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Protein
Submitted name:

ATPase 7B

Gene

Atp7b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cation-transporting ATPase activity Source: InterPro
  3. copper ion binding Source: InterPro

GO - Biological processi

  1. metal ion transport Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_345620. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Submitted name:
ATPase 7BImported
Gene namesi
Name:Atp7bImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2180. Atp7b.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

ExpressionAtlasiQ9R0T2. baseline.
GenevestigatoriQ9R0T2.

Structurei

3D structure databases

ProteinModelPortaliQ9R0T2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG050616.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
IPR006122. HMA_Cu_ion-bd.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 5 hits.
PF00702. Hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF55008. SSF55008. 6 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
TIGR00003. TIGR00003. 5 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 5 hits.
PS50846. HMA_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9R0T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEQERKVTA KEASRKILSK LALPTRPWGQ SMKQSFAFDN VGYEGGLDST
60 70 80 90 100
CSSSTTTGVV SILGMTCHSC VKSIEDRISS LKGIVSIKVS LEQGSATVKY
110 120 130 140 150
VPSVLNLQQI CLQIEDMGFE ASAAEGKAAS WPSRSSPAQE AVVKLRVEGM
160 170 180 190 200
TCQSCVSSIE GKIRKLQGVV RVKVSLSNQE AVITYQPYLI QPEDLRDHIC
210 220 230 240 250
DMGFEAAIKN RTAPLRLGPI DINKLESTNL KRAAVPPIQN SNHLETPGHQ
260 270 280 290 300
QNHLATLPLR IDGMHCKSCV LNIEGNIGQL PGVQNIHVSL ENKTAQVQYD
310 320 330 340 350
SSCITPLFLQ TAIEALPPGY FKVSLPDGLE KESGSSSVPS LGSSQRQQEP
360 370 380 390 400
GPCRTAVLTI TGIPRDSSVQ PMEDMLSQMK GVQQIDISLA EGTGAVLYDP
410 420 430 440 450
SVVSSDELRT AVEDMGFEVS VNPENITTNR VSSGNSVPQA VGDSPGSVQN
460 470 480 490 500
MASDTRGLLT HQGPGYLSDS PPSPGGTASQ KCFVQIKGMT CASCVSNIER
510 520 530 540 550
SLQRHAGILS VLVALMSGKA EVKYDPEVIQ SPRIAQLIED LGFEAAIMED
560 570 580 590 600
NTVSEGDIEL IITGMTCASC VHNIESKLTR TNGITYASVA LATSKAHVKF
610 620 630 640 650
DPEIIGPRDI IKVIEEIGFH ASLAHRNPNA HHLDHKTEIK QWKKSFLCSL
660 670 680 690 700
VFGIPVMGLM IYMLIPSSKP HETMVLDHNI IPGLSVLNLI FFILCTFVQF
710 720 730 740 750
LGGWYFYVQA YKSLRHKSAN MDVLIVLATT IAYAYSLVIL VVAIAEKAEK
760 770 780 790 800
SPVTFFDTPP MLFVFIALGR WLEHVAKSKT SEALAKLMSL QATEATVVTL
810 820 830 840 850
GEDNLILREE QVPMELVQRG DIIKVVPGGK FPVDGKVLEG NTMADESLIT
860 870 880 890 900
GEAMPVTKKP GSIVIAGSIN AHGSVLIKAT HVGNDTTLAQ IVKLVEEAQM
910 920 930 940 950
SKAPIQQLAD RFSGYFVPFI IIISTLTLVV WIIIGFVDFG IVQKYFPSPS
960 970 980 990 1000
KHISQTEVII RFAFQTSITV LCIACPCSLG LATPTAVMVG TGVAAQNGVL
1010 1020 1030 1040 1050
IKGGKPLEMA HKIKTVMFDK TGTITHGVPR VMRFLLLVDV ATLSLRKVLA
1060 1070 1080 1090 1100
VVGTAEASSE HPLGVAVTKY CKEELGTETL GYSTDFQAVP GCGISCKVSN
1110 1120
VESILAHRGP TAHPIGVGNP PIGE
Length:1,124
Mass (Da):120,951
Last modified:May 1, 2000 - v1
Checksum:i92F311862484783D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1124 – 11241Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017790 mRNA. Translation: BAA84774.1.
UniGeneiRn.10025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017790 mRNA. Translation: BAA84774.1.
UniGeneiRn.10025.

3D structure databases

ProteinModelPortaliQ9R0T2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

RGDi2180. Atp7b.

Phylogenomic databases

HOVERGENiHBG050616.

Enzyme and pathway databases

ReactomeiREACT_345620. Ion transport by P-type ATPases.

Gene expression databases

ExpressionAtlasiQ9R0T2. baseline.
GenevestigatoriQ9R0T2.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
IPR006122. HMA_Cu_ion-bd.
IPR027256. P-typ_ATPase_IB.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 5 hits.
PF00702. Hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF55008. SSF55008. 6 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.
TIGR00003. TIGR00003. 5 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 5 hits.
PS50846. HMA_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Further characterization of the rat Atp7b."
    Yamada K., Ijiri T., Yoshida M.C.
    Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: LECImported.

Entry informationi

Entry nameiQ9R0T2_RAT
AccessioniPrimary (citable) accession number: Q9R0T2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: April 1, 2015
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.