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Q9RJZ6 (ALDH_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable aldehyde dehydrogenase

EC=1.2.1.3
Gene names
Ordered Locus Names:SCO1174
ORF Names:SCG11A.05
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Protein attributes

Sequence length507 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 507507Probable aldehyde dehydrogenase
PRO_0000056464

Regions

Nucleotide binding219 – 2257NAD By similarity

Sites

Active site2631 By similarity
Active site3021 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RJZ6 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 0110815B2D8F96DD

FASTA50755,674
        10         20         30         40         50         60 
MTRYAAPGTE GAIVSYQSRY DHFIGGEYVP PARGQYFENP SPVNGLPFTE IARGTADDVE 

        70         80         90        100        110        120 
RALDAAHEAA PGWGRTSVTE RSDILLKIAD RMEANLERLA VAESWENGKP VRETLAADIP 

       130        140        150        160        170        180 
LAIDHFRYFA GAVRAQEGSL GEIDDDTVAY HFHEPLGVVA QIIPWNFPIL MATWKLAPAL 

       190        200        210        220        230        240 
AAGNAVVLKP AEQTPASIHY WLSLVADLLP PGVLNVVNGF GVEAGKPLAS SPRVAKVAFT 

       250        260        270        280        290        300 
GETTTGRLIM QYASENIKPV TLELGGKSPN IFFEDVWARD DDFRDKALEG FTMFALNQGE 

       310        320        330        340        350        360 
VCTCPSRALV QRGVYAEFME AAVARTELIK PGHPLDTDTM IGAQASNDQL EKILSYLDIG 

       370        380        390        400        410        420 
RQEGAKVLTG GERIEHDGEL KGGYYVQPTI FEGHNRMRIF QEEIFGPVVS VTSFDDFDDA 

       430        440        450        460        470        480 
VKTANDTLYG LGAGVWTRDM NTAYRAGRAI QAGRVWTNCY HAYPAHAAFG GYKQSGIGRE 

       490        500 
NHKMMLEHYQ QTKNILCSYS PKKLGFF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939108 Genomic DNA. Translation: CAB61586.1.
RefSeqNP_625464.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9RJZ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO1174.

Proteomic databases

PRIDEQ9RJZ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB61586; CAB61586; CAB61586.
GeneID1096597.
KEGGsco:SCO1174.
PATRIC23731898. VBIStrCoe124346_1172.

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHOG000271505.
KOK00128.
OMARIEQNIE.
OrthoDBEOG6BS8QW.
PhylomeDBQ9RJZ6.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALDH_STRCO
AccessionPrimary (citable) accession number: Q9RJZ6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families