Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Protein family/group databases

TCDBi2.A.64.2.2. the twin arginine targeting (tat) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:SCO1632Imported
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Imported
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 51HelicalUniRule annotationAdd BLAST20
Transmembranei99 – 120HelicalUniRule annotationAdd BLAST22
Transmembranei132 – 154HelicalUniRule annotationAdd BLAST23
Transmembranei181 – 202HelicalUniRule annotationAdd BLAST22
Transmembranei214 – 232HelicalUniRule annotationAdd BLAST19
Transmembranei238 – 260HelicalUniRule annotationAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi100226.SCO1632.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
InParanoidiQ9RJ69.
KOiK03118.
OMAiFPFVVDF.
OrthoDBiPOG091H02DA.
PhylomeDBiQ9RJ69.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiView protein in InterPro
IPR002033. TatC.
PANTHERiPTHR30371. PTHR30371. 1 hit.
PfamiView protein in Pfam
PF00902. TatC. 1 hit.
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RJ69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKPARNKEK DPEGRMPLAE HLRELRNRLA KALLAIVVVT VVAAFFYQWI
60 70 80 90 100
INALTDPILQ SIGCEKSFAE LAQSEAGSEP CAQITINGLL GPFTLALKVS
110 120 130 140 150
LTAGVVLASP VWLYQLWAFV APGLHRNEKK YAYAFVATGA PLFLAGAYFA
160 170 180 190 200
YAVLPTSAKV LIEFTPNDVD NLLPLDELLD LVTRMVVVFG LSFELPLLLV
210 220 230 240 250
MLNFTGVLTG KRMLGWWRAM IMGITLFAAI ATPSTDPLTM IMLAGPIWVL
260 270 280 290 300
YFAAVVVSLL NDRRKARLEA LEPDDDEASD LDLTPEDIGE VEPVTTARAL
310
PEQATKDRVN GYDDVT
Length:316
Mass (Da):34,663
Last modified:May 1, 2000 - v1
Checksum:iED6A6C7662ED5F85
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939109 Genomic DNA. Translation: CAB59485.1.
RefSeqiNP_625907.1. NC_003888.3.
WP_003977194.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB59485; CAB59485; CAB59485.
GeneIDi1097063.
29662875.
KEGGisco:SCO1632.
PATRICi23732866. VBIStrCoe124346_1647.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL939109 Genomic DNA. Translation: CAB59485.1.
RefSeqiNP_625907.1. NC_003888.3.
WP_003977194.1. NC_003888.3.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO1632.

Protein family/group databases

TCDBi2.A.64.2.2. the twin arginine targeting (tat) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB59485; CAB59485; CAB59485.
GeneIDi1097063.
29662875.
KEGGisco:SCO1632.
PATRICi23732866. VBIStrCoe124346_1647.

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
InParanoidiQ9RJ69.
KOiK03118.
OMAiFPFVVDF.
OrthoDBiPOG091H02DA.
PhylomeDBiQ9RJ69.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiView protein in InterPro
IPR002033. TatC.
PANTHERiPTHR30371. PTHR30371. 1 hit.
PfamiView protein in Pfam
PF00902. TatC. 1 hit.
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ9RJ69_STRCO
AccessioniPrimary (citable) accession number: Q9RJ69
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: March 15, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.