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Protein

Transgelin-3

Gene

Tagln3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Transgelin-3
Alternative name(s):
Neuronal protein NP25
Gene namesi
Name:Tagln3
Synonyms:Np25
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1926784. Tagln3.

Subcellular locationi

GO - Cellular componenti

  • myelin sheath Source: UniProtKB
  • nucleus Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Transgelin-3PRO_0000204789Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei163 – 1631PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9R1Q8.
MaxQBiQ9R1Q8.
PaxDbiQ9R1Q8.
PeptideAtlasiQ9R1Q8.
PRIDEiQ9R1Q8.

PTM databases

iPTMnetiQ9R1Q8.
PhosphoSiteiQ9R1Q8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000022658.
CleanExiMM_TAGLN3.
GenevisibleiQ9R1Q8. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9R1Q8. 2 interactions.
MINTiMINT-1849802.
STRINGi10090.ENSMUSP00000093762.

Structurei

3D structure databases

ProteinModelPortaliQ9R1Q8.
SMRiQ9R1Q8. Positions 25-153.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 136113CHPROSITE-ProRule annotationAdd
BLAST
Repeati174 – 19926Calponin-likeAdd
BLAST

Sequence similaritiesi

Belongs to the calponin family.Curated
Contains 1 calponin-like repeat.PROSITE-ProRule annotation
Contains 1 CH (calponin-homology) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2046. Eukaryota.
COG5199. LUCA.
GeneTreeiENSGT00550000074447.
HOGENOMiHOG000232113.
HOVERGENiHBG005186.
InParanoidiQ9R1Q8.
OMAiGMPRQII.
OrthoDBiEOG091G0LY2.
PhylomeDBiQ9R1Q8.
TreeFamiTF313921.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
InterProiIPR000557. Calponin_repeat.
IPR001715. CH-domain.
IPR003096. SM22_calponin.
[Graphical view]
PfamiPF00402. Calponin. 1 hit.
PF00307. CH. 1 hit.
[Graphical view]
PRINTSiPR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS01052. CALPONIN_1. 1 hit.
PS51122. CALPONIN_2. 1 hit.
PS50021. CH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9R1Q8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANRGPSYGL SREVQEKIEQ KYDADLENKL VDWIILQCAE DIEHPPPGRA
60 70 80 90 100
HFQKWLMDGT VLCKLINSLY PPGQEPIPKI SESKMAFKQM EQISQFLKAA
110 120 130 140 150
EVYGVRTTDI FQTVDLWEGK DMAAVQRTLM ALGSVAVTKD DGCYRGEPSW
160 170 180 190
FHRKAQQNRR GFSEEQLRQG QNVIGLQMGS NKGASQAGMT GYGMPRQIM
Length:199
Mass (Da):22,471
Last modified:May 1, 2000 - v1
Checksum:i53802F6F94958202
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB031291 mRNA. Translation: BAA83499.1.
BC043027 mRNA. Translation: AAH43027.1.
BC055338 mRNA. Translation: AAH55338.1.
CCDSiCCDS28200.1.
RefSeqiNP_062728.1. NM_019754.3.
UniGeneiMm.24183.

Genome annotation databases

EnsembliENSMUST00000096057; ENSMUSP00000093762; ENSMUSG00000022658.
GeneIDi56370.
KEGGimmu:56370.
UCSCiuc007ziw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB031291 mRNA. Translation: BAA83499.1.
BC043027 mRNA. Translation: AAH43027.1.
BC055338 mRNA. Translation: AAH55338.1.
CCDSiCCDS28200.1.
RefSeqiNP_062728.1. NM_019754.3.
UniGeneiMm.24183.

3D structure databases

ProteinModelPortaliQ9R1Q8.
SMRiQ9R1Q8. Positions 25-153.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9R1Q8. 2 interactions.
MINTiMINT-1849802.
STRINGi10090.ENSMUSP00000093762.

PTM databases

iPTMnetiQ9R1Q8.
PhosphoSiteiQ9R1Q8.

Proteomic databases

EPDiQ9R1Q8.
MaxQBiQ9R1Q8.
PaxDbiQ9R1Q8.
PeptideAtlasiQ9R1Q8.
PRIDEiQ9R1Q8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000096057; ENSMUSP00000093762; ENSMUSG00000022658.
GeneIDi56370.
KEGGimmu:56370.
UCSCiuc007ziw.1. mouse.

Organism-specific databases

CTDi29114.
MGIiMGI:1926784. Tagln3.

Phylogenomic databases

eggNOGiKOG2046. Eukaryota.
COG5199. LUCA.
GeneTreeiENSGT00550000074447.
HOGENOMiHOG000232113.
HOVERGENiHBG005186.
InParanoidiQ9R1Q8.
OMAiGMPRQII.
OrthoDBiEOG091G0LY2.
PhylomeDBiQ9R1Q8.
TreeFamiTF313921.

Miscellaneous databases

PROiQ9R1Q8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022658.
CleanExiMM_TAGLN3.
GenevisibleiQ9R1Q8. MM.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
InterProiIPR000557. Calponin_repeat.
IPR001715. CH-domain.
IPR003096. SM22_calponin.
[Graphical view]
PfamiPF00402. Calponin. 1 hit.
PF00307. CH. 1 hit.
[Graphical view]
PRINTSiPR00888. SM22CALPONIN.
SMARTiSM00033. CH. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
PROSITEiPS01052. CALPONIN_1. 1 hit.
PS51122. CALPONIN_2. 1 hit.
PS50021. CH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTAGL3_MOUSE
AccessioniPrimary (citable) accession number: Q9R1Q8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.