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Protein
Submitted name:

Cdc42/Rac effector kinase

Gene

Paka

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

ReactomeiREACT_271763. DSCAM interactions.
REACT_278281. Ephrin signaling.
REACT_307441. Sema3A PAK dependent Axon repulsion.
REACT_313804. EPHB-mediated forward signaling.
REACT_314186. FCERI mediated MAPK activation.
REACT_314817. CD28 dependent Vav1 pathway.
REACT_321965. VEGFR2 mediated vascular permeability.
REACT_334692. Generation of second messenger molecules.
REACT_344463. Regulation of actin dynamics for phagocytic cup formation.
REACT_353319. Signal transduction by L1.
REACT_359280. RHO GTPases activate PAKs.
REACT_360524. CD209 (DC-SIGN) signaling.

Names & Taxonomyi

Protein namesi
Submitted name:
Cdc42/Rac effector kinaseImported
Gene namesi
Name:PakaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Expressioni

Gene expression databases

BgeeiQ9R2B2.
ExpressionAtlasiQ9R2B2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033040.

Sequencei

Sequence statusi: Fragment.

Q9R2B2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IQDKPPAPPM RNTSTMIGAG SKDTGTLNHG SKPLPPNPEE KKKKDRFYRS

ILPGDK
Length:56
Mass (Da):6,144
Last modified:May 1, 2000 - v1
Checksum:iD92E7F3D2AB4D21F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei56 – 561Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ133881 Genomic DNA. Translation: CAB41618.1.
UniGeneiMm.260227.

Genome annotation databases

UCSCiuc009iju.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ133881 Genomic DNA. Translation: CAB41618.1.
UniGeneiMm.260227.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033040.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc009iju.1. mouse.

Enzyme and pathway databases

ReactomeiREACT_271763. DSCAM interactions.
REACT_278281. Ephrin signaling.
REACT_307441. Sema3A PAK dependent Axon repulsion.
REACT_313804. EPHB-mediated forward signaling.
REACT_314186. FCERI mediated MAPK activation.
REACT_314817. CD28 dependent Vav1 pathway.
REACT_321965. VEGFR2 mediated vascular permeability.
REACT_334692. Generation of second messenger molecules.
REACT_344463. Regulation of actin dynamics for phagocytic cup formation.
REACT_353319. Signal transduction by L1.
REACT_359280. RHO GTPases activate PAKs.
REACT_360524. CD209 (DC-SIGN) signaling.

Gene expression databases

BgeeiQ9R2B2.
ExpressionAtlasiQ9R2B2. baseline and differential.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon."
    Pittoggi C., Renzi L., Zaccagnini G., Cimini D., Degrassi F., Giordano R., Magnano A.R., Lorenzini R., Lavia P., Spadafora C.
    J. Cell Sci. 112:3537-3548(1999)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CD1Imported.
    Tissue: Cauda epididymisImported.

Entry informationi

Entry nameiQ9R2B2_MOUSE
AccessioniPrimary (citable) accession number: Q9R2B2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 22, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.