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Q9R0S0

- Q9R0S0_MOUSE

UniProt

Q9R0S0 - Q9R0S0_MOUSE

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Protein
Submitted name: GADD45G
Gene
Gadd45g, oig37, mCG_3413
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: MGI

GO - Biological processi

  1. T-helper 1 cell differentiation Source: MGI
  2. activation of MAPKK activity Source: MGI
  3. activation of MAPKKK activity Source: Ensembl
  4. interferon-gamma biosynthetic process Source: MGI
  5. negative regulation of protein kinase activity Source: MGI
  6. positive regulation of JNK cascade Source: Ensembl
  7. positive regulation of apoptotic process Source: Ensembl
  8. positive regulation of p38MAPK cascade Source: Ensembl
  9. regulation of cell cycle Source: MGI
  10. response to stress Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
GADD45GImported
Submitted name:
Growth arrest and DNA damage-inducible protein GADD45 gammaImported
Submitted name:
Growth arrest and DNA-damage-inducible 45 gamma, isoform CRA_bImported
Submitted name:
OIG37Imported
Gene namesi
Name:Gadd45gImported
Synonyms:oig37Imported
ORF Names:mCG_3413Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:1346325. Gadd45g.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9R0S0.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021903.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000016506.
HOVERGENiHBG051684.
InParanoidiQ9R0S0.
KOiK04402.
OMAiDWVPTIT.
OrthoDBiEOG7J1819.
TreeFamiTF300196.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiIPR024824. GADD45.
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
[Graphical view]
PANTHERiPTHR10411. PTHR10411. 1 hit.
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
SUPFAMiSSF55315. SSF55315. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9R0S0-1 [UniParc]FASTAAdd to Basket

« Hide

MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL    50
NVDPDNVTFC VLAADEEDEG DIALQIHFTL IQAFCCENDI DIVRVGDVQR 100
LAAIVGADEE GGAPGDLHCI LISNPNEDTW KDPALEKLSL FCEESRSFND 150
WVPSITLPE 159
Length:159
Mass (Da):17,301
Last modified:May 1, 2000 - v1
Checksum:i4B598AF54529BD96
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126247 Genomic DNA. No translation available.
AY258502 Genomic DNA. Translation: AAP79506.1.
AB021884 mRNA. Translation: BAA78538.1.
CH466546 Genomic DNA. Translation: EDL41110.1.
RefSeqiNP_035947.2. NM_011817.2.
UniGeneiMm.281298.

Genome annotation databases

EnsembliENSMUST00000021903; ENSMUSP00000021903; ENSMUSG00000021453.
GeneIDi23882.
KEGGimmu:23882.
UCSCiuc007qmq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126247 Genomic DNA. No translation available.
AY258502 Genomic DNA. Translation: AAP79506.1 .
AB021884 mRNA. Translation: BAA78538.1 .
CH466546 Genomic DNA. Translation: EDL41110.1 .
RefSeqi NP_035947.2. NM_011817.2.
UniGenei Mm.281298.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000021903.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000021903 ; ENSMUSP00000021903 ; ENSMUSG00000021453 .
GeneIDi 23882.
KEGGi mmu:23882.
UCSCi uc007qmq.2. mouse.

Organism-specific databases

CTDi 10912.
MGIi MGI:1346325. Gadd45g.

Phylogenomic databases

GeneTreei ENSGT00390000016506.
HOVERGENi HBG051684.
InParanoidi Q9R0S0.
KOi K04402.
OMAi DWVPTIT.
OrthoDBi EOG7J1819.
TreeFami TF300196.

Miscellaneous databases

ChiTaRSi GADD45G. mouse.
NextBioi 303623.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9R0S0.

Family and domain databases

Gene3Di 3.30.1330.30. 1 hit.
InterProi IPR024824. GADD45.
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
[Graphical view ]
PANTHERi PTHR10411. PTHR10411. 1 hit.
Pfami PF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view ]
SUPFAMi SSF55315. SSF55315. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth."
    Nakayama K., Hara T., Hibi M., Hirano T., Miyajima A.
    J. Biol. Chem. 274:24766-24772(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "Comparative Analysis of the Genetic Structure and Chromosomal Mapping of the Murine Gadd45g/CR6 Gene."
    Balliet A.G., Hollander M.C., Fornace A.J. Jr., Hoffman B., Liebermann D.A.
    Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129/SvImported.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  6. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ9R0S0_MOUSE
AccessioniPrimary (citable) accession number: Q9R0S0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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