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Protein

Proteolipid protein 2

Gene

Plp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in cell differentiation in the intestinal epithelium.By similarity

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Proteolipid protein 2
Gene namesi
Name:Plp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 13, Chromosome X

Organism-specific databases

MGIiMGI:1298382 Plp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001568201 – 152Proteolipid protein 2Add BLAST152

Proteomic databases

EPDiQ9R1Q7
MaxQBiQ9R1Q7
PaxDbiQ9R1Q7
PRIDEiQ9R1Q7

PTM databases

iPTMnetiQ9R1Q7
PhosphoSitePlusiQ9R1Q7
SwissPalmiQ9R1Q7

Expressioni

Gene expression databases

BgeeiENSMUSG00000031146
CleanExiMM_PLP2
ExpressionAtlasiQ9R1Q7 baseline and differential
GenevisibleiQ9R1Q7 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ9R1Q7, 3 interactors
STRINGi10090.ENSMUSP00000132645

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 138MARVELPROSITE-ProRule annotationAdd BLAST120

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4788 Eukaryota
ENOG4111IAF LUCA
GeneTreeiENSGT00530000063326
HOGENOMiHOG000293179
HOVERGENiHBG099247
InParanoidiQ9R1Q7
OMAiIYMCDLH
OrthoDBiEOG091G0SSY
PhylomeDBiQ9R1Q7
TreeFamiTF317387

Family and domain databases

InterProiView protein in InterPro
IPR008253 Marvel
PfamiView protein in Pfam
PF01284 MARVEL, 1 hit
PROSITEiView protein in PROSITE
PS51225 MARVEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q9R1Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSERLSAP GCWLACTSFS RTKKGILLFA EIILCLVILI CFSASTTSAY
60 70 80 90 100
SSLSVIEMIC AAVLLVFYTC DLHSKISFIN WPWTDFFRSL IATILYLITS
110 120 130 140 150
IVVLVEGRGS SRVVAGILGL LATLLFGYDA YITFPLKQQR HTAAPTDPTD

GP
Length:152
Mass (Da):16,608
Last modified:May 1, 2000 - v1
Checksum:iC651A5E43B2909D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB031292 mRNA Translation: BAA83500.1
AK003522 mRNA Translation: BAB22835.1
AK011282 mRNA Translation: BAB27515.1
AK154228 mRNA Translation: BAE32448.1
BC083078 mRNA Translation: AAH83078.1
CCDSiCCDS40842.1
RefSeqiNP_062729.1, NM_019755.5
UniGeneiMm.18565
Mm.432064
Mm.463231

Genome annotation databases

EnsembliENSMUST00000033486; ENSMUSP00000033486; ENSMUSG00000031146
ENSMUST00000071118; ENSMUSP00000132645; ENSMUSG00000057762
GeneIDi18824
KEGGimmu:18824
UCSCiuc009slx.1 mouse

Similar proteinsi

Entry informationi

Entry nameiPLP2_MOUSE
AccessioniPrimary (citable) accession number: Q9R1Q7
Secondary accession number(s): Q3U4I3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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