Unreviewed, UniProtKB/TrEMBL Q9R435 (Q9R435_KLEPN)

Names and origin

Protein names

Submitted name:
    Extended spectrum beta-lactamase EMBL AAB84239.1
Submitted name:
    Extended-spectrum TEM-type beta-lactamase variant, TEM-52 EMBL CAA73933.1

Gene names

Name:

blaTEM-52 EMBL AAB84239.1

Encoded on

Plasmid pKK50-2 Ref.1 EMBL AAB84239.1

Organism

Klebsiella pneumoniae EMBL AAB84239.1

Taxonomic identifier

573 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Molecular function	Hydrolase Spearmint SPM001466
Technical term	Plasmid EMBL AAB84239.1
Gene Ontology (GO)
Biological process	beta-lactam antibiotic catabolic process Inferred from electronic annotation. Source: InterPro response to antibiotic Inferred from electronic annotation. Source: InterPro
Molecular function	beta-lactamase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9R435-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 13717ACCB58F6FB6	FASTA	286	31,514
	10 20 30 40 50 60 MSIQHFRVAL IPFFAAFCLP VFAHPETLVK VKDAEDQLGA RVGYIELDLN SGKILESFRP 70 80 90 100 110 120 EERFPMMSTF KVLLCGAVLS RVDAGQEQLG RRIHYSQNDL VKYSPVTEKH LTDGMTVREL 130 140 150 160 170 180 CSAAITMSDN TAANLLLTTI GGPKELTAFL HNMGDHVTRL DRWEPELNEA IPNDERDTTT 190 200 210 220 230 240 PAAMATTLRK LLTGELLTLA SRQQLIDWME ADKVAGPLLR SALPAGWFIA DKSGASERGS 250 260 270 280 RGIIAALGPD GKPSRIVVIY TTGSQATMDE RNRQIAEIGA SLIKHW

References

[1]	"Molecular Evolution of blaTEM of Extended Spectrum of beta-lactamase (ESBL) in Klebsiella pneumoniae isolated in Korea." Cho D.T., Shin H.S. Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: KMK107 EMBL AAB84239.1.
[2]	"A novel extended-spectrum TEM-type beta-lactamase (TEM-52) associated with decreased susceptibility to moxalactam in Klebsiella pneumoniae." Poyart C., Mugnier P., Quesne G., Berche P., Trieu-Cuot P. Antimicrob. Agents Chemother. 42:108-113(1998) [PubMed: 9449269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AF027199 Genomic DNA. Translation: AAB84239.1.
Y13612 Genomic DNA. Translation: CAA73933.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1HTZ	X-ray	2.40	A/B/C/D/E/F	24-286	[»]

ModBase

Search...

Family and domain databases

InterPro

IPR012338. B-lactamase-typ_transpept_fold.
IPR001466. Beta_lactamase-related.
IPR000871. Beta_lactamase_A/D.
[Graphical view]

Pfam

PF00144. Beta-lactamase. 1 hit.
[Graphical view]

PRINTS

PR00118. BLACTAMASEA.

PROSITE

PS00146. BETA_LACTAMASE_A. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9R435_KLEPN

Accession

Primary (citable) accession number: Q9R435

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)