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Protein

UDP-galactose translocator

Gene

Slc35a2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.

GO - Molecular functioni

  • UDP-galactose transmembrane transporter activity Source: MGI

GO - Biological processi

  • carbohydrate transport Source: UniProtKB-KW
  • UDP-galactose transmembrane transport Source: MGI

Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-727802 Transport of nucleotide sugars

Protein family/group databases

TCDBi2.A.7.12.8 the drug/metabolite transporter (dmt) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-galactose translocator
Alternative name(s):
Solute carrier family 35 member A2
UDP-galactose transporter
Short name:
UDP-Gal-Tr
Short name:
UGT
Short name:
mUGT1
Gene namesi
Name:Slc35a2
Synonyms:Ugt1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1345297 Slc35a2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei37 – 57HelicalSequence analysisAdd BLAST21
Transmembranei65 – 85HelicalSequence analysisAdd BLAST21
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Transmembranei140 – 160HelicalSequence analysisAdd BLAST21
Transmembranei169 – 189HelicalSequence analysisAdd BLAST21
Transmembranei200 – 220HelicalSequence analysisAdd BLAST21
Transmembranei238 – 258HelicalSequence analysisAdd BLAST21
Transmembranei269 – 289HelicalSequence analysisAdd BLAST21
Transmembranei315 – 335HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002133541 – 390UDP-galactose translocatorAdd BLAST390

Proteomic databases

MaxQBiQ9R0M8
PaxDbiQ9R0M8
PRIDEiQ9R0M8

PTM databases

iPTMnetiQ9R0M8
PhosphoSitePlusiQ9R0M8
SwissPalmiQ9R0M8

Expressioni

Gene expression databases

BgeeiENSMUSG00000031156
ExpressionAtlasiQ9R0M8 baseline and differential
GenevisibleiQ9R0M8 MM

Interactioni

Subunit structurei

Interacts with SLC35A3.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000111327

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2234 Eukaryota
COG0697 LUCA
GeneTreeiENSGT00550000074563
HOVERGENiHBG054025
InParanoidiQ9R0M8
KOiK15272

Family and domain databases

InterProiView protein in InterPro
IPR007271 Nuc_sug_transpt
PANTHERiPTHR10231 PTHR10231, 1 hit
PfamiView protein in Pfam
PF04142 Nuc_sug_transp, 1 hit
PIRSFiPIRSF005799 UDP-gal_transpt, 1 hit

Sequencei

Sequence statusi: Complete.

Q9R0M8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVGVGGST AAAGAGAVSS GALEPGSTTA AHRRLKYISL AVLVVQNASL
60 70 80 90 100
ILSIRYARTL PGDRFFATTA VVMAEVLKGL TCLLLLFAQK RGNVKHLVLF
110 120 130 140 150
LHEAVLVQYV DTLKLAVPSL IYTLQNNLQY VAISNLPAAT FQVTYQLKIL
160 170 180 190 200
TTALFSVLML NRSLSRLQWA SLLLLFTGVA IVQAQQAGGS GPRPLDQNPG
210 220 230 240 250
AGLAAVVASC LSSGFAGVYF EKILKGSSGS VWLRNLQLGL FGTALGLVGL
260 270 280 290 300
WWAEGTAVAS QGFFFGYTPA VWGVVLNQAF GGLLVAVVVK YADNILKGFA
310 320 330 340 350
TSLSIVLSTV ASIRLFGFHL DPLFALGAGL VIGAVYLYSL PRGAVKAIAS
360 370 380 390
ASASGPCIHQ QPPGQPPPPQ LSSRGDLTTE PFLPKSVLVK
Length:390
Mass (Da):40,766
Last modified:May 1, 2000 - v1
Checksum:iF7CD57C5C0D401B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB027147 mRNA Translation: BAA86885.1
BC037701 mRNA Translation: AAH37701.1
CCDSiCCDS52987.1
PIRiJC7162
RefSeqiNP_001077406.1, NM_001083937.1
UniGeneiMm.214976

Genome annotation databases

EnsembliENSMUST00000115660; ENSMUSP00000111324; ENSMUSG00000031156
ENSMUST00000155967; ENSMUSP00000146730; ENSMUSG00000031156
GeneIDi22232
KEGGimmu:22232
UCSCiuc009sna.1 mouse

Similar proteinsi

Entry informationi

Entry nameiS35A2_MOUSE
AccessioniPrimary (citable) accession number: Q9R0M8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 23, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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