Q9RC80 (KCY_BACHD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	BH1634

Organism

Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) [Complete proteome] [HAMAP]

Taxonomic identifier

272558 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.
Sequence caution	The sequence BAA83919.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 222	222	Cytidylate kinase HAMAP MF_00238		PRO_0000131877
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9RC80 [UniParc]. Last modified December 1, 2000. Version 2. Checksum: 4668F92AB691305B	FASTA	222	24,862
	10 20 30 40 50 60 MKKMNIAIDG PAGAGKSTVA KQVAQALSFL YIDTGAMYRA LTYAAIEHHV SPDDEASLKS 70 80 90 100 110 120 LLDSIEIKLV DEQSKTRVYV NNTDVTDQVR TEEVTKTVSL VSSHGQVRKE MVRQQRLLAE 130 140 150 160 170 180 GTNCVLDGRD IGTYVLPNAE LKFFLTATVE ERARRRYEEN IQKGFKQSLE QLIKDIASRD 190 200 210 220 EFDSNRSFAP LRKAEDAIEI DTTSLSISEV TQTIIGYVKE RV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis." Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K. Nucleic Acids Res. 28:4317-4331(2000) [PubMed: 11058132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
[2]	"Genetic analysis of the chromosome of alkaliphilic Bacillus halodurans C-125." Takami H., Takaki Y., Nakasone K., Sakiyama T., Maeno G., Sasaki R., Hirama C., Fuji F., Masui N. Extremophiles 3:227-233(1999) [PubMed: 10484179] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-168. Strain: ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000004 Genomic DNA. Translation: BAB05353.1. AB024552 Genomic DNA. Translation: BAA83919.1. Different initiation.
PIR	B83854.
RefSeq	NP_242500.1. NC_002570.2.
3D structure databases
ProteinModelPortal	Q9RC80.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000052876; EBBACP00000051515; EBBACG00000052867.
GeneID	892560.
GenomeReviews	Gene locus BH1634 in contig BA000004_GR.
KEGG	bha:BH1634.
NMPDR	fig|272558.1.peg.1634.
PATRIC	18940384. VBIBacHal18977_1705.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000002974.
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	Q9RC80.
Enzyme and pathway databases
BioCyc	BHAL272558:BH1634-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_BACHD

Accession

Primary (citable) accession number: Q9RC80
Secondary accession number(s): Q9KCD8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	January 25, 2012
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program