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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei52 – 521NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-589-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Fjoh_0570
OrganismiFlavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / UW101) (Cytophaga johnsonae)
Taxonomic identifieri376686 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000006694 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229tRNA pseudouridine synthase BPRO_0000121826Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi376686.Fjoh_0570.

Structurei

3D structure databases

ProteinModelPortaliQ9RB36.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231223.
KOiK03177.
OMAiHEFEITR.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RB36-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPEEYLEGQ VLLIDKPLKW SSFQAVNKLK YLLINKVGLP KKFKIGHAGT
60 70 80 90 100
LDPLATGLLL ICTGKFTKKI SELQGQAKEY TGTFYIGATT PSYDLETEID
110 120 130 140 150
QTFPTEHINE VLIHETVKQF LGEIDQKPPI FSAIKKDGVR LYEHARAGES
160 170 180 190 200
IEIESRKTTI HEFEITRIAL PEIDFRVVCS KGTYIRSLAY DFGKAMNSGS
210 220
HLTVLRRTKI GDYDVKNAID ITLFEESLQ
Length:229
Mass (Da):25,872
Last modified:May 1, 2000 - v1
Checksum:iCFDA675657B8AC74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF169967 Genomic DNA. Translation: AAD50463.1.
CP000685 Genomic DNA. Translation: ABQ03605.1.
RefSeqiWP_012022661.1. NC_009441.1.

Genome annotation databases

EnsemblBacteriaiABQ03605; ABQ03605; Fjoh_0570.
KEGGifjo:Fjoh_0570.
PATRICi21895403. VBIFlaJoh53613_0588.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF169967 Genomic DNA. Translation: AAD50463.1.
CP000685 Genomic DNA. Translation: ABQ03605.1.
RefSeqiWP_012022661.1. NC_009441.1.

3D structure databases

ProteinModelPortaliQ9RB36.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi376686.Fjoh_0570.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABQ03605; ABQ03605; Fjoh_0570.
KEGGifjo:Fjoh_0570.
PATRICi21895403. VBIFlaJoh53613_0588.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231223.
KOiK03177.
OMAiHEFEITR.
OrthoDBiPOG091H02G9.

Enzyme and pathway databases

BioCyciFJOH376686:GIXN-589-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_FLAJ1
AccessioniPrimary (citable) accession number: Q9RB36
Secondary accession number(s): A5FMG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.