Q9RGF1 (Q9RGF1_CAMJE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha-2,3-sialyltransferase EMBL AAF13495.1

Gene names

Name:

cst-I EMBL AAF13495.1

Organism

Campylobacter jejuni EMBL AAF13495.1

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	430 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Glycosyltransferase EMBL AAF13495.1 Transferase
Technical term	3D-structure PDB 2P2V PDB 2P56
Gene Ontology (GO)
Molecular function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9RGF1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 1D03B6797169425C	FASTA	430	50,396
	10 20 30 40 50 60 MTRTRMENEL IVSKNMQNII IAGNGPSLKN INYKRLPREY DVFRCNQFYF EDKYYLGKKI 70 80 90 100 110 120 KAVFFNPGVF LQQYHTAKQL ILKNEYEIKN IFCSTFNLPF IESNDFLHQF YNFFPDAKLG 130 140 150 160 170 180 YEVIENLKEF YAYIKYNEIY FNKRITSGVY MCAIAIALGY KTIYLCGIDF YEGDVIYPFE 190 200 210 220 230 240 AMSTNIKTIF PGIKDFKPSN CHSKEYDIEA LKLLKSIYKV NIYALCDDSI LANHFPLSIN 250 260 270 280 290 300 INNNFTLENK HNNSINDILL TDNTPGVSFY KNQLKADNKI MLNFYNILHS KDNLIKFLNK 310 320 330 340 350 360 EIAVLKKQTT QRAKARIQNH LSYKLGQALI INSKSVLGFL SLPFIILSIV ISHKQEQKAY 370 380 390 400 410 420 KFKVKKNPNL ALPPLETYPD YNEALKEKEC FTYKLGEEFI KAGKNWYGEG YIKFIFKDVP 430 RLKREFEKGE

References

[1]	"Biosynthesis of ganglioside mimics in Campylobacter jejuni OH4384. Identification of the glycosyltransferase genes, enzymatic synthesis of model compounds, and characterization of nanomole amounts by 600-MHz (1)H and (13)C NMR analysis." Gilbert M., Brisson J.-R., Karwaski M.-F., Michniewicz J., Cunningham A.-M., Wu Y., Young N.M., Wakarchuk W.W. J. Biol. Chem. 275:3896-3906(2000) [PubMed: 10660542] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: OH4384 EMBL AAF13495.1.
[2]	"Lipopolysaccharide .alpha.-2,3 sialyltransferase of campylobacter." Gilbert M., Wakarchuk W.W. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: OH4384 EMBL AAF13495.1.
[3]	"Structural analysis of the alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni in apo and substrate-analogue bound forms." Chiu C.P., Lairson L.L., Gilbert M., Wakarchuk W.W., Withers S.G., Strynadka N.C. Biochemistry 46:7196-7204(2007) [PubMed: 17518445] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 1-285.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF130466 Genomic DNA. Translation: AAF13495.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2P2V	X-ray	1.85	A	1-285	[»]
2P56	X-ray	2.20	A	1-285	[»]

ProteinModelPortal

Q9RGF1.

SMR

Q9RGF1. Positions 5-281.

ModBase

Search...

Protein family/group databases

CAZy

GT42. Glycosyltransferase Family 42.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR009251. A-2_3-sialyltransferase.
[Graphical view]

Gene3D

G3DSA:3.90.1480.10. A-2_3-sialyltransferase. 1 hit.

Pfam

PF06002. CST-I. 1 hit.
[Graphical view]

SUPFAM

SSF102414. A-2_3-sialyltransferase. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9RGF1_CAMJE

Accession

Primary (citable) accession number: Q9RGF1

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	January 11, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)