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Protein

Probable nitrate/nitrite antiporter NarK1

Gene

narK1

Organism
Thermus thermophilus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the transport of nitrate and nitrite.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAntiport, Nitrate assimilation, Transport

Protein family/group databases

TCDBi2.A.1.8.8. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Probable nitrate/nitrite antiporter NarK1Curated
Gene namesi
Name:narK11 Publication
Synonyms:narKImported
OrganismiThermus thermophilus
Taxonomic identifieri274 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Transmembranei142 – 164HelicalSequence analysisAdd BLAST23
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Transmembranei255 – 275HelicalSequence analysisAdd BLAST21
Transmembranei298 – 318HelicalSequence analysisAdd BLAST21
Transmembranei329 – 349HelicalSequence analysisAdd BLAST21
Transmembranei368 – 388HelicalSequence analysisAdd BLAST21
Transmembranei401 – 421HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mutation has minor effects on the ability to grow anaerobically. In contrast, narK1/narK2 double mutant is unable to grow anaerobically.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004398591 – 443Probable nitrate/nitrite antiporter NarK1Add BLAST443

Structurei

3D structure databases

ProteinModelPortaliQ9RA46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR011701. MFS.
IPR020846. MFS_dom.
PfamiView protein in Pfam
PF07690. MFS_1. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiView protein in PROSITE
PS50850. MFS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9RA46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIHDPAQLEK ERPDRLRVLW LSTLAFTLMF AAWLMFGVLG VPIRKEFGLS
60 70 80 90 100
DVQLSWISAL AILNGSLWRL LAGILADRYG GRLVFTLMLF FTAIPAYLVS
110 120 130 140 150
RAGSYEELLL YAFLVGFAGN SFSVGIAWNS AWFPKDQQGF ALGVFGAGNV
160 170 180 190 200
GASVTKFIGP ALIASVPASG YLGGLIPGGW RFIPFLYAVL LVLMGFVLWF
210 220 230 240 250
GTPRKDKRPG QGRPFLDMLK PLRYVRVWRF SLYYVVVFGA YVALSAWLPK
260 270 280 290 300
YYVDVFGLPL HEAALLTALF IFPASLLRPV GGYLSDRFGA RRIMYWTFGI
310 320 330 340 350
ILLASGVLMM PEGHIVLYTK QGAKEVMQFT MGVELFTLLV FLIGVGMGIG
360 370 380 390 400
KAAVYKHIPT YFPQDVGAVG GLVGMLGALG GFFLPPLFAY AQAWTGLPQM
410 420 430 440
TFFVLFLLAA ISFLWMHLTV LKLLQQEAQH LKNDFELKGD RPC
Length:443
Mass (Da):49,095
Last modified:May 16, 2012 - v2
Checksum:i040632F0AF680BDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10124 Genomic DNA. Translation: CAB65479.2.

Similar proteinsi

Entry informationi

Entry nameiNARK1_THETH
AccessioniPrimary (citable) accession number: Q9RA46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2017
Last sequence update: May 16, 2012
Last modified: June 7, 2017
This is version 59 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families