Q9RAE4 (GLND_RHILV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:

glnD

Organism

Rhizobium leguminosarum bv. viciae

Taxonomic identifier

387 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium › Rhizobium leguminosarum

Protein attributes

Sequence length	944 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.
Sequence caution	The sequence AAF17352.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Nitrogen fixation
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 944	944	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192758

Sequences

	Sequence		Length	Mass (Da)
	Q9RAE4 [UniParc]. Last modified December 8, 2000. Version 2. Checksum: B164E74FF9E6DF2E	FASTA	944	106,218
	10 20 30 40 50 60 MRDLDFTNIL DVELLQKQCD AVAEANRNRP DVLRADLLAV LKKASTEGRQ KAREALMADG 70 80 90 100 110 120 GGLNCAYRIS WLQDQITTVL YNFATAHIFP QQKDKFAVTA VGGYGRDTLA PGSDIDLLFL 130 140 150 160 170 180 FLPRPAEETH KAVEFMLYVL WDMGFKVGHA TRTVEECIAL SKSDMTIRTA ILEMRYICGL 190 200 210 220 230 240 QRLETELETR FDKEIVTGTG PEFIAAKLAE RDERHRKAGD TRYLVEPNVK EGKGGLRDLH 250 260 270 280 290 300 TLFWISKYYY HVRDQAELVK LGVLSKHEYR LLEKADDFLW AVRCHMHFLT GKAEERLSFD 310 320 330 340 350 360 IQREIAEAFG YHTRPGLSAV ERFMKHYFLV AKDVGDLTRI LCAALEDQQA KSIPGLTGVI 370 380 390 400 410 420 SRFTHRNRKI AGSVEFVEDR GRIALADPEV FKRDPVNIIR LFHVADINGL EFHPDALKRV 430 440 450 460 470 480 TRSLALIDNA LRENDEANRL FMSILTSKRD PALILRRMNE AGVLGRFIPE FGKIVAMMQF 490 500 510 520 530 540 NMYHHYTVDE HLIRTVDILS EIDKGRAEDL HPLANKLMPG IEDREALYVA VLLHDIAKGR 550 560 570 580 590 600 QEDHSIAGAR VARKLCVRFG LSQKQTEIVV WLIEEHLTMS MVAQTRDLTD RKTITDFADR 610 620 630 640 650 660 VQSLDRLKML LILTICDIRA VGPGVWNGWK GQLLRTLYYE TELLLAGGFS EVSRKERANA 670 680 690 700 710 720 AAEALHSALA DWSQKDRNTY TKLHYQPYLL SVPLEDQIRH AHFIRQADKA GQALATMVRT 730 740 750 760 770 780 DSFHAITEIT VLSPDHPRLL AVIAGACAAA GANIVDAQIF TTSDGRALDT IHVSREFTDD 790 800 810 820 830 840 ADELRRAATI GRMIEDVLSG RKRLPEVIAT RARNRKKSKA FVIPPSVNIT NSLSNKFTVI 850 860 870 880 890 900 EVECLDRPGL LSEITAVLSD LSLDIQSARI TTFGEKVIDT FYVTDLVGQK ISGDSKRANI 910 920 930 940 TARMKAVMAE EEDELRERMP SGIIAPAATA RTPPASEKKA GSPI

References

[1]	"Structural and functional analysis of the Rhizobium leguminosarum bv. viciae glnD gene coding for a putative uridylyltransferase/uridylyl-removing enzyme." Schlueter A., Noehlen M., Priefer U.B. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF155830 Genomic DNA. Translation: AAF17352.1. Different initiation.
3D structure databases
ProteinModelPortal	Q9RAE4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_RHILV

Accession

Primary (citable) accession number: Q9RAE4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 8, 2000
Last sequence update:	December 8, 2000
Last modified:	April 3, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program