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Q9R182 (ANGL3_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Angiopoietin-related protein 3
Alternative name(s):
Angiopoietin-like protein 3
Gene names
Name:Angptl3
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted By similarity.

Sequence similarities

Contains 1 fibrinogen C-terminal domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Chain17 – 455439Angiopoietin-related protein 3
PRO_0000009123

Regions

Domain237 – 455219Fibrinogen C-terminal
Coiled coil85 – 206122 Potential

Amino acid modifications

Glycosylation1151N-linked (GlcNAc...) Potential
Glycosylation2321N-linked (GlcNAc...) Potential
Glycosylation2961N-linked (GlcNAc...) Potential
Glycosylation3571N-linked (GlcNAc...) Potential
Disulfide bond246 ↔ 274 By similarity
Disulfide bond394 ↔ 408 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9R182 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 31609D3700D3F33D

FASTA45552,543
        10         20         30         40         50         60 
MHTIKLFLFV VPLVIASRVD PDLSSFDSAP SEPKSRFAML DDVKILANGL LQLGHGLKDF 

        70         80         90        100        110        120 
VHKTKGQIND IFQKLNIFDQ SFYDLSLRTN EIKEEEKELR RTTSTLQVKN EEVKNMSVEL 

       130        140        150        160        170        180 
NSKLESLLEE KTALQHKVRA LEEQLTNLIL SPAGAQEHPE VTSLKSFVEQ QDNSIRELLQ 

       190        200        210        220        230        240 
SVEEQYKQLS QQHMQIKEIE KQLRKTGIQE PSENSLSSKS RAPRTTPPLQ LNETENTEQD 

       250        260        270        280        290        300 
DLPADCSAVY NRGEHTSGVY TIKPRNSQGF NVYCDTQSGS PWTLIQHRKD GSQDFNETWE 

       310        320        330        340        350        360 
NYEKGFGRLD GEFWLGLEKI YAIVQQSNYI LRLELQDWKD SKHYVEYSFH LGSHETNYTL 

       370        380        390        400        410        420 
HVAEIAGNIP GALPEHTDLM FSTWNHRAKG QLYCPESYSG GWWWNDICGE NNLNGKYNKP 

       430        440        450 
RTKSRPERRR GIYWRPQSRK LYAIKSSKMM LQPTT

« Hide

References

« Hide 'large scale' references
[1]"Identification of a mammalian angiopoietin-related protein expressed specifically in liver."
Conklin D., Gilbertson D., Taft D.W., Maurer M.F., Whitmore T.E., Smith D.L., Walker K.M., Chen L.H., Wattler S., Nehls M., Lewis K.B.
Genomics 62:477-482(1999) [PubMed: 10644446] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Liver.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF162224 mRNA. Translation: AAD45920.1.
BC019491 mRNA. Translation: AAH19491.1.
IPIIPI00128206.
RefSeqNP_038941.1. NM_013913.3.
UniGeneMm.28341.

3D structure databases

ProteinModelPortalQ9R182.
SMRQ9R182. Positions 243-454.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9R182.

PTM databases

PhosphoSiteQ9R182.

Proteomic databases

PRIDEQ9R182.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000030280; ENSMUSP00000030280; ENSMUSG00000028553.
GeneID30924.
KEGGmmu:30924.

Organism-specific databases

CTD27329.
MGIMGI:1353627. Angptl3.

Phylogenomic databases

GeneTreeENSGT00560000076679.
HOGENOMHBG713975.
HOVERGENHBG001644.
InParanoidQ9R182.
OMARGEHTSG.
OrthoDBEOG4G1MGS.
PhylomeDBQ9R182.

Gene expression databases

ArrayExpressQ9R182.
BgeeQ9R182.
CleanExMM_ANGPTL3.
GenevestigatorQ9R182.
GermOnlineENSMUSG00000028553. Mus musculus.

Family and domain databases

InterProIPR002181. Fibrinogen_a/b/g_C.
IPR014716. Fibrinogen_a/b/g_C_1.
IPR014715. Fibrinogen_a/b/g_C_2.
[Graphical view]
Gene3DG3DSA:3.90.215.10. Fibrinogen_a/b/g_C_1. 1 hit.
G3DSA:4.10.530.10. Fibrinogen_a/b/g_C_2. 1 hit.
PfamPF00147. Fibrinogen_C. 1 hit.
[Graphical view]
SMARTSM00186. FBG. 1 hit.
[Graphical view]
SUPFAMSSF56496. Fibrinogen_a/b/g_C. 1 hit.
PROSITEPS00514. FIBRINOGEN_C_1. False negative.
PS51406. FIBRINOGEN_C_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio307316.
SOURCESearch...

Entry information

Entry nameANGL3_MOUSE
AccessionPrimary (citable) accession number: Q9R182
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: May 1, 2000
Last modified: September 21, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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