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Protein
Submitted name:

Sonic hedgehog protein

Gene

Shh

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_308621. Ligand-receptor interactions.
REACT_323768. Class B/2 (Secretin family receptors).
REACT_328270. Release of Hh-Np from the secreting cell.
REACT_336611. Hedgehog ligand biogenesis.

Names & Taxonomyi

Protein namesi
Submitted name:
Sonic hedgehog proteinImported
Gene namesi
Name:ShhImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi3673. Shh.

Expressioni

Gene expression databases

ExpressionAtlasiQ9R179. baseline.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008497.

Structurei

3D structure databases

ProteinModelPortaliQ9R179.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG005480.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.30.1380.10. 1 hit.
InterProiIPR001657. Hedgehog.
IPR028992. Hedgehog/Intein_dom.
IPR009045. Hedgehog_sig/DD-Pept_Zn-bd_dom.
IPR000320. Hedgehog_signalling_dom.
IPR001767. Hint_dom.
[Graphical view]
PfamiPF01085. HH_signal. 1 hit.
PF01079. Hint. 1 hit.
[Graphical view]
PRINTSiPR00632. SONICHHOG.
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF55166. SSF55166. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9R179-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IIFKDEENTG ADRLMTQRCK DKLNALAISV MNQWPGVKLR VTEGWDEDGH
60 70 80 90 100
HSEESLHYEG RAVDITTSDR DRSKYGMLAR LAVEAGFDWV YYESKAHIHC
110 120 130 140 150
SVKAENSVAA KSGGCFPGSA TVHLEQGGTK LVKDLSPGDR VLAADDQGRL
160
LYSDFLTFLD R
Length:161
Mass (Da):17,906
Last modified:May 1, 2000 - v1
Checksum:iDF06D85FD45AE4DB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei161 – 1611Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF162915 mRNA. Translation: AAD45373.1.
UniGeneiRn.10432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF162915 mRNA. Translation: AAD45373.1.
UniGeneiRn.10432.

3D structure databases

ProteinModelPortaliQ9R179.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008497.

Chemistry

BindingDBiQ9R179.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi3673. Shh.

Phylogenomic databases

HOVERGENiHBG005480.

Enzyme and pathway databases

ReactomeiREACT_308621. Ligand-receptor interactions.
REACT_323768. Class B/2 (Secretin family receptors).
REACT_328270. Release of Hh-Np from the secreting cell.
REACT_336611. Hedgehog ligand biogenesis.

Gene expression databases

ExpressionAtlasiQ9R179. baseline.

Family and domain databases

Gene3Di2.170.16.10. 1 hit.
3.30.1380.10. 1 hit.
InterProiIPR001657. Hedgehog.
IPR028992. Hedgehog/Intein_dom.
IPR009045. Hedgehog_sig/DD-Pept_Zn-bd_dom.
IPR000320. Hedgehog_signalling_dom.
IPR001767. Hint_dom.
[Graphical view]
PfamiPF01085. HH_signal. 1 hit.
PF01079. Hint. 1 hit.
[Graphical view]
PRINTSiPR00632. SONICHHOG.
SUPFAMiSSF51294. SSF51294. 1 hit.
SSF55166. SSF55166. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Sonic hedgehog in the rat."
    Garges P.L., Meyer R.A.Jr., Brown C.A., Price D.K.
    Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ9R179_RAT
AccessioniPrimary (citable) accession number: Q9R179
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 22, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.