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Q9RJZ6

- ALDH_STRCO

UniProt

Q9RJZ6 - ALDH_STRCO

Protein

Probable aldehyde dehydrogenase

Gene

SCO1174

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei263 – 2631By similarity
    Active sitei302 – 3021By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi219 – 2257NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable aldehyde dehydrogenase (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SCO1174
    ORF Names:SCG11A.05
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 507507Probable aldehyde dehydrogenasePRO_0000056464Add
    BLAST

    Proteomic databases

    PRIDEiQ9RJZ6.

    Interactioni

    Protein-protein interaction databases

    STRINGi100226.SCO1174.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9RJZ6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiRIEQNIE.
    OrthoDBiEOG6BS8QW.
    PhylomeDBiQ9RJZ6.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9RJZ6-1 [UniParc]FASTAAdd to Basket

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    MTRYAAPGTE GAIVSYQSRY DHFIGGEYVP PARGQYFENP SPVNGLPFTE    50
    IARGTADDVE RALDAAHEAA PGWGRTSVTE RSDILLKIAD RMEANLERLA 100
    VAESWENGKP VRETLAADIP LAIDHFRYFA GAVRAQEGSL GEIDDDTVAY 150
    HFHEPLGVVA QIIPWNFPIL MATWKLAPAL AAGNAVVLKP AEQTPASIHY 200
    WLSLVADLLP PGVLNVVNGF GVEAGKPLAS SPRVAKVAFT GETTTGRLIM 250
    QYASENIKPV TLELGGKSPN IFFEDVWARD DDFRDKALEG FTMFALNQGE 300
    VCTCPSRALV QRGVYAEFME AAVARTELIK PGHPLDTDTM IGAQASNDQL 350
    EKILSYLDIG RQEGAKVLTG GERIEHDGEL KGGYYVQPTI FEGHNRMRIF 400
    QEEIFGPVVS VTSFDDFDDA VKTANDTLYG LGAGVWTRDM NTAYRAGRAI 450
    QAGRVWTNCY HAYPAHAAFG GYKQSGIGRE NHKMMLEHYQ QTKNILCSYS 500
    PKKLGFF 507
    Length:507
    Mass (Da):55,674
    Last modified:May 1, 2000 - v1
    Checksum:i0110815B2D8F96DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939108 Genomic DNA. Translation: CAB61586.1.
    RefSeqiNP_625464.1. NC_003888.3.
    WP_011027628.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAB61586; CAB61586; CAB61586.
    GeneIDi1096597.
    KEGGisco:SCO1174.
    PATRICi23731898. VBIStrCoe124346_1172.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939108 Genomic DNA. Translation: CAB61586.1 .
    RefSeqi NP_625464.1. NC_003888.3.
    WP_011027628.1. NC_003888.3.

    3D structure databases

    ProteinModelPortali Q9RJZ6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO1174.

    Proteomic databases

    PRIDEi Q9RJZ6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB61586 ; CAB61586 ; CAB61586 .
    GeneIDi 1096597.
    KEGGi sco:SCO1174.
    PATRICi 23731898. VBIStrCoe124346_1172.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi RIEQNIE.
    OrthoDBi EOG6BS8QW.
    PhylomeDBi Q9RJZ6.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145.

    Entry informationi

    Entry nameiALDH_STRCO
    AccessioniPrimary (citable) accession number: Q9RJZ6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3