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Reviewed, UniProtKB/Swiss-Prot Q9RG22 (ACP_RHILE)

Last modified September 22, 2009. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Acyl carrier protein acpP
      Short name=ACP
Gene names
Name: acpP
OrganismRhizobium leguminosarum
Taxonomic identifier384 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Carrier of the growing fatty acid chain in fatty acid biosynthesis. HAMAP MF_01217

Pathway

Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217

Subcellular location

Cytoplasm By similarity.

Post-translational modification

4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group. HAMAP MF_01217

Sequence similarities

Contains 1 acyl carrier domain.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Cellular componentCytoplasm
   LigandPhosphopantetheine
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionacyl carrier activity

Inferred from electronic annotation. Source: HAMAP

cofactor binding

Inferred from electronic annotation. Source: InterPro

phosphopantetheine binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 7877Acyl carrier protein acpP HAMAP MF_01217
PRO_0000180174

Amino acid modifications

Modified residue371O-(pantetheine 4'-phosphoryl)serine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9RG22-1 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 1F8AF26196409ACB

FASTA788,368
        10         20         30         40         50         60 
MSDIAERVKK IVIDHLGVDA DKVVESASFI DDLGADSLDT VELVMAFEEE FGVEIPDDAA 

        70 
DSILTVGDAV KFIEKAQA 

« Hide

References

[1]"Expression and purification of four different rhizobial acyl carrier proteins."
Lopez-Lara I.M., Geiger O.
Microbiology 146:839-849(2000) [PubMed: 10784042] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LPR5045.

Cross-references

Sequence databases

AF159243 Genomic DNA. Translation: AAF24179.1.

3D structure databases

HSSPHSSP built from PDB template 1ACP based on UniProtKB P02901.
ModBaseSearch...

Family and domain databases

HAMAPMF_01217.
[Tree]
InterProIPR003231. Acyl_carrier.
IPR009081. Acyl_carrier_prot-like.
IPR006163. Phsphopanteth_bd.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomPD000887. Acyl_carrier. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00517. acyl_carrier. 1 hit.
PROSITEPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACP_RHILE
AccessionPrimary (citable) accession number: Q9RG22
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 23, 2007
Last modified: September 22, 2009
This is version 53 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents