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Protein

DnaJ homolog subfamily C member 12

Gene

Dnajc12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 12
Alternative name(s):
J domain-containing protein 1
Gene namesi
Name:Dnajc12
Synonyms:Jdp1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1353428. Dnajc12.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198DnaJ homolog subfamily C member 12PRO_0000071067Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei160 – 1601PhosphoserineCombined sources
Modified residuei166 – 1661PhosphoserineCombined sources
Modified residuei182 – 1821PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9R022.
PaxDbiQ9R022.
PRIDEiQ9R022.

PTM databases

iPTMnetiQ9R022.
PhosphoSiteiQ9R022.

Expressioni

Tissue specificityi

Ubiquitous. Highest levels of expression in kidney.

Gene expression databases

BgeeiQ9R022.
CleanExiMM_DNAJC12.
ExpressionAtlasiQ9R022. baseline and differential.
GenevisibleiQ9R022. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041298.

Structurei

3D structure databases

ProteinModelPortaliQ9R022.
SMRiQ9R022. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 7966JPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 J domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0691. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00550000074688.
HOGENOMiHOG000017161.
HOVERGENiHBG051379.
InParanoidiQ9R022.
KOiK09532.
OMAiYWHLRFR.
PhylomeDBiQ9R022.
TreeFamiTF105171.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9R022-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAILNYRPE GSEDYYALLG CDELSSVEQI LAEFKIRALE CHPDKHPENS
60 70 80 90 100
KAVETFQKLQ KAKEILCNAE SRARYDHWRR SQMSMPFEQW EALADSVKTS
110 120 130 140 150
MHWAVRSKKD LMLEGSGQTF TSSVPNKERS EQRETKKGDP DSNPEKMKQK
160 170 180 190
EPKFPEEGIS PQNPDSPGLS DLNCGHLRFR WSGDAPSELL RKFRNYEI
Length:198
Mass (Da):22,853
Last modified:May 1, 2000 - v1
Checksum:iBF7583D399495240
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF132906 mRNA. Translation: AAD48756.2.
BC013501 mRNA. Translation: AAH13501.1.
CCDSiCCDS23899.1.
RefSeqiNP_038916.1. NM_013888.3.
UniGeneiMm.32550.

Genome annotation databases

EnsembliENSMUST00000043317; ENSMUSP00000041298; ENSMUSG00000036764.
GeneIDi30045.
KEGGimmu:30045.
UCSCiuc007fkg.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF132906 mRNA. Translation: AAD48756.2.
BC013501 mRNA. Translation: AAH13501.1.
CCDSiCCDS23899.1.
RefSeqiNP_038916.1. NM_013888.3.
UniGeneiMm.32550.

3D structure databases

ProteinModelPortaliQ9R022.
SMRiQ9R022. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041298.

PTM databases

iPTMnetiQ9R022.
PhosphoSiteiQ9R022.

Proteomic databases

MaxQBiQ9R022.
PaxDbiQ9R022.
PRIDEiQ9R022.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043317; ENSMUSP00000041298; ENSMUSG00000036764.
GeneIDi30045.
KEGGimmu:30045.
UCSCiuc007fkg.2. mouse.

Organism-specific databases

CTDi56521.
MGIiMGI:1353428. Dnajc12.

Phylogenomic databases

eggNOGiKOG0691. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00550000074688.
HOGENOMiHOG000017161.
HOVERGENiHBG051379.
InParanoidiQ9R022.
KOiK09532.
OMAiYWHLRFR.
PhylomeDBiQ9R022.
TreeFamiTF105171.

Miscellaneous databases

NextBioi307140.
PROiQ9R022.
SOURCEiSearch...

Gene expression databases

BgeeiQ9R022.
CleanExiMM_DNAJC12.
ExpressionAtlasiQ9R022. baseline and differential.
GenevisibleiQ9R022. MM.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of phylogenetically conserved J domain protein gene."
    Hahn Y., Lee J., Seong C., Yoon J., Chung J.H.
    Biochim. Biophys. Acta 1447:325-333(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-160; SER-166 AND SER-182, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Kidney and Pancreas.

Entry informationi

Entry nameiDJC12_MOUSE
AccessioniPrimary (citable) accession number: Q9R022
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: May 1, 2000
Last modified: May 11, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.