Reviewed, UniProtKB/Swiss-Prot Q9RHG2 (ARAA_MYCSM)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:

araA

Organism

Mycobacterium smegmatis

Taxonomic identifier

1772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	L-arabinose isomerase HAMAP MF_00519		PRO_0000198390
Sites
	Metal binding	306	1	Manganese By similarity
	Metal binding	333	1	Manganese By similarity
	Metal binding	350	1	Manganese By similarity
	Metal binding	449	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9RHG2-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: FD2CFFE85A2ED960	FASTA	501	54,955
	10 20 30 40 50 60 MAEHFTDEEI WFVTGSQSLY GQEILDQVAE QSRALAERLD ASADLPVAVR WKPVVTTSEA 70 80 90 100 110 120 ILDVLRDASS SPQCVGVITW MHTFSPAKMW IRGLSALQKP MLHLHTQFGV EIPWDTIDMD 130 140 150 160 170 180 FMNLNQAAHG DREFGYIQTR LSVPRTTVAG HVGDPRTTAR IGSWMRAALG AAELRSLRIA 190 200 210 220 230 240 RFGDNMRDVA VTEGDKVEAE SHFGVSVNTY SVNDLAKAVY DVSDPEIDKL VQEYEDTYAV 250 260 270 280 290 300 AEELRRGGER HASLREGARI ELGLRHFLAD GFGAFTTNFE DLGDLRQLPG LAVQRLMADG 310 320 330 340 350 360 FGFGAEGDWK TSAMVRTVKT MGVGLPGGTS FMEDYTYDLT PGSERILGAH MLEVCPSIAG 370 380 390 400 410 420 QTPSLEVHPL GIGNREDPVR LRFTAAPGSG VVLGICDMGS RFRLVANHVT VVEPSAPLPN 430 440 450 460 470 480 LPVACAVWEP EPSWSTSTEA WLMAGGPHHT VLTTAVSPTT LDDFATITGT ELLQIDQHTT 490 500 PREFQREMRW NAVYHHIAAG L

References

[1]	Soda A., Takata G., Izumori K. Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SMDU.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB036736 Genomic DNA. Translation: BAA89428.1. AB038527 Genomic DNA. Translation: BAA92526.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.3.1.4. 259.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_MYCSM

Accession

Primary (citable) accession number: Q9RHG2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	May 1, 2000
Last modified:	September 22, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)