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Protein

Single-stranded DNA-binding protein 3

Gene

Ssbp3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.By similarity

GO - Molecular functioni

  • single-stranded DNA binding Source: RGD

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Single-stranded DNA-binding protein 3
Alternative name(s):
Sequence-specific single-stranded-DNA-binding protein
Gene namesi
Name:Ssbp3
Synonyms:Ssdp, Ssdp1, Ssdp3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621502. Ssbp3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Single-stranded DNA-binding protein 3PRO_0000123830Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei320 – 3201PhosphoserineCombined sources
Modified residuei325 – 3251PhosphoserineBy similarity
Modified residuei328 – 3281PhosphoserineBy similarity
Modified residuei333 – 3331PhosphothreonineCombined sources
Modified residuei354 – 3541PhosphoserineBy similarity
Modified residuei360 – 3601PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ9R050.

PTM databases

iPTMnetiQ9R050.
PhosphoSiteiQ9R050.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011408.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 4833LisHPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi98 – 292195Pro-richAdd
BLAST
Compositional biasi110 – 342233Gly-richAdd
BLAST

Sequence similaritiesi

Contains 1 LisH domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4594. Eukaryota.
ENOG410XPQX. LUCA.
HOGENOMiHOG000037785.
HOVERGENiHBG068487.
InParanoidiQ9R050.
PhylomeDBiQ9R050.

Family and domain databases

InterProiIPR006594. LisH.
IPR008116. SSDP_DNA-bd.
[Graphical view]
PRINTSiPR01743. SSDNABINDING.
SMARTiSM00667. LisH. 1 hit.
[Graphical view]
PROSITEiPS50896. LISH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9R050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAKGKGSAV PSDGQAREKL ALYVYEYLLH VGAQKSAQTF LSEIRWEKNI
60 70 80 90 100
TLGEPPGFLH SWWCVFWDLY CAAPERRDTC EHSSEAKAFH DYSAAAAPSP
110 120 130 140 150
VLGNIPPNDG MPGGPIPPGF FQPFMSPRYA GGPRPPIRMG NQPPGGVPGT
160 170 180 190 200
QPLMPNSMDP TRQQGHPNMG GSMQRMNPPR GMGPMGPGPQ NYGSGMRPPP
210 220 230 240 250
NSLGPAMPGI NMGPGAGRPW PNPNSANSIP YSSSSPGTYV GPPGGGGPPG
260 270 280 290 300
TPIMPSPADS TNSSDNIYTM INPVPPGGSR SNFPMGPGSD GPMGGMGGME
310 320 330 340 350
PHHMNGSLGS GDINGLPKNS PNNISGISNP PGTPRDDGEL GGNFLHSFQN
360
DNYSPSMTMS V
Length:361
Mass (Da):37,714
Last modified:May 1, 2000 - v1
Checksum:i7E1AA48EC355B161
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF121893 mRNA. Translation: AAD52710.1.
RefSeqiNP_445810.1. NM_053358.1.
UniGeneiRn.162074.

Genome annotation databases

GeneIDi84354.
KEGGirno:84354.
UCSCiRGD:621502. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF121893 mRNA. Translation: AAD52710.1.
RefSeqiNP_445810.1. NM_053358.1.
UniGeneiRn.162074.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011408.

PTM databases

iPTMnetiQ9R050.
PhosphoSiteiQ9R050.

Proteomic databases

PaxDbiQ9R050.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi84354.
KEGGirno:84354.
UCSCiRGD:621502. rat.

Organism-specific databases

CTDi23648.
RGDi621502. Ssbp3.

Phylogenomic databases

eggNOGiKOG4594. Eukaryota.
ENOG410XPQX. LUCA.
HOGENOMiHOG000037785.
HOVERGENiHBG068487.
InParanoidiQ9R050.
PhylomeDBiQ9R050.

Miscellaneous databases

PROiQ9R050.

Family and domain databases

InterProiIPR006594. LisH.
IPR008116. SSDP_DNA-bd.
[Graphical view]
PRINTSiPR01743. SSDNABINDING.
SMARTiSM00667. LisH. 1 hit.
[Graphical view]
PROSITEiPS50896. LISH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSSBP3_RAT
AccessioniPrimary (citable) accession number: Q9R050
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 10, 2003
Last sequence update: May 1, 2000
Last modified: June 8, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.