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Q9R0P1

- Q9R0P1_MOUSE

UniProt

Q9R0P1 - Q9R0P1_MOUSE

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Protein
Submitted name:

LKB1 serine/threonin kinase

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: Ensembl
  2. magnesium ion binding Source: Ensembl
  3. protein kinase activator activity Source: Ensembl
  4. protein serine/threonine kinase activity Source: Ensembl

GO - Biological processi

  1. activation of protein kinase activity Source: Ensembl
  2. anoikis Source: Ensembl
  3. axonogenesis Source: Ensembl
  4. cell cycle arrest Source: Ensembl
  5. intrinsic apoptotic signaling pathway by p53 class mediator Source: Ensembl
  6. negative regulation of cell proliferation Source: Ensembl
  7. positive regulation of gluconeogenesis Source: Ensembl
  8. positive regulation of transforming growth factor beta receptor signaling pathway Source: Ensembl
  9. protein autophosphorylation Source: Ensembl
  10. protein heterooligomerization Source: Ensembl
  11. response to glucagon Source: Ensembl
  12. response to lipid Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
LKB1 serine/threonin kinaseImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: Ensembl
  2. nucleus Source: Ensembl
  3. protein complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ9R0P1.
BgeeiQ9R0P1.
GenevestigatoriQ9R0P1.

Structurei

3D structure databases

ProteinModelPortaliQ9R0P1.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotations

Phylogenomic databases

HOVERGENiHBG054467.
InParanoidiQ9R0P1.

Family and domain databases

InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9R0P1-1 [UniParc]FASTAAdd to Basket

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EIQLLRRLRH RNVIQLVDVL YNEEKQKMYM VMEYCVCGMQ EMLDSVPEKR    50
FPVCQAHGYF RQLIDGLEYL HSQGIVHKDI KPGNLLLTTN GTLKISDLGV 100
AEALHPFAVD DTCRTSQGSP AFQPPEIANG LDTFSGFKVD IWSAGVTLYN 150
ITTGLYPFEG DNIYKLFENI GRGDFTIPCD CGPPLSDLLR GMLEYEPAKR 200
FSIRQIRQHS WFRKKHPLAE ALVPIPPSPD TKDRWRSMTV VPYLEDLHGR 250
AEEEEEEDLF DIEDGIIYTQ DFTVPGQVLE EEVGQNGQSH SLPKAVCVNG 300
TEPQLSSKVK PEGRPGTANP ARKVCSSNKI RRLSACKQQ 339
Length:339
Mass (Da):38,308
Last modified:May 1, 2000 - v1
Checksum:i73F4DB9438443A6C
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026255 Genomic DNA. Translation: BAA86229.1.
UniGeneiMm.44231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB026255 Genomic DNA. Translation: BAA86229.1 .
UniGenei Mm.44231.

3D structure databases

ProteinModelPortali Q9R0P1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG054467.
InParanoidi Q9R0P1.

Gene expression databases

ArrayExpressi Q9R0P1.
Bgeei Q9R0P1.
Genevestigatori Q9R0P1.

Family and domain databases

InterProi IPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
PANTHERi PTHR24347. PTHR24347. 1 hit.
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129OlaImported.

Entry informationi

Entry nameiQ9R0P1_MOUSE
AccessioniPrimary (citable) accession number: Q9R0P1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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