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Protein
Submitted name:

Protein Mlnr

Gene

Mlnr

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • thyrotropin-releasing hormone receptor activity Source: RGD

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Protein MlnrImported
Submitted name:
Thyrotropin releasing hormone receptor 2Imported
Submitted name:
Thyrotropin-releasing hormone receptor 2Imported
Gene namesi
Name:MlnrImported
Synonyms:TRH-R2Imported, Trhr2Imported
ORF Names:rCG_51576Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi621262. Mlnr.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 48HelicalSequence analysisAdd BLAST26
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21
Transmembranei100 – 122HelicalSequence analysisAdd BLAST23
Transmembranei142 – 161HelicalSequence analysisAdd BLAST20
Transmembranei181 – 208HelicalSequence analysisAdd BLAST28
Transmembranei249 – 265HelicalSequence analysisAdd BLAST17
Transmembranei285 – 308HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • neuronal cell body Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3875.

Expressioni

Gene expression databases

BgeeiENSRNOG00000012789.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017317.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST267

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOVERGENiHBG007549.
KOiK04282.
OMAiIYGRAGC.
OrthoDBiEOG091G08BE.
TreeFamiTF326170.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9R297-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGPSNVSLI HGDTTLGLPE YKVVSVFLVL LVCTLGIVGN AMVILVVLTS
60 70 80 90 100
RDMHTPTNCY LVSLALADLL VLLAAGLPNV SDSLVGHWIY GRAGCLGITY
110 120 130 140 150
FQYLGINVSS FSILAFTVER YIAICHPLRA QTVCTVARAK RIIAGIWGVT
160 170 180 190 200
SLYCLLWFFL VDLNVRDNQR LECGYKVPRG LYLPIYLLDF AVFFIGPLLV
210 220 230 240 250
TLVLYGLIGR ILFQSPLSQE AWQKERQPHG QSEAAPGNCS RAKSSRKQAT
260 270 280 290 300
RMLAVVVLLF AVLWTPYRTL VLLNSFVAQP FLDPWVLLFC RTCVYTNSAV
310 320 330 340 350
NPVVYSLMSQ KFRAAFLKLC WCRAAGPQRR AARVLTSNYS AAQETSEGTE

KM
Length:352
Mass (Da):39,030
Last modified:May 1, 2000 - v1
Checksum:iB8A0D0A43747A236
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07044070 Genomic DNA. No translation available.
AF149717 mRNA. Translation: AAD31721.1.
CH473972 Genomic DNA. Translation: EDL92741.1.
RefSeqiNP_852029.3. NM_181364.4.
XP_017456665.1. XM_017601176.1.
UniGeneiRn.30031.

Genome annotation databases

EnsembliENSRNOT00000017317; ENSRNOP00000017317; ENSRNOG00000012789.
GeneIDi252859.
KEGGirno:252859.
UCSCiRGD:621262. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07044070 Genomic DNA. No translation available.
AF149717 mRNA. Translation: AAD31721.1.
CH473972 Genomic DNA. Translation: EDL92741.1.
RefSeqiNP_852029.3. NM_181364.4.
XP_017456665.1. XM_017601176.1.
UniGeneiRn.30031.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017317.

Chemistry databases

ChEMBLiCHEMBL3875.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000017317; ENSRNOP00000017317; ENSRNOG00000012789.
GeneIDi252859.
KEGGirno:252859.
UCSCiRGD:621262. rat.

Organism-specific databases

CTDi2862.
RGDi621262. Mlnr.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
GeneTreeiENSGT00700000104070.
HOVERGENiHBG007549.
KOiK04282.
OMAiIYGRAGC.
OrthoDBiEOG091G08BE.
TreeFamiTF326170.

Gene expression databases

BgeeiENSRNOG00000012789.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002120. TRH_rcpt_1.
[Graphical view]
PANTHERiPTHR24243:SF51. PTHR24243:SF51. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01654. TRHRECEPTOR2.
PR01846. TRHRFAMILY.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9R297_RAT
AccessioniPrimary (citable) accession number: Q9R297
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 30, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.