	YDMWDDG.
PhylomeDB	Q9RKR2.
ProtClustDB	PRK05716.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
PROSITE	PS00680. MAP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9RKR2_STRCO

Accession

Primary (citable) accession number: Q9RKR2

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)