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Q9R2B2

- Q9R2B2_MOUSE

UniProt

Q9R2B2 - Q9R2B2_MOUSE

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Protein
Submitted name: Cdc42/Rac effector kinase
Gene
Paka
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. protein serine/threonine kinase activity Source: Ensembl

GO - Biological processi

  1. actin cytoskeleton reorganization Source: Ensembl
  2. branching morphogenesis of an epithelial tube Source: Ensembl
  3. cellular response to insulin stimulus Source: Ensembl
  4. negative regulation of cell proliferation involved in contact inhibition Source: Ensembl
  5. neuron projection morphogenesis Source: Ensembl
  6. positive regulation of JUN kinase activity Source: Ensembl
  7. positive regulation of intracellular estrogen receptor signaling pathway Source: Ensembl
  8. positive regulation of peptidyl-serine phosphorylation Source: Ensembl
  9. positive regulation of stress fiber assembly Source: Ensembl
  10. protein autophosphorylation Source: Ensembl
  11. response to hypoxia Source: Ensembl
  12. wound healing Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

ReactomeiREACT_188530. FCERI mediated MAPK activation.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_215461. Signal transduction by L1.
REACT_225768. Generation of second messenger molecules.

Names & Taxonomyi

Protein namesi
Submitted name:
Cdc42/Rac effector kinaseImported
Gene namesi
Name:PakaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: Ensembl
  2. Z disc Source: Ensembl
  3. axon Source: Ensembl
  4. cytosol Source: Ensembl
  5. dendrite Source: Ensembl
  6. intercalated disc Source: Ensembl
  7. nuclear membrane Source: Ensembl
  8. plasma membrane Source: Ensembl
  9. protein complex Source: Ensembl
  10. ruffle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ9R2B2.
BgeeiQ9R2B2.
GenevestigatoriQ9R2B2.

Family & Domainsi

Phylogenomic databases

InParanoidiQ9R2B2.

Sequencei

Sequence statusi: Fragment.

Q9R2B2-1 [UniParc]FASTAAdd to Basket

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IQDKPPAPPM RNTSTMIGAG SKDTGTLNHG SKPLPPNPEE KKKKDRFYRS   50
ILPGDK 56
Length:56
Mass (Da):6,144
Last modified:May 1, 2000 - v1
Checksum:iD92E7F3D2AB4D21F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei56 – 561Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ133881 Genomic DNA. Translation: CAB41618.1.
UniGeneiMm.260227.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ133881 Genomic DNA. Translation: CAB41618.1 .
UniGenei Mm.260227.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

InParanoidi Q9R2B2.

Enzyme and pathway databases

Reactomei REACT_188530. FCERI mediated MAPK activation.
REACT_198374. Regulation of actin dynamics for phagocytic cup formation.
REACT_215461. Signal transduction by L1.
REACT_225768. Generation of second messenger molecules.

Gene expression databases

ArrayExpressi Q9R2B2.
Bgeei Q9R2B2.
Genevestigatori Q9R2B2.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon."
    Pittoggi C., Renzi L., Zaccagnini G., Cimini D., Degrassi F., Giordano R., Magnano A.R., Lorenzini R., Lavia P., Spadafora C.
    J. Cell Sci. 112:3537-3548(1999)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CD1Imported.
    Tissue: Cauda epididymisImported.

Entry informationi

Entry nameiQ9R2B2_MOUSE
AccessioniPrimary (citable) accession number: Q9R2B2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 3, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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