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Protein
Submitted name:

Fibroblast growth factor receptor 2

Gene

Fgfr2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • fibroblast growth factor-activated receptor activity Source: RGD
  • fibroblast growth factor binding Source: RGD

GO - Biological processi

  • cellular response to fibroblast growth factor stimulus Source: RGD
  • cellular response to retinoic acid Source: RGD
  • cellular response to transforming growth factor beta stimulus Source: RGD
  • embryonic cranial skeleton morphogenesis Source: InterPro
  • endochondral bone growth Source: RGD
  • epithelial to mesenchymal transition Source: RGD
  • fibroblast growth factor receptor signaling pathway Source: RGD
  • mesodermal cell differentiation Source: RGD
  • negative regulation of epithelial cell proliferation Source: RGD
  • positive regulation of smooth muscle cell proliferation Source: RGD
  • response to ethanol Source: RGD
  • response to lipopolysaccharide Source: RGD
  • wound healing Source: RGD

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Fibroblast growth factor receptor 2Imported
Submitted name:
Fibroblast growth factor receptor-2Imported
Gene namesi
Name:Fgfr2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2611. Fgfr2.

Subcellular locationi

GO - Cellular componenti

  • cell surface Source: RGD
  • cytoplasm Source: RGD
  • nucleus Source: RGD

Expressioni

Gene expression databases

BgeeiENSRNOG00000016374.

Interactioni

GO - Molecular functioni

  • fibroblast growth factor binding Source: RGD

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 46I-setInterPro annotationAdd BLAST40

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR028175. FGF_rcpt_2.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
PANTHERiPTHR24416:SF468. PTHR24416:SF468. 1 hit.
PfamiView protein in Pfam
PF07679. I-set. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9R2A0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
AAGVNTTDKE IEVLYIRNVT FEDAGEYTCL AGNSIGISFH SAWLTVLP
Length:48
Mass (Da):5,188
Last modified:May 1, 2000 - v1
Checksum:i70B9F2AA9DC87C38
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei48Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF456422 Genomic DNA. Translation: AAL77412.1.
D83495 Genomic DNA. Translation: BAA77279.1.
UniGeneiRn.12732.

Genome annotation databases

UCSCiRGD:2611. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9R2A0_RAT
AccessioniPrimary (citable) accession number: Q9R2A0
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: June 7, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)