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Protein

Membrane protein insertase YidC 1

Gene

yidC1

Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Transport

Protein family/group databases

TCDBi2.A.9.3.5. the membrane protein insertase (yidc/alb3/oxa1) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidC 1UniRule annotation
Alternative name(s):
Foldase YidC 1UniRule annotation
Membrane integrase YidC 1UniRule annotation
Membrane protein YidC 1UniRule annotation
Gene namesi
Name:yidC1UniRule annotation
Ordered Locus Names:BH4064
OrganismiBacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Taxonomic identifieri272558 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001258 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 55HelicalUniRule annotationAdd BLAST21
Transmembranei59 – 79HelicalUniRule annotationAdd BLAST21
Transmembranei129 – 149HelicalUniRule annotationAdd BLAST21
Transmembranei160 – 180HelicalUniRule annotationAdd BLAST21
Transmembranei205 – 225HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20UniRule annotationAdd BLAST20
ChainiPRO_000002037521 – 257Membrane protein insertase YidC 1Add BLAST237

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi21N-palmitoyl cysteineUniRule annotation1
Lipidationi21S-diacylglycerol cysteineUniRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRIDEiQ9RCA5.

Interactioni

Protein-protein interaction databases

STRINGi272558.BH4064.

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.UniRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0706. LUCA.
HOGENOMiHOG000009662.
KOiK03217.
OMAiHAITRTS.
OrthoDBiPOG091H00BE.

Family and domain databases

HAMAPiMF_01811. YidC_type2. 1 hit.
InterProiIPR028055. Membr_insert_YidC/Oxa1_C.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
IPR023060. YidC/YidC1/YidC2_Firmicutes.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03592. yidC_oxa1_cterm. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9RCA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRKFGMAAM LVSILLLMTG CFNVNEPINA QSEGIWDSYF VYPLSWLMIY
60 70 80 90 100
FANAFNGSFG LAIIVVTLLI RLLILPLMIK QLKSTRAMQA LQPEMQALRE
110 120 130 140 150
KYSAKDQRTQ QKLQQETMAL FQKHGVNPLA GCFPVLIQMP ILLAFYHAIM
160 170 180 190 200
RTREIGDEHF LWFVLNQPDP ILLPIIAGIT TFLQQKMMMV TDNPQMKVLL
210 220 230 240 250
YVMPVMILVF AMFLPSSLAL YWVIGNLFMI LQTYFITGPN VGAKKVAADV

KVGGKKK
Length:257
Mass (Da):29,223
Last modified:May 1, 2000 - v1
Checksum:i223AF5D688F161FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013492 Genomic DNA. Translation: BAA82682.1.
BA000004 Genomic DNA. Translation: BAB07783.1.
PIRiH84157.

Genome annotation databases

EnsemblBacteriaiBAB07783; BAB07783; BAB07783.
KEGGibha:BH4064.
PATRICi18945466. VBIBacHal18977_4226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013492 Genomic DNA. Translation: BAA82682.1.
BA000004 Genomic DNA. Translation: BAB07783.1.
PIRiH84157.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272558.BH4064.

Protein family/group databases

TCDBi2.A.9.3.5. the membrane protein insertase (yidc/alb3/oxa1) family.

Proteomic databases

PRIDEiQ9RCA5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB07783; BAB07783; BAB07783.
KEGGibha:BH4064.
PATRICi18945466. VBIBacHal18977_4226.

Phylogenomic databases

eggNOGiCOG0706. LUCA.
HOGENOMiHOG000009662.
KOiK03217.
OMAiHAITRTS.
OrthoDBiPOG091H00BE.

Family and domain databases

HAMAPiMF_01811. YidC_type2. 1 hit.
InterProiIPR028055. Membr_insert_YidC/Oxa1_C.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
IPR023060. YidC/YidC1/YidC2_Firmicutes.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03592. yidC_oxa1_cterm. 1 hit.
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYIDC1_BACHD
AccessioniPrimary (citable) accession number: Q9RCA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: May 1, 2000
Last modified: November 2, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.