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Q9R0K8 (STC2_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Stanniocalcin-2
Short name=STC-2
Gene names
Name:Stc2
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length296 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Has an anti-hypocalcemic action on calcium and phosphate homeostasis.

Subunit structure

Homodimer; disulfide-linked By similarity.

Subcellular location

Secreted Potential.

Tissue specificity

Expressed in a variety of tissues. Strongly expressed in ovary and to a lesser extent in kidney.

Sequence similarities

Belongs to the stanniocalcin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 296272Stanniocalcin-2
PRO_0000033307

Amino acid modifications

Glycosylation731N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9R0K8 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: 0903639858D9B2DC

FASTA29632,622
        10         20         30         40         50         60 
MCAERLGQFV TLALVFATLD PARGTDSTNP PEGPQDRGSQ QKGRLSLQNT AEIQHCLVNA 

        70         80         90        100        110        120 
GDVGCGVFEC FENNSCEIQG LHGICMTFLH NAGKFDAQGK SFIKDALRCK AHALRHKFGC 

       130        140        150        160        170        180 
ISRKCPAIRE MVYQLQRECY LKHDLCSAAQ ENVVVIVEMI HFKDLLLHEP YVDLVNLLLT 

       190        200        210        220        230        240 
CGEDVREAVT RSVQAQCEQS WGGLCSILSF CTSNIQRPPT AAPEHQPLAD RAQLSRPYHR 

       250        260        270        280        290 
DTDHHLTANR GAKGERGSKS HLHAHARGGA GGQSAQGPSG SSEWEDEQSE YSDIRR

« Hide

References

[1]"Regulation by 1alpha,25-dihydroxyvitamin D(3) of expression of stanniocalcin messages in the rat kidney and ovary."
Honda S., Kashiwagi M., Ookata K., Tojo A., Hirose S.
FEBS Lett. 459:119-122(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: Sprague-Dawley.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB030707 mRNA. Translation: BAA85251.1.
IPIIPI00206323.
RefSeqNP_071566.1. NM_022230.2.
UniGeneRn.44823.

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDEQ9R0K8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000028146; ENSRNOP00000028146; ENSRNOG00000020729.
GeneID63878.
KEGGrno:63878.
UCSCRGD:621777. rat.

Organism-specific databases

CTD8614.
RGD621777. Stc2.

Phylogenomic databases

eggNOGNOG44223.
GeneTreeENSGT00390000005989.
HOGENOMHOG000220830.
HOVERGENHBG001048.
InParanoidQ9R0K8.
OMAEYSDIRR.
OrthoDBEOG4KWJT6.

Gene expression databases

GenevestigatorQ9R0K8.
GermOnlineENSRNOG00000020729. Rattus norvegicus.

Family and domain databases

InterProIPR004978. Stanniocalcin.
[Graphical view]
PANTHERPTHR11245. PTHR11245. 1 hit.
PfamPF03298. Stanniocalcin. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio612492.

Entry information

Entry nameSTC2_RAT
AccessionPrimary (citable) accession number: Q9R0K8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 1, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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