Unreviewed, UniProtKB/TrEMBL Q9R0P8 (Q9R0P8_MOUSE)

Names and origin

Protein names

Submitted name:
    P/Q-type calcium channel alpha1A subunit EMBL BAA84110.1

Gene names

Name:

Cacna1a MGI 109482

Organism

Mus musculus (Mouse) EMBL BAA84110.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	100 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	adult walking behavior Inferred from genetic interaction. Source: MGI behavioral response to pain Inferred from mutant phenotype. Source: MGI calcium ion transport Inferred from mutant phenotype. Source: MGI calcium ion-dependent exocytosis Inferred from mutant phenotype. Source: MGI calcium ion-dependent exocytosis of neurotransmitter Inferred from mutant phenotype. Source: MGI cell growth Inferred from mutant phenotype. Source: MGI cellular chloride ion homeostasis Inferred from mutant phenotype. Source: MGI central nervous system neuron differentiation Inferred from mutant phenotype. Source: MGI cerebellar Purkinje cell differentiation Inferred from mutant phenotype. Source: MGI cerebellar molecular layer development Inferred from mutant phenotype. Source: MGI cerebellum maturation Inferred from mutant phenotype. Source: MGI dendrite morphogenesis Inferred from mutant phenotype. Source: MGI elevation of cytosolic calcium ion concentration Inferred from direct assay. Source: MGI gamma-aminobutyric acid secretion Inferred from mutant phenotype. Source: MGI gamma-aminobutyric acid signaling pathway Inferred from mutant phenotype. Source: MGI glucose metabolic process Inferred from mutant phenotype. Source: MGI hormone metabolic process Inferred from mutant phenotype. Source: MGI membrane depolarization Inferred from mutant phenotype. Source: MGI musculoskeletal movement, spinal reflex action Inferred from mutant phenotype. Source: MGI negative regulation of hormone biosynthetic process Inferred from mutant phenotype. Source: MGI negative regulation of neuron apoptosis Inferred from mutant phenotype. Source: MGI neuromuscular process controlling balance Inferred from mutant phenotype. Source: MGI neuromuscular synaptic transmission Inferred from mutant phenotype. Source: MGI neurotransmitter metabolic process Inferred from mutant phenotype. Source: MGI receptor clustering Inferred from mutant phenotype. Source: MGI regulation of acetylcholine secretion Inferred from mutant phenotype. Source: MGI regulation of axonogenesis Inferred from mutant phenotype. Source: MGI regulation of calcium ion-dependent exocytosis Inferred from direct assay. Source: MGI rhythmic synaptic transmission Inferred from mutant phenotype. Source: MGI spinal cord motor neuron differentiation Inferred from mutant phenotype. Source: MGI sulfur amino acid metabolic process Inferred from mutant phenotype. Source: MGI synapse assembly Inferred from mutant phenotype. Source: MGI synaptic transmission, glutamatergic Inferred from mutant phenotype. Source: MGI vestibular nucleus development Inferred from mutant phenotype. Source: MGI
Cellular component	cell soma Inferred from direct assay. Source: MGI dendrite Inferred from direct assay. Source: MGI voltage-gated calcium channel complex Inferred from direct assay. Source: MGI
Molecular function	high voltage-gated calcium channel activity Inferred from genetic interaction. Source: MGI protein binding Inferred from physical interaction. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	100	1	EMBL BAA84110.1

Sequences

	Sequence		Length	Mass (Da)
	Q9R0P8-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 5AA3183650EAC05F	FASTA	100	10,549
	10 20 30 40 50 60 MARFGDEMPG RYGAGGGGSG PAAGVVVGAA GGRGAGGSRQ GGQPGAQRMY KQSMAQRART 70 80 90 100 MALYNPIPVR QNCLTVNRSL FLFSEDNVVR KYAKKITEWP

References

[1]

"Isolation and functional characterization of the 5'-upstream region of mouse P/Q-type Ca2+ channel alpha1A subunit gene." Takahashi E., Murata Y., Oki T., Miyamoto N., Mori Y., Takada N., Wanifuchi H., Wanifuchi N., Yagami K., Niidome T., Tanaka I., Katayama K. Biochem. Biophys. Res. Commun. 260:54-59(1999) [PubMed: 10381343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CBA EMBL BAA84110.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB025352 Genomic DNA. Translation: BAA84110.1.
IPI	IPI00408646.
UniGene	Mm.334658
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9R0P8.
Genome annotation databases
Ensembl	ENSMUST00000038122; ENSMUSP00000039351; ENSMUSG00000034656; Mus musculus. [Genome view] ENSMUST00000121390; ENSMUSP00000112436; ENSMUSG00000034656; Mus musculus. [Genome view] ENSMUST00000122053; ENSMUSP00000114055; ENSMUSG00000034656; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:109482. Cacna1a.
Phylogenomic databases
HOVERGEN	Q9R0P8.
Gene expression databases
ArrayExpress	Q9R0P8.
Bgee	Q9R0P8.
Genevestigator	Q9R0P8.
Family and domain databases
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q9R0P8_MOUSE

Accession

Primary (citable) accession number: Q9R0P8

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	November 3, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)