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Q9R1K7 (TBD_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tubulin delta chain
Alternative name(s):
Delta-tubulin
Gene names
Name:Tubd1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

In the elongating spermatid it is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head.

Subcellular location

Cytoplasmcytoskeletonmicrotubule organizing centercentrosomecentriole. Cytoplasm. Nucleus. Note: Associated with centrioles. Both cytoplasmic and nuclear.

Tissue specificity

Highly expressed in testis.

Sequence similarities

Belongs to the tubulin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 455455Tubulin delta chain
PRO_0000048485

Regions

Nucleotide binding143 – 1497GTP Potential

Sequences

Sequence LengthMass (Da)Tools
Q9R1K7 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 97755668BC193092

FASTA45551,023
        10         20         30         40         50         60 
MSIVTVQLGQ CGNQIGFEVF DALFRDSHCS QGLCSKRDNE AYQASCRERF FREEENGVPV 

        70         80         90        100        110        120 
ARAVLVDMEP KVINQTLSKA AQSGRWNYGQ HTSFCQKQGS GNNWAYGYSV HGPKHEESIM 

       130        140        150        160        170        180 
NLIQTEVEKC DSLSGFFIIM SMAGGTGSGL GAFVTQKLQD QYSSSLKMNQ IIWPYGTGEV 

       190        200        210        220        230        240 
IVQNYNSILT LSHLYRSSDA LLIHENDAVH KICAKRMNIK QISFRDLNQV LAHQLGSVFQ 

       250        260        270        280        290        300 
PTYSEDSSFH YRRNPLGDLM EHLVPHPEFK MLGVRNIPQM SAASLAYSAF TWAGLLKHLR 

       310        320        330        340        350        360 
QMLISSAKME EGINWQVRPP LTGLPPIGKA SAHKEHHFNT SLANLVVLRG REVHSADVEG 

       370        380        390        400        410        420 
FKDPALYTSW LEPVDAFSVW KTQRAFDKYE KSAALVSNSQ LLVKPLDMIV GKAWNMFSSK 

       430        440        450 
AFIHQYTKFG MEEEDFLDSF ALLEQVVASY GSLGP 

« Hide

References

« Hide 'large scale' references
[1]"Tissue-specific expression and subcellular localisation of mammalian delta-tubulin."
Smrzka O.W., Delgehyr N., Bornens M.
Curr. Biol. 10:413-416(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: BALB/c.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF081568 mRNA. Translation: AAD52009.1.
BC026465 mRNA. Translation: AAH26465.1.
RefSeqNP_001185976.1. NM_001199047.1.
NP_062730.1. NM_019756.3.
UniGeneMm.383207.

3D structure databases

ProteinModelPortalQ9R1K7.
SMRQ9R1K7. Positions 3-450.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9R1K7.

Proteomic databases

PRIDEQ9R1K7.

Protocols and materials databases

DNASU56427.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000069503; ENSMUSP00000064383; ENSMUSG00000020513.
ENSMUST00000167178; ENSMUSP00000130909; ENSMUSG00000020513.
GeneID56427.
KEGGmmu:56427.
UCSCuc007kss.1. mouse.

Organism-specific databases

CTD51174.
MGIMGI:1891826. Tubd1.

Phylogenomic databases

eggNOGCOG5023.
GeneTreeENSGT00530000063251.
HOGENOMHOG000006615.
HOVERGENHBG000807.
KOK10390.
OrthoDBEOG7KH9JK.
TreeFamTF329833.

Gene expression databases

ArrayExpressQ9R1K7.
BgeeQ9R1K7.
CleanExMM_TUBD1.
GenevestigatorQ9R1K7.

Family and domain databases

Gene3D1.10.287.600. 1 hit.
3.40.50.1440. 1 hit.
InterProIPR002967. Delta_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR023123. Tubulin_C.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PANTHERPTHR11588. PTHR11588. 1 hit.
PTHR11588:SF4. PTHR11588:SF4. 1 hit.
PfamPF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSPR01224. DELTATUBULIN.
PR01161. TUBULIN.
SMARTSM00864. Tubulin. 1 hit.
[Graphical view]
SUPFAMSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEPS00227. TUBULIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio312590.
PROQ9R1K7.
SOURCESearch...

Entry information

Entry nameTBD_MOUSE
AccessionPrimary (citable) accession number: Q9R1K7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 11, 2002
Last sequence update: May 1, 2000
Last modified: February 19, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot