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Protein
Submitted name:

Cytochrome P450 2A15

Gene

CYP2A15

Organism
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 2A15Imported (EC:1.14.14.1Imported)
Gene namesi
Name:CYP2A15Imported
ORF Names:H671_21128Imported
OrganismiCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)Imported
Taxonomic identifieri10029 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaCricetidaeCricetinaeCricetulus
Proteomesi
  • UP000030759 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2419HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG015789.
KOiK17685.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9R0R6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGSELLLVA ILAYLSVMVL VSVWKQKVRG KLPPGPTPLP YIGNYLQLNT
60 70 80 90 100
KDMYSSITEL SERYGPVFTI HLGPRPVVVL YGYDAVKEAL VDQAEEFSGR
110 120 130 140 150
GEQATYNTLF KGYGVTFSSG ERAKQLRRFS IATLRDFGVG KRSVEERIQE
160 170 180 190 200
EAACLVKMLQ STSGAPIDPT VYLSQTVSNV INSIVFGDRF DYEDKEFLEL
210 220 230 240 250
LRMMGQINRF AASPTGQLYD MFHSVMKYLP GPQQQIIKNT KELEDFMVRK
260 270 280 290 300
VKQNQSTLDL NSPRNFIDSF LIHMQEEKKN PDSEFNIQNL VMTSLNLFFA
310 320 330 340 350
GSETVSSTMR YGFLLLMKYP EVEAKVHEEI DRVIGRNRQP QFEDRMKMPY
360 370 380 390 400
TEAVINEIQR FANLAPLGIP RKTIQNTTFR GFFLPKDTEV FPILGSLLTD
410 420 430 440 450
PKFFPSPKDF NPQNFLDDKG QLKKNAAFVP FSVGKRFCLG DGLARMELFL
460 470 480 490
FFTTILQNFR FKFPKKPEDI DESPKPLGFA RIIPHYTMSF LPI
Length:493
Mass (Da):56,330
Last modified:May 1, 2000 - v1
Checksum:i15A341C223A8F520
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022916 mRNA. Translation: BAA83589.1.
KE687042 Genomic DNA. Translation: ERE60255.1.
RefSeqiNP_001230952.1. NM_001244023.1.

Genome annotation databases

GeneIDi100689035.
KEGGicge:100689035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB022916 mRNA. Translation: BAA83589.1.
KE687042 Genomic DNA. Translation: ERE60255.1.
RefSeqiNP_001230952.1. NM_001244023.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100689035.
KEGGicge:100689035.

Organism-specific databases

CTDi100689035.

Phylogenomic databases

HOVERGENiHBG015789.
KOiK17685.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008067. Cyt_P450_E_grp-I_CYP2A-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01684. EP450ICYP2A.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and expression analysis of a new member of the cytochrome P450, CYP2A15 from the Chinese hamster, encoding testosterone 7alpha-hydroxylase."
    Kurose K., Isozaki E., Tohkin M., Fukuhara M.
    Arch. Biochem. Biophys. 371:270-276(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 17A/GYImported.
  3. "Chinese hamster genome sequenced from sorted chromosomes."
    Brinkrolf K., Rupp O., Laux H., Kollin F., Ernst W., Linke B., Kofler R., Romand S., Hesse F., Budach W.E., Galosy S., Muller D., Noll T., Wienberg J., Jostock T., Leonard M., Grillari J., Tauch A.
    , Goesmann A., Helk B., Mott J.E., Puehler A., Borth N.
    Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 17A/GYImported.

Entry informationi

Entry nameiQ9R0R6_CRIGR
AccessioniPrimary (citable) accession number: Q9R0R6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 6, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.