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Q9RJS6 (PPNK1_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1
Short name=Poly(P)/ATP NAD kinase 1
EC=2.7.1.23
Gene names
Name:ppnK1
Ordered Locus Names:SCO0410
ORF Names:SCF51.09c
OrganismStreptomyces coelicolor
Taxonomic identifier1902 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Sequence caution

The sequence CAB59707.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 363363Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361
PRO_0000229699

Sequences

Sequence LengthMass (Da)Tools
Q9RJS6 [UniParc].

Last modified April 4, 2006. Version 2.
Checksum: 3BE603B1286D310C

FASTA36338,412
        10         20         30         40         50         60 
MTIERVGLVV HGGREGAAEA AREVREWCDE NAVACTDIDV WSDTGRHSAR EEVDAAGDPD 

        70         80         90        100        110        120 
LVVTLGGDGT FLRGARLAAE NDALILGVDL GRVGFLTEVP APAVRSALDA VRDGGLEPES 

       130        140        150        160        170        180 
RMLLTLRASR LLEIPAEMEA LLRYGRGPLL PPPRVRTDCE SGDEWGIALN VTALNDVVLE 

       190        200        210        220        230        240 
KLSRDRQISV GVYIAGRLLA SYSADALLVA TPTGSTAYSF AAGGPVVSPR AEALVFTAVA 

       250        260        270        280        290        300 
PHMTFDRSVV TAPDEPVGLR ILERSGRAAV SIDGQLRGVL DPGDWLGVYA APRRLRAVRL 

       310        320        330        340        350        360 
GPMDFYGRLR ERMRLTDAPA AVADGTPAPL WPVSTPPPGD LAHLALPVPG AEGASGDLLR 


EQS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL939105 Genomic DNA. Translation: CAB59707.1. Different initiation.
RefSeqNP_624731.1. NC_003888.3.

3D structure databases

ProteinModelPortalQ9RJS6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1095833.
GenomeReviewsGene locus SCO0410 in contig AL645882_GR.
KEGGsco:SCO0410.
NMPDRfig|100226.1.peg.384.
PATRIC23730328. VBIStrCoe124346_0386.

Phylogenomic databases

HOGENOMHBG713904.
PhylomeDBQ9RJS6.
ProtClustDBCLSK220390.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 2 hits.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK1_STRCO
AccessionPrimary (citable) accession number: Q9RJS6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: January 25, 2012
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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