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Protein

DnaJ homolog subfamily C member 12

Gene

Dnajc12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Keywordsi

Molecular functionChaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 12
Alternative name(s):
J domain-containing protein 1
Gene namesi
Name:Dnajc12
Synonyms:Jdp1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1353428. Dnajc12.

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000710671 – 198DnaJ homolog subfamily C member 12Add BLAST198

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei160PhosphoserineCombined sources1
Modified residuei166PhosphoserineCombined sources1
Modified residuei182PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9R022.
PaxDbiQ9R022.
PRIDEiQ9R022.

PTM databases

iPTMnetiQ9R022.
PhosphoSitePlusiQ9R022.

Expressioni

Tissue specificityi

Ubiquitous. Highest levels of expression in kidney.

Gene expression databases

BgeeiENSMUSG00000036764.
CleanExiMM_DNAJC12.
ExpressionAtlasiQ9R022. baseline and differential.
GenevisibleiQ9R022. MM.

Interactioni

Subunit structurei

Interacts with HSPA8.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041298.

Structurei

3D structure databases

ProteinModelPortaliQ9R022.
SMRiQ9R022.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 79JPROSITE-ProRule annotationAdd BLAST66

Phylogenomic databases

eggNOGiKOG0691. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00550000074688.
HOGENOMiHOG000017161.
HOVERGENiHBG051379.
InParanoidiQ9R022.
KOiK09532.
OMAiTSMHWAV.
OrthoDBiEOG091G0UTL.
PhylomeDBiQ9R022.
TreeFamiTF105171.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR001623. DnaJ_domain.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiView protein in PROSITE
PS50076. DNAJ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9R022-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAILNYRPE GSEDYYALLG CDELSSVEQI LAEFKIRALE CHPDKHPENS
60 70 80 90 100
KAVETFQKLQ KAKEILCNAE SRARYDHWRR SQMSMPFEQW EALADSVKTS
110 120 130 140 150
MHWAVRSKKD LMLEGSGQTF TSSVPNKERS EQRETKKGDP DSNPEKMKQK
160 170 180 190
EPKFPEEGIS PQNPDSPGLS DLNCGHLRFR WSGDAPSELL RKFRNYEI
Length:198
Mass (Da):22,853
Last modified:May 1, 2000 - v1
Checksum:iBF7583D399495240
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF132906 mRNA. Translation: AAD48756.2.
BC013501 mRNA. Translation: AAH13501.1.
CCDSiCCDS23899.1.
RefSeqiNP_038916.1. NM_013888.3.
UniGeneiMm.32550.

Genome annotation databases

EnsembliENSMUST00000043317; ENSMUSP00000041298; ENSMUSG00000036764.
GeneIDi30045.
KEGGimmu:30045.
UCSCiuc007fkg.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiDJC12_MOUSE
AccessioniPrimary (citable) accession number: Q9R022
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: May 1, 2000
Last modified: August 30, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot