Q9R6X1 (ATKB_ANASL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Potassium-transporting ATPase B chain
EC=3.6.3.12

Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chain
Potassium-binding and translocating subunit B
Potassium-translocating ATPase B chain

Gene names

Name:

kdpB

Organism

Anabaena sp. (strain L31)

Taxonomic identifier

29412 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	701 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions By similarity. HAMAP MF_00285
Catalytic activity	ATP + H2O + K+(Out) = ADP + phosphate + K+(In). HAMAP MF_00285
Subcellular location	Cell inner membrane; Multi-pass membrane protein Probable HAMAP MF_00285.
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Metal-binding Nucleotide-binding Potassium
Molecular function	Hydrolase
PTM	Phosphoprotein
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW magnesium ion binding Inferred from electronic annotation. Source: InterPro potassium-transporting ATPase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 701	701	Potassium-transporting ATPase B chain HAMAP MF_00285		PRO_0000046109
Regions
	Topological domain	1 – 49	49	Cytoplasmic Potential
	Transmembrane	50 – 72	23	Helical; Potential
	Topological domain	73 – 86	14	Periplasmic Potential
	Transmembrane	87 – 106	20	Helical; Potential
	Topological domain	107 – 243	137	Cytoplasmic Potential
	Transmembrane	244 – 266	23	Helical; Potential
	Topological domain	267 – 275	9	Periplasmic Potential
	Transmembrane	276 – 298	23	Helical; Potential
	Topological domain	299 – 594	296	Cytoplasmic Potential
	Transmembrane	595 – 617	23	Helical; Potential
	Topological domain	618 – 631	14	Periplasmic Potential
	Transmembrane	632 – 654	23	Helical; Potential
	Topological domain	655 – 673	19	Cytoplasmic Potential
	Transmembrane	674 – 696	23	Helical; Potential
	Topological domain	697 – 701	5	Periplasmic Potential
Sites
	Active site	329	1	4-aspartylphosphate intermediate By similarity
	Metal binding	539	1	Magnesium By similarity
	Metal binding	543	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9R6X1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 46F702E976708119	FASTA	701	74,359
	10 20 30 40 50 60 MNPDAPTPKN KSSRSRPSDR PQARKKAKIK TKGIYLRAIG DAFVKLNPKS AIRNPVMFLV 70 80 90 100 110 120 WVGTIITLSV TIEPNLFGTT QQKNPQLFNG ILTGILFFTV WFANFAEAVA EGRGKAQADT 130 140 150 160 170 180 LRSTKSETLA KLLSPDGKIT DVPSTSLKQG DTVYVVAGDV IPADGEVIMG VASVDESAIT 190 200 210 220 230 240 GESAPVLKES GSDIASSVTG GTRIISDELI VRVTADPGKG FIDRMIALVE GAERTKTPNE 250 260 270 280 290 300 VALTVLLAVL SLVFLFVVAT LPVFAYYADT PINVPILVAL LVALIPTTIG GLLSAIGIAG 310 320 330 340 350 360 MDRVAQFNVI ATSGRAVEAC GDVNTLVLDK TGTITLGNRL AEEFIPINGH SIEQVASVAW 370 380 390 400 410 420 VASVFDDTPE GKSIVRLAEK LGIRYDLDPN QAQGVEFSAK TRMSGTNLPG GREARKGAVG 430 440 450 460 470 480 AIKGFVRSRN GRITPELDVA YEQVSQQGGT PLAVCLDNEI YGVIYLKDIV KSGIRERFDQ 490 500 510 520 530 540 LRRMGVRTIM LTGDNRITAS VIAQEAGVDD FIAEATPEDK ISVIQREQAQ GKLVAMTGDG 550 560 570 580 590 600 TNDAPALAQA NVGVAMNTGT QAAKEAANMV DLDSDPTKLI DIVSIGKQLL ITRGALTTFS 610 620 630 640 650 660 LANDIAKYFA IIPVIFASAN LQSLNVMNLT STNSAVLSAL IYNALIIPAL IPLALKGVQF 670 680 690 700 RPLTANQLLQ RNILIYGLGG VIAPFIAIKL IDVLITLVGL A

References

[1]	"The kdp operon of the heterocystous nitrogen-fixing cyanobacterium Anabaena sp. strain L-31." Ballal A.D., Gassel M., Schleussinger E., Rajaram H., Apte S.K., Altendorf K. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: L-31.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF213466 Genomic DNA. Translation: AAF19987.1.
PIR	T46846.
3D structure databases
ProteinModelPortal	Q9R6X1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
HAMAP	MF_00285. KdpB. [Tree]
InterPro	IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. IPR006391. K-transp_ATPase_bsu. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
PANTHER	PTHR24093:SF27. PTHR24093:SF27. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 2 hits. TIGR01497. KdpB. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATKB_ANASL

Accession

Primary (citable) accession number: Q9R6X1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 8, 2000
Last sequence update:	May 1, 2000
Last modified:	December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program