Unreviewed, UniProtKB/TrEMBL Q9R2C9 (Q9R2C9_RAT)

Names and origin

Protein names

Submitted name:
    Interleukin-5 EMBL CAA09587.1

Gene names

Name:	Il5 RGD 2900
Synonyms:	IL-5 EMBL CAA09587.1

Organism

Rattus norvegicus (Rat) EMBL CAA09587.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	132 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	Signal EMBL CAA09587.1
Gene Ontology (GO)
Biological process	cytokine-mediated signaling pathway Inferred from direct assay. Source: RGD immune response Inferred from electronic annotation. Source: InterPro inflammatory response Inferred from expression pattern. Source: RGD positive regulation of B cell proliferation Inferred from direct assay. Source: RGD positive regulation of JAK-STAT cascade Inferred from mutant phenotype. Source: RGD positive regulation of eosinophil differentiation Inferred from direct assay. Source: RGD positive regulation of peptidyl-tyrosine phosphorylation Inferred from electronic annotation. Source: Compara
Cellular component	extracellular space Inferred from electronic annotation. Source: Compara soluble fraction Inferred from direct assay. Source: RGD
Molecular function	cytokine activity Inferred from direct assay. Source: RGD interleukin-5 receptor binding Inferred from direct assay. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 17	17	Potential EMBL CAA09587.1
	Chain	18 – 132	115	interleukin-5 EMBL CAA09587.1		PRO_5000064545

Sequences

	Sequence		Length	Mass (Da)
	Q9R2C9-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 814A87CB4C04702B	FASTA	132	15,191
	10 20 30 40 50 60 MRMLLCLNVL TLSCVWAIAM EIPMSTVVKE TLIQLSTHRA LLTSNETMRL PVPTHKNHQL 70 80 90 100 110 120 CIGEIFQGLD ILKNQTVRGG TVEIPFQNLS LIKKYIDGQK EKCGEERRKT RHFLDYLQEF 130 LGVMSTEWAM EV

References

[1]	"Cloning, expression of rat IL-5 and production of neutralizing antiserum: comparative study of IL-5 activity expressed in E.coli and baculovirus system." Pierrot C. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Lou M EMBL CAA09587.1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ011299 mRNA. Translation: CAA09587.1.
IPI	IPI00197557.
RefSeq	NP_068606.1.
UniGene	Rn.44227
3D structure databases
HSSP	HSSP built from PDB template 1HUL based on UniProtKB P05113.
SMR	Q9R2C9. Positions 22-128.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9R2C9.
Genome annotation databases
Ensembl	ENSRNOT00000010729; ENSRNOP00000010729; ENSRNOG00000008111; Rattus norvegicus. [Genome view]
GeneID	24497.
KEGG	rno:24497.
Organism-specific databases
CTD	24497.
Phylogenomic databases
HOVERGEN	Q9R2C9.
Gene expression databases
ArrayExpress	Q9R2C9.
Genevestigator	Q9R2C9.
Family and domain databases
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR000186. Interleukin_5. [Graphical view]
PANTHER	PTHR10525. Interleukin_5. 1 hit.
Pfam	PF02025. IL5. 1 hit. [Graphical view]
PRINTS	PR00432. INTERLEUKIN5.
ProDom	PD006721. Interleukin_5. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...
Other Resources
NextBio	603491.

Entry information

Entry name

Q9R2C9_RAT

Accession

Primary (citable) accession number: Q9R2C9

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)