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Reviewed, UniProtKB/Swiss-Prot Q9R182 (ANGL3_MOUSE)

Last modified January 19, 2010. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Angiopoietin-related protein 3
Alternative name(s):
    Angiopoietin-like protein 3
Gene names
Name: Angptl3
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Subcellular location

Secreted By similarity.

Sequence similarities

Contains 1 fibrinogen C-terminal domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Chain17 – 455439Angiopoietin-related protein 3
PRO_0000009123

Regions

Domain237 – 455219Fibrinogen C-terminal
Coiled coil85 – 206122 Potential

Amino acid modifications

Glycosylation1151N-linked (GlcNAc...) Potential
Glycosylation2321N-linked (GlcNAc...) Potential
Glycosylation2961N-linked (GlcNAc...) Potential
Glycosylation3571N-linked (GlcNAc...) Potential
Disulfide bond246 ↔ 274 By similarity
Disulfide bond394 ↔ 408 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q9R182-1 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 31609D3700D3F33D

FASTA45552,543
        10         20         30         40         50         60 
MHTIKLFLFV VPLVIASRVD PDLSSFDSAP SEPKSRFAML DDVKILANGL LQLGHGLKDF 

        70         80         90        100        110        120 
VHKTKGQIND IFQKLNIFDQ SFYDLSLRTN EIKEEEKELR RTTSTLQVKN EEVKNMSVEL 

       130        140        150        160        170        180 
NSKLESLLEE KTALQHKVRA LEEQLTNLIL SPAGAQEHPE VTSLKSFVEQ QDNSIRELLQ 

       190        200        210        220        230        240 
SVEEQYKQLS QQHMQIKEIE KQLRKTGIQE PSENSLSSKS RAPRTTPPLQ LNETENTEQD 

       250        260        270        280        290        300 
DLPADCSAVY NRGEHTSGVY TIKPRNSQGF NVYCDTQSGS PWTLIQHRKD GSQDFNETWE 

       310        320        330        340        350        360 
NYEKGFGRLD GEFWLGLEKI YAIVQQSNYI LRLELQDWKD SKHYVEYSFH LGSHETNYTL 

       370        380        390        400        410        420 
HVAEIAGNIP GALPEHTDLM FSTWNHRAKG QLYCPESYSG GWWWNDICGE NNLNGKYNKP 

       430        440        450 
RTKSRPERRR GIYWRPQSRK LYAIKSSKMM LQPTT

« Hide

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References

« Hide 'large scale' references
[1]"Identification of a mammalian angiopoietin-related protein expressed specifically in liver."
Conklin D., Gilbertson D., Taft D.W., Maurer M.F., Whitmore T.E., Smith D.L., Walker K.M., Chen L.H., Wattler S., Nehls M., Lewis K.B.
Genomics 62:477-482(1999) [PubMed: 10644446] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Liver.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF162224 mRNA. Translation: AAD45920.1.
BC019491 mRNA. Translation: AAH19491.1.
IPIIPI00128206.
RefSeqNP_038941.1.
UniGeneMm.28341

3D structure databases

SMRQ9R182. Positions 281-454.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9R182.

Proteomic databases

PRIDEQ9R182.

Genome annotation databases

EnsemblENSMUST00000030280; ENSMUSP00000030280; ENSMUSG00000028553; Mus musculus. [Genome view]
GeneID30924.
KEGGmmu:30924.
UCSCuc008tur.1. mouse.

Organism-specific databases

CTD30924.
MGIMGI:1353627. Angptl3.

Phylogenomic databases

HOGENOMHBG713975.
HOVERGENQ9R182.
InParanoidQ9R182.
OMARGEHTSG.
OrthoDBEOG9QJV6X.
PhylomeDBQ9R182.

Gene expression databases

ArrayExpressQ9R182.
BgeeQ9R182.
CleanExMM_ANGPTL3.
GenevestigatorQ9R182.
GermOnlineENSMUSG00000028553. Mus musculus.

Family and domain databases

InterProIPR002181. Fibrinogen_a/b/g_C.
IPR014716. Fibrinogen_a/b/g_C_1.
[Graphical view]
Gene3DG3DSA:3.90.215.10. Fibrinogen_a/b/g_C_1. 1 hit.
PfamPF00147. Fibrinogen_C. 1 hit.
[Graphical view]
SMARTSM00186. FBG. 1 hit.
[Graphical view]
PROSITEPS00514. FIBRINOGEN_C_1. False negative.
PS51406. FIBRINOGEN_C_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio307316.
SOURCESearch...

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Entry information

Entry nameANGL3_MOUSE
AccessionPrimary (citable) accession number: Q9R182
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: May 1, 2000
Last modified: January 19, 2010
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents