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Q9R1Q7 (PLP2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteolipid protein 2
Gene names
Name:Plp2
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length152 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May play a role in cell differentiation in the intestinal epithelium By similarity.

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Contains 1 MARVEL domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 152152Proteolipid protein 2
PRO_0000156820

Regions

Transmembrane25 – 4521Helical; Potential
Transmembrane48 – 6821Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane112 – 13221Helical; Potential
Domain19 – 138120MARVEL

Sequences

Sequence LengthMass (Da)Tools
Q9R1Q7 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: C651A5E43B2909D6

FASTA15216,608
        10         20         30         40         50         60 
MADSERLSAP GCWLACTSFS RTKKGILLFA EIILCLVILI CFSASTTSAY SSLSVIEMIC 

        70         80         90        100        110        120 
AAVLLVFYTC DLHSKISFIN WPWTDFFRSL IATILYLITS IVVLVEGRGS SRVVAGILGL 

       130        140        150 
LATLLFGYDA YITFPLKQQR HTAAPTDPTD GP 

« Hide

References

« Hide 'large scale' references
[1]"Mouse proteolipid protein 2 (PLP2)."
Hayashi A., Hattori A., Okaze H., Kozuma S., Seki N., Saito T.
Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and NOD.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Colon.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB031292 mRNA. Translation: BAA83500.1.
AK003522 mRNA. Translation: BAB22835.1.
AK011282 mRNA. Translation: BAB27515.1.
AK154228 mRNA. Translation: BAE32448.1.
BC083078 mRNA. Translation: AAH83078.1.
CCDSCCDS40842.1.
RefSeqNP_062729.1. NM_019755.4.
UniGeneMm.18565.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9R1Q7. 1 interaction.
MINTMINT-1544053.

PTM databases

PhosphoSiteQ9R1Q7.

Proteomic databases

PaxDbQ9R1Q7.
PRIDEQ9R1Q7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000033486; ENSMUSP00000033486; ENSMUSG00000031146.
ENSMUST00000071118; ENSMUSP00000132645; ENSMUSG00000057762.
GeneID18824.
KEGGmmu:18824.
UCSCuc009slx.1. mouse.

Organism-specific databases

CTD5355.
MGIMGI:1298382. Plp2.

Phylogenomic databases

eggNOGNOG296424.
GeneTreeENSGT00530000063326.
HOGENOMHOG000293179.
HOVERGENHBG099247.
InParanoidQ9R1Q7.
OMAIYMCDLH.
OrthoDBEOG7DNNXK.
PhylomeDBQ9R1Q7.
TreeFamTF317387.

Gene expression databases

BgeeQ9R1Q7.
CleanExMM_PLP2.
GenevestigatorQ9R1Q7.

Family and domain databases

InterProIPR008253. Marvel.
[Graphical view]
PfamPF01284. MARVEL. 1 hit.
[Graphical view]
PROSITEPS51225. MARVEL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio295192.
PROQ9R1Q7.
SOURCESearch...

Entry information

Entry namePLP2_MOUSE
AccessionPrimary (citable) accession number: Q9R1Q7
Secondary accession number(s): Q3U4I3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot