Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9R1K7

- TBD_MOUSE

UniProt

Q9R1K7 - TBD_MOUSE

Protein

Tubulin delta chain

Gene

Tubd1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 May 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi143 – 1497GTPSequence Analysis

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-KW
    3. structural constituent of cytoskeleton Source: InterPro

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. microtubule-based process Source: InterPro
    3. multicellular organismal development Source: UniProtKB-KW
    4. protein polymerization Source: InterPro
    5. spermatogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Spermatogenesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tubulin delta chain
    Alternative name(s):
    Delta-tubulin
    Gene namesi
    Name:Tubd1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1891826. Tubd1.

    Subcellular locationi

    Cytoplasmcytoskeletonmicrotubule organizing centercentrosomecentriole. Cytoplasm. Nucleus
    Note: Associated with centrioles. Both cytoplasmic and nuclear.

    GO - Cellular componenti

    1. centriole Source: UniProtKB-SubCell
    2. cytoplasm Source: MGI
    3. microtubule Source: UniProtKB-KW
    4. nucleus Source: MGI

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton, Microtubule, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 455455Tubulin delta chainPRO_0000048485Add
    BLAST

    Proteomic databases

    PRIDEiQ9R1K7.

    PTM databases

    PhosphoSiteiQ9R1K7.

    Expressioni

    Tissue specificityi

    Highly expressed in testis.

    Gene expression databases

    ArrayExpressiQ9R1K7.
    BgeeiQ9R1K7.
    CleanExiMM_TUBD1.
    GenevestigatoriQ9R1K7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9R1K7.
    SMRiQ9R1K7. Positions 3-450.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tubulin family.Curated

    Phylogenomic databases

    eggNOGiCOG5023.
    GeneTreeiENSGT00530000063251.
    HOGENOMiHOG000006615.
    HOVERGENiHBG000807.
    KOiK10390.
    OrthoDBiEOG7KH9JK.
    TreeFamiTF329833.

    Family and domain databases

    Gene3Di1.10.287.600. 1 hit.
    3.40.50.1440. 1 hit.
    InterProiIPR002967. Delta_tubulin.
    IPR008280. Tub_FtsZ_C.
    IPR000217. Tubulin.
    IPR023123. Tubulin_C.
    IPR017975. Tubulin_CS.
    IPR003008. Tubulin_FtsZ_GTPase.
    [Graphical view]
    PANTHERiPTHR11588. PTHR11588. 1 hit.
    PTHR11588:SF4. PTHR11588:SF4. 1 hit.
    PfamiPF00091. Tubulin. 1 hit.
    [Graphical view]
    PRINTSiPR01224. DELTATUBULIN.
    PR01161. TUBULIN.
    SMARTiSM00864. Tubulin. 1 hit.
    [Graphical view]
    SUPFAMiSSF52490. SSF52490. 1 hit.
    SSF55307. SSF55307. 1 hit.
    PROSITEiPS00227. TUBULIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9R1K7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIVTVQLGQ CGNQIGFEVF DALFRDSHCS QGLCSKRDNE AYQASCRERF    50
    FREEENGVPV ARAVLVDMEP KVINQTLSKA AQSGRWNYGQ HTSFCQKQGS 100
    GNNWAYGYSV HGPKHEESIM NLIQTEVEKC DSLSGFFIIM SMAGGTGSGL 150
    GAFVTQKLQD QYSSSLKMNQ IIWPYGTGEV IVQNYNSILT LSHLYRSSDA 200
    LLIHENDAVH KICAKRMNIK QISFRDLNQV LAHQLGSVFQ PTYSEDSSFH 250
    YRRNPLGDLM EHLVPHPEFK MLGVRNIPQM SAASLAYSAF TWAGLLKHLR 300
    QMLISSAKME EGINWQVRPP LTGLPPIGKA SAHKEHHFNT SLANLVVLRG 350
    REVHSADVEG FKDPALYTSW LEPVDAFSVW KTQRAFDKYE KSAALVSNSQ 400
    LLVKPLDMIV GKAWNMFSSK AFIHQYTKFG MEEEDFLDSF ALLEQVVASY 450
    GSLGP 455
    Length:455
    Mass (Da):51,023
    Last modified:May 1, 2000 - v1
    Checksum:i97755668BC193092
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF081568 mRNA. Translation: AAD52009.1.
    BC026465 mRNA. Translation: AAH26465.1.
    CCDSiCCDS25202.1.
    RefSeqiNP_001185976.1. NM_001199047.1.
    NP_062730.1. NM_019756.3.
    UniGeneiMm.383207.

    Genome annotation databases

    EnsembliENSMUST00000069503; ENSMUSP00000064383; ENSMUSG00000020513.
    ENSMUST00000167178; ENSMUSP00000130909; ENSMUSG00000020513.
    GeneIDi56427.
    KEGGimmu:56427.
    UCSCiuc007kss.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF081568 mRNA. Translation: AAD52009.1 .
    BC026465 mRNA. Translation: AAH26465.1 .
    CCDSi CCDS25202.1.
    RefSeqi NP_001185976.1. NM_001199047.1.
    NP_062730.1. NM_019756.3.
    UniGenei Mm.383207.

    3D structure databases

    ProteinModelPortali Q9R1K7.
    SMRi Q9R1K7. Positions 3-450.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9R1K7.

    Proteomic databases

    PRIDEi Q9R1K7.

    Protocols and materials databases

    DNASUi 56427.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000069503 ; ENSMUSP00000064383 ; ENSMUSG00000020513 .
    ENSMUST00000167178 ; ENSMUSP00000130909 ; ENSMUSG00000020513 .
    GeneIDi 56427.
    KEGGi mmu:56427.
    UCSCi uc007kss.1. mouse.

    Organism-specific databases

    CTDi 51174.
    MGIi MGI:1891826. Tubd1.

    Phylogenomic databases

    eggNOGi COG5023.
    GeneTreei ENSGT00530000063251.
    HOGENOMi HOG000006615.
    HOVERGENi HBG000807.
    KOi K10390.
    OrthoDBi EOG7KH9JK.
    TreeFami TF329833.

    Miscellaneous databases

    NextBioi 312590.
    PROi Q9R1K7.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9R1K7.
    Bgeei Q9R1K7.
    CleanExi MM_TUBD1.
    Genevestigatori Q9R1K7.

    Family and domain databases

    Gene3Di 1.10.287.600. 1 hit.
    3.40.50.1440. 1 hit.
    InterProi IPR002967. Delta_tubulin.
    IPR008280. Tub_FtsZ_C.
    IPR000217. Tubulin.
    IPR023123. Tubulin_C.
    IPR017975. Tubulin_CS.
    IPR003008. Tubulin_FtsZ_GTPase.
    [Graphical view ]
    PANTHERi PTHR11588. PTHR11588. 1 hit.
    PTHR11588:SF4. PTHR11588:SF4. 1 hit.
    Pfami PF00091. Tubulin. 1 hit.
    [Graphical view ]
    PRINTSi PR01224. DELTATUBULIN.
    PR01161. TUBULIN.
    SMARTi SM00864. Tubulin. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52490. SSF52490. 1 hit.
    SSF55307. SSF55307. 1 hit.
    PROSITEi PS00227. TUBULIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Tissue-specific expression and subcellular localisation of mammalian delta-tubulin."
      Smrzka O.W., Delgehyr N., Bornens M.
      Curr. Biol. 10:413-416(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: BALB/c.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary gland.

    Entry informationi

    Entry nameiTBD_MOUSE
    AccessioniPrimary (citable) accession number: Q9R1K7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 11, 2002
    Last sequence update: May 1, 2000
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3