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Protein

Probable aldehyde dehydrogenase

Gene

SCO1174

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei263By similarity1
Active sitei302By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi219 – 225NADBy similarity7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Probable aldehyde dehydrogenase (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:SCO1174
ORF Names:SCG11A.05
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564641 – 507Probable aldehyde dehydrogenaseAdd BLAST507

Proteomic databases

PRIDEiQ9RJZ6.

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO1174.

Structurei

3D structure databases

ProteinModelPortaliQ9RJZ6.
SMRiQ9RJZ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26. Bacteria.
COG1012. LUCA.
HOGENOMiHOG000271505.
InParanoidiQ9RJZ6.
KOiK00138.
OMAiHGAAPGW.
OrthoDBiPOG091H09V0.
PhylomeDBiQ9RJZ6.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiView protein in InterPro
IPR016161. Ald_DH/histidinol_DH.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
PfamiView protein in Pfam
PF00171. Aldedh. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiView protein in PROSITE
PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RJZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRYAAPGTE GAIVSYQSRY DHFIGGEYVP PARGQYFENP SPVNGLPFTE
60 70 80 90 100
IARGTADDVE RALDAAHEAA PGWGRTSVTE RSDILLKIAD RMEANLERLA
110 120 130 140 150
VAESWENGKP VRETLAADIP LAIDHFRYFA GAVRAQEGSL GEIDDDTVAY
160 170 180 190 200
HFHEPLGVVA QIIPWNFPIL MATWKLAPAL AAGNAVVLKP AEQTPASIHY
210 220 230 240 250
WLSLVADLLP PGVLNVVNGF GVEAGKPLAS SPRVAKVAFT GETTTGRLIM
260 270 280 290 300
QYASENIKPV TLELGGKSPN IFFEDVWARD DDFRDKALEG FTMFALNQGE
310 320 330 340 350
VCTCPSRALV QRGVYAEFME AAVARTELIK PGHPLDTDTM IGAQASNDQL
360 370 380 390 400
EKILSYLDIG RQEGAKVLTG GERIEHDGEL KGGYYVQPTI FEGHNRMRIF
410 420 430 440 450
QEEIFGPVVS VTSFDDFDDA VKTANDTLYG LGAGVWTRDM NTAYRAGRAI
460 470 480 490 500
QAGRVWTNCY HAYPAHAAFG GYKQSGIGRE NHKMMLEHYQ QTKNILCSYS

PKKLGFF
Length:507
Mass (Da):55,674
Last modified:May 1, 2000 - v1
Checksum:i0110815B2D8F96DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939108 Genomic DNA. Translation: CAB61586.1.
RefSeqiNP_625464.1. NC_003888.3.
WP_011027628.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB61586; CAB61586; CAB61586.
GeneIDi1096597.
KEGGisco:SCO1174.
PATRICifig|100226.15.peg.1172.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiALDH_STRCO
AccessioniPrimary (citable) accession number: Q9RJZ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: June 7, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families