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Q9R231

- Q9R231_RAT

UniProt

Q9R231 - Q9R231_RAT

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Protein
Submitted name:

Transforming growth factor beta-1

Gene
Tgfb1
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Source: Ensembl
  2. ATP biosynthetic process Source: Ensembl
  3. branch elongation involved in mammary gland duct branching Source: Ensembl
  4. cell-cell junction organization Source: Ensembl
  5. cell cycle arrest Source: Ensembl
  6. cellular calcium ion homeostasis Source: Ensembl
  7. cellular response to organic cyclic compound Source: Ensembl
  8. chondrocyte differentiation Source: Ensembl
  9. common-partner SMAD protein phosphorylation Source: Ensembl
  10. endoderm development Source: Ensembl
  11. epidermal growth factor receptor signaling pathway Source: Ensembl
  12. evasion or tolerance of host defenses by virus Source: Ensembl
  13. extracellular matrix assembly Source: Ensembl
  14. extrinsic apoptotic signaling pathway Source: Ensembl
  15. face morphogenesis Source: Ensembl
  16. germ cell migration Source: Ensembl
  17. hematopoietic progenitor cell differentiation Source: Ensembl
  18. hyaluronan catabolic process Source: Ensembl
  19. inflammatory response Source: Ensembl
  20. lens fiber cell differentiation Source: Ensembl
  21. lipopolysaccharide-mediated signaling pathway Source: Ensembl
  22. lymph node development Source: Ensembl
  23. mammary gland branching involved in thelarche Source: Ensembl
  24. MAPK cascade Source: Ensembl
  25. mitotic cell cycle checkpoint Source: Ensembl
  26. mononuclear cell proliferation Source: Ensembl
  27. myeloid dendritic cell differentiation Source: Ensembl
  28. negative regulation of blood vessel endothelial cell migration Source: Ensembl
  29. negative regulation of cell-cell adhesion Source: Ensembl
  30. negative regulation of cell growth Source: Ensembl
  31. negative regulation of DNA replication Source: Ensembl
  32. negative regulation of epithelial cell proliferation Source: Ensembl
  33. negative regulation of fat cell differentiation Source: Ensembl
  34. negative regulation of hyaluronan biosynthetic process Source: Ensembl
  35. negative regulation of macrophage cytokine production Source: Ensembl
  36. negative regulation of mitotic cell cycle Source: Ensembl
  37. negative regulation of myoblast differentiation Source: Ensembl
  38. negative regulation of ossification Source: Ensembl
  39. negative regulation of protein phosphorylation Source: Ensembl
  40. negative regulation of skeletal muscle tissue development Source: Ensembl
  41. negative regulation of T cell proliferation Source: Ensembl
  42. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
  43. ossification involved in bone remodeling Source: Ensembl
  44. pathway-restricted SMAD protein phosphorylation Source: Ensembl
  45. positive regulation of blood vessel endothelial cell migration Source: Ensembl
  46. positive regulation of bone mineralization Source: Ensembl
  47. positive regulation of cell cycle arrest Source: Ensembl
  48. positive regulation of cell proliferation Source: Ensembl
  49. positive regulation of chemotaxis Source: Ensembl
  50. positive regulation of collagen biosynthetic process Source: Ensembl
  51. positive regulation of epithelial to mesenchymal transition Source: Ensembl
  52. positive regulation of fibroblast migration Source: Ensembl
  53. positive regulation of histone acetylation Source: Ensembl
  54. positive regulation of histone deacetylation Source: Ensembl
  55. positive regulation of interleukin-17 production Source: Ensembl
  56. positive regulation of isotype switching to IgA isotypes Source: Ensembl
  57. positive regulation of MAP kinase activity Source: Ensembl
  58. positive regulation of NAD+ ADP-ribosyltransferase activity Source: Ensembl
  59. positive regulation of odontogenesis Source: Ensembl
  60. positive regulation of pathway-restricted SMAD protein phosphorylation Source: Ensembl
  61. positive regulation of peptidyl-serine phosphorylation Source: Ensembl
  62. positive regulation of peptidyl-threonine phosphorylation Source: Ensembl
  63. positive regulation of phosphatidylinositol 3-kinase activity Source: Ensembl
  64. positive regulation of protein complex assembly Source: Ensembl
  65. positive regulation of protein dephosphorylation Source: Ensembl
  66. positive regulation of protein kinase B signaling Source: Ensembl
  67. positive regulation of protein secretion Source: Ensembl
  68. positive regulation of SMAD protein import into nucleus Source: Ensembl
  69. positive regulation of superoxide anion generation Source: Ensembl
  70. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  71. positive regulation of transcription regulatory region DNA binding Source: Ensembl
  72. protein export from nucleus Source: Ensembl
  73. protein import into nucleus, translocation Source: Ensembl
  74. protein kinase B signaling Source: Ensembl
  75. receptor catabolic process Source: Ensembl
  76. regulation of branching involved in mammary gland duct morphogenesis Source: Ensembl
  77. regulation of cartilage development Source: Ensembl
  78. regulation of sodium ion transport Source: Ensembl
  79. regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  80. regulatory T cell differentiation Source: Ensembl
  81. response to cholesterol Source: Ensembl
  82. response to estradiol Source: Ensembl
  83. response to progesterone Source: Ensembl
  84. salivary gland morphogenesis Source: Ensembl
  85. SMAD protein complex assembly Source: Ensembl
  86. SMAD protein import into nucleus Source: Ensembl
  87. T cell homeostasis Source: Ensembl
  88. tolerance induction to self antigen Source: Ensembl
  89. transforming growth factor beta receptor signaling pathway Source: Ensembl
  90. ureteric bud development Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor beta-1Imported
Gene namesi
Name:Tgfb1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi69051. Tgfb1.

Subcellular locationi

GO - Cellular componenti

  1. cell surface Source: Ensembl
  2. cytoplasm Source: Ensembl
  3. extracellular space Source: Ensembl
  4. microvillus Source: Ensembl
  5. nucleus Source: Ensembl
  6. proteinaceous extracellular matrix Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ9R231.
GenevestigatoriQ9R231.

Family & Domainsi

Phylogenomic databases

InParanoidiQ9R231.

Sequencei

Sequence statusi: Fragment.

Q9R231-1 [UniParc]FASTAAdd to Basket

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MPPSGLRLLP LLLPLPWLLV LTP                                23
Length:23
Mass (Da):2,550
Last modified:May 1, 2000 - v1
Checksum:i26AA10E5D88E68F4
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei23 – 231Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF105069 Genomic DNA. Translation: AAD20222.1.
UniGeneiRn.40136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF105069 Genomic DNA. Translation: AAD20222.1 .
UniGenei Rn.40136.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 69051. Tgfb1.

Phylogenomic databases

InParanoidi Q9R231.

Gene expression databases

ArrayExpressi Q9R231.
Genevestigatori Q9R231.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Identification of the start sites for the 1.9- and 1.4-kb rat transforming growth factor-beta1 transcripts and their effect on translational efficiency."
    Yang Y., Mumy M., Romeo D., Wakefield L.M.
    Gene 219:81-89(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: FisherImported.

Entry informationi

Entry nameiQ9R231_RAT
AccessioniPrimary (citable) accession number: Q9R231
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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