Afadin - Mus musculus (Mouse)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Afadin

Alternative name(s):
Protein Af-6

Gene names

Name:	Mllt4
Synonyms:	Af6

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1820 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm. Ref.2
Subunit structure	Homodimer. Interacts with F-actin, nectin and PVRL3/nectin-3. Essential for the association of nectin and E-cadherin. Isoform 2/s-afadin does not interact with F-actin. Interacts with ZO-1 and occludin, but probably in an indirect manner. Interacts with RIT1, RIT2, NRXN1 and BCR By similarity. Ref.4
Subcellular location	Cell junction › adherens junction. Note: Not found at cell-matrix AJs.
Tissue specificity	Isoform 1 is expressed only in a restricted set of epithelial structures during early embryogenesis. Ref.2
Developmental stage	Highly expressed at restricted set of epithelial structures and highly concentrated at their junctional complex regions. At E6.5, localized at the most apical regions of cell-cell adhesion sites of the entire embryonic ectoderm; not detected in the extraembryonic regions. At E7.0, expressed in the primitive streak and the migrating paraxial mesoderm. At E7.5, highly expressed at the junctional complex regions in the primitive streak region (neuroepithelium) and the neural fold/grove region, but hardly detected in other areas of the ectoderm. By E8.5, highly expressed in the tail bud, somites and the paraxial mesoderm, concentrated at the junctional complex regions in neural tube, somites and pericardioperitoneal canal. Ref.2
Disruption phenotype	Mice show developmental defects at stages during and after gastrulation, including disorganization of the ectoderm, impaired migration of the mesoderm and loss of somites and other structures derived from both the ectoderm and mesoderm. Cell-cell adherens juntions and tight junctions are improperly organized in the ectoderm-derived cells. No redundancy exists in the function of afadin during gastrulation. Ref.2
Sequence similarities	Contains 1 dilute domain. Contains 1 FHA domain. Contains 1 PDZ (DHR) domain. Contains 2 Ras-associating domains.

Ontologies

Keywords
Biological process	Cell adhesion
Cellular component	Cell junction
Coding sequence diversity	Alternative splicing
Domain	Coiled coil Repeat
PTM	Phosphoprotein
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	apical part of cell Inferred from direct assay PubMed 10704870. Source: MGI cell-cell adherens junction Inferred from direct assay PubMed 11731229 PubMed 15728677. Source: MGI cytoplasm Inferred from direct assay PubMed 15509704 PubMed 22027834. Source: MGI nucleus Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 3 (identifier: Q9QZQ1-3) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 1 (identifier: Q9QZQ1-2) Also known as: l-afadin; The sequence of this isoform differs from the canonical sequence as follows: 393-407: Missing.

Isoform 2 (identifier: Q9QZQ1-1) Also known as: s-afadin; The sequence of this isoform is not available.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 1820

1820

Afadin

PRO_0000215919

Regions

Domain

39 – 133

95

Ras-associating 1

Domain

246 – 348

103

Ras-associating 2

Domain

426 – 492

67

FHA

Domain

653 – 908

256

Dilute

Domain

1007 – 1093

87

PDZ

Coiled coil

146 – 186

41

Potential

Coiled coil

1410 – 1446

37

Potential

Coiled coil

1523 – 1561

39

Potential

Coiled coil

1593 – 1665

73

Potential

Compositional bias

163 – 175

13

Glu/Lys-rich

Compositional bias

1346 – 1392

47

Pro-rich

Compositional bias

1676 – 1706

31

Pro-rich

Compositional bias

1733 – 1736

4

Poly-Glu

Amino acid modifications

Modified residue

216

1

Phosphoserine By similarity

Modified residue

557

1

Phosphoserine By similarity

Modified residue

1107

1

Phosphoserine Ref.5 Ref.6

Modified residue

1172

1

Phosphoserine By similarity

Modified residue

1173

1

Phosphoserine By similarity

Modified residue

1182

1

Phosphoserine Ref.5 Ref.6

Modified residue

1232

1

Phosphothreonine By similarity

Modified residue

1275

1

Phosphoserine Ref.5

Modified residue

1330

1

Phosphothreonine By similarity

Modified residue

1334

1

Phosphothreonine By similarity

Modified residue

1719

1

Phosphoserine By similarity

Modified residue

1795

1

Phosphoserine By similarity

Natural variations

Alternative sequence

393 – 407

15

Missing in isoform 1.

VSP_026731

Experimental info

Sequence conflict

23

1

N → Y in AAD54283. Ref.2

Sequence conflict

101

1

E → EE in AK016557. Ref.3

Sequence conflict

694

1

N → D in AK016557. Ref.3

Sequence conflict

897 – 900

4

DLIE → PEMR in AK016557. Ref.3

Secondary structure

1

.

1820

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

Isoform 3 [UniParc].

Last modified July 10, 2007. Version 3.
Checksum: 9FA4F378D840D8B1
Show »

FASTA

1,820

206,499

        10         20         30         40         50         60 
MSAGGRDEER RKLADIIHHW NANRLDLFEI SQPTEDLEFH GVMRFYFQDK AAGNFATKCI 

        70         80         90        100        110        120 
RVSSTATTQD VIETLAEKFR PDMRMLSSPK YSLYEVHVSG ERRLDIDEKP LVVQLNWNKD 

       130        140        150        160        170        180 
DREGRFVLKN ENDAIPAKKA QSNGPEKQEK EGVIQNFKRT LSKKEKKEKK KKEKEALRQA 

       190        200        210        220        230        240 
SDKEERPSQG DDSENSRLAA EVYKDMPETS FTRTISNPEV VMKRRRQQKL EKRMQEFRSS 

       250        260        270        280        290        300 
DGRPDSGGTL RIYADSLKPN IPYKTILLST TDTADFAVAE SLEKYGLEKE NPKDYCIARV 

       310        320        330        340        350        360 
MLPPGAQHSD ERGAKEIILD DDECPLQIFR EWPSDKGILV FQLKRRPPDY IPKKMKKHVE 

       370        380        390        400        410        420 
GKSLKGKDRA DGSGYGSALP PEKLPYLVEL SPGRRNHFAY YSYHTYEDGS DSRDKPKLYR 

       430        440        450        460        470        480 
LQLSVTEVGT EKFDDNSIQL FGPGIQPHHC DLTNMDGVVT VTPRSMDAET YVDGQRISET 

       490        500        510        520        530        540 
TMLQSGMRLQ FGTSHVFKFV DPIQDHVLSK RSVDGGLMVK GPRHKPGAVQ ETTFELGGDV 

       550        560        570        580        590        600 
HSGTALPASR STTRLDSDRV SSASSTAERG MVKPMIRLDQ EQEYRRRENR TQDATGPELI 

       610        620        630        640        650        660 
LPASIEFRES SEDSFLSAII NYTNSSTVHF KLSPTYVLYM ACRYVLSSQH RPDISPTERT 

       670        680        690        700        710        720 
HKAIAVVNKM VSMMEGVIQK QKNIAGALAF WMANASELLN FIKQDRDLSR ITLDAQDVLA 

       730        740        750        760        770        780 
HLVQMAFKYL VHCLQSELNN YMPAFLDDPE ENSLQRPKID DVLHTLTGAM SLLRRCRVNA 

       790        800        810        820        830        840 
ALTIQLFSQL FHFINMWLFN RLVTDPDSGL CSHYWGAIIR QQLGHIEAWA EKQGLELAAD 

       850        860        870        880        890        900 
CHLSRIVQAT TLLTMDKYVP DDIPNINSTC FKLNSLQLQA LLQNYHCAPD EPFIPTDLIE 

       910        920        930        940        950        960 
NVVAVAENTA DELARSDGRD VQLEEDPDLQ LPFLLPEDGY SCDVVRNIPN GLQEFLDPLC 

       970        980        990       1000       1010       1020 
QRGFCRLVPH TRSPGTWTIY FEGADYESHL MRENAELAQP LRKEPEIITV TLKKQNGMGL 

      1030       1040       1050       1060       1070       1080 
SIVAAKGAGQ DKLGIYVKSV VKGGAADVDG RLAAGDQLLS VDGRSLVGLS QERAAELMTR 

      1090       1100       1110       1120       1130       1140 
TSSVVTLEVA KQGAIYHGLA TLLNQPSPMM QRISDRRGSG KPRPKSEGFE LYNNSAQNGS 

      1150       1160       1170       1180       1190       1200 
PESPQMPWTE YSEPKKLPGD DRLMKNRADH RSSPNVANQP PSPGGKGPYT SGTAAKITSV 

      1210       1220       1230       1240       1250       1260 
STGNLCTEEQ SPPPRPEAYP IPTQTYTREY FTFPASKSQD RMAPPQSQWP NYEEKPHVHT 

      1270       1280       1290       1300       1310       1320 
ESNHSSIAIQ RVTRSQEELR EEKVYQLERH RVEAGMDRKC DSDMWINQSS SVESSTSSQE 

      1330       1340       1350       1360       1370       1380 
HLNHSSKSVT PASTLTKSGP GRWKTPAAVL PTPVAVSQPI RTDLPPPPPP PPVHYTSEFD 

      1390       1400       1410       1420       1430       1440 
GIPMDLPLPP PPANQAGPQS AQVAAAEWKK REEHQRWYEK EKARLEEERE RKRREQERKL 

      1450       1460       1470       1480       1490       1500 
GQMRSQTLNP ASFSPLATQA KPEKPSTLQR PQETVIRELQ PQQQPRTIER KDLQYITISK 

      1510       1520       1530       1540       1550       1560 
EELSSGDSLS PDPWKRDARE KLEKQQQMHI VDMLSKEIHE LQNKVDRTAE ESDRLRKLML 

      1570       1580       1590       1600       1610       1620 
EWQFQKRLQE SKQKDEDDDE EEDDDVDTML IMQRLEAERR ARMQDEERRR QQQLEEMRKR 

      1630       1640       1650       1660       1670       1680 
EAEDRVRQEE DGRHQEEERV KRDAEEKRRQ EEGYYSRLEA ERRRQHEEAA RRLLEPEEPG 

      1690       1700       1710       1720       1730       1740 
LSRPPLPRDY EPPSLSSAPC APPPPPQRNA SYLKTQVLSP DSLFTAKFVA YDEEEEDYGP 

      1750       1760       1770       1780       1790       1800 
AGPNSYSGSA GTAVGAYDAP REAREKLTRS QDADLPGSSG APENLTFKER QRLFSQGQDV 

      1810       1820 
SDKVKASRKL TELENELNTK

« Hide

Isoform 1 (l-afadin) [UniParc].

Checksum: 5987A16BA9F28C2E
Show »

FASTA

1,805

204,553

        10         20         30         40         50         60 
MSAGGRDEER RKLADIIHHW NANRLDLFEI SQPTEDLEFH GVMRFYFQDK AAGNFATKCI 

        70         80         90        100        110        120 
RVSSTATTQD VIETLAEKFR PDMRMLSSPK YSLYEVHVSG ERRLDIDEKP LVVQLNWNKD 

       130        140        150        160        170        180 
DREGRFVLKN ENDAIPAKKA QSNGPEKQEK EGVIQNFKRT LSKKEKKEKK KKEKEALRQA 

       190        200        210        220        230        240 
SDKEERPSQG DDSENSRLAA EVYKDMPETS FTRTISNPEV VMKRRRQQKL EKRMQEFRSS 

       250        260        270        280        290        300 
DGRPDSGGTL RIYADSLKPN IPYKTILLST TDTADFAVAE SLEKYGLEKE NPKDYCIARV 

       310        320        330        340        350        360 
MLPPGAQHSD ERGAKEIILD DDECPLQIFR EWPSDKGILV FQLKRRPPDY IPKKMKKHVE 

       370        380        390        400        410        420 
GKSLKGKDRA DGSGYGSALP PEKLPYLVEL SPDGSDSRDK PKLYRLQLSV TEVGTEKFDD 

       430        440        450        460        470        480 
NSIQLFGPGI QPHHCDLTNM DGVVTVTPRS MDAETYVDGQ RISETTMLQS GMRLQFGTSH 

       490        500        510        520        530        540 
VFKFVDPIQD HVLSKRSVDG GLMVKGPRHK PGAVQETTFE LGGDVHSGTA LPASRSTTRL 

       550        560        570        580        590        600 
DSDRVSSASS TAERGMVKPM IRLDQEQEYR RRENRTQDAT GPELILPASI EFRESSEDSF 

       610        620        630        640        650        660 
LSAIINYTNS STVHFKLSPT YVLYMACRYV LSSQHRPDIS PTERTHKAIA VVNKMVSMME 

       670        680        690        700        710        720 
GVIQKQKNIA GALAFWMANA SELLNFIKQD RDLSRITLDA QDVLAHLVQM AFKYLVHCLQ 

       730        740        750        760        770        780 
SELNNYMPAF LDDPEENSLQ RPKIDDVLHT LTGAMSLLRR CRVNAALTIQ LFSQLFHFIN 

       790        800        810        820        830        840 
MWLFNRLVTD PDSGLCSHYW GAIIRQQLGH IEAWAEKQGL ELAADCHLSR IVQATTLLTM 

       850        860        870        880        890        900 
DKYVPDDIPN INSTCFKLNS LQLQALLQNY HCAPDEPFIP TDLIENVVAV AENTADELAR 

       910        920        930        940        950        960 
SDGRDVQLEE DPDLQLPFLL PEDGYSCDVV RNIPNGLQEF LDPLCQRGFC RLVPHTRSPG 

       970        980        990       1000       1010       1020 
TWTIYFEGAD YESHLMRENA ELAQPLRKEP EIITVTLKKQ NGMGLSIVAA KGAGQDKLGI 

      1030       1040       1050       1060       1070       1080 
YVKSVVKGGA ADVDGRLAAG DQLLSVDGRS LVGLSQERAA ELMTRTSSVV TLEVAKQGAI 

      1090       1100       1110       1120       1130       1140 
YHGLATLLNQ PSPMMQRISD RRGSGKPRPK SEGFELYNNS AQNGSPESPQ MPWTEYSEPK 

      1150       1160       1170       1180       1190       1200 
KLPGDDRLMK NRADHRSSPN VANQPPSPGG KGPYTSGTAA KITSVSTGNL CTEEQSPPPR 

      1210       1220       1230       1240       1250       1260 
PEAYPIPTQT YTREYFTFPA SKSQDRMAPP QSQWPNYEEK PHVHTESNHS SIAIQRVTRS 

      1270       1280       1290       1300       1310       1320 
QEELREEKVY QLERHRVEAG MDRKCDSDMW INQSSSVESS TSSQEHLNHS SKSVTPASTL 

      1330       1340       1350       1360       1370       1380 
TKSGPGRWKT PAAVLPTPVA VSQPIRTDLP PPPPPPPVHY TSEFDGIPMD LPLPPPPANQ 

      1390       1400       1410       1420       1430       1440 
AGPQSAQVAA AEWKKREEHQ RWYEKEKARL EEERERKRRE QERKLGQMRS QTLNPASFSP 

      1450       1460       1470       1480       1490       1500 
LATQAKPEKP STLQRPQETV IRELQPQQQP RTIERKDLQY ITISKEELSS GDSLSPDPWK 

      1510       1520       1530       1540       1550       1560 
RDAREKLEKQ QQMHIVDMLS KEIHELQNKV DRTAEESDRL RKLMLEWQFQ KRLQESKQKD 

      1570       1580       1590       1600       1610       1620 
EDDDEEEDDD VDTMLIMQRL EAERRARMQD EERRRQQQLE EMRKREAEDR VRQEEDGRHQ 

      1630       1640       1650       1660       1670       1680 
EEERVKRDAE EKRRQEEGYY SRLEAERRRQ HEEAARRLLE PEEPGLSRPP LPRDYEPPSL 

      1690       1700       1710       1720       1730       1740 
SSAPCAPPPP PQRNASYLKT QVLSPDSLFT AKFVAYDEEE EDYGPAGPNS YSGSAGTAVG 

      1750       1760       1770       1780       1790       1800 
AYDAPREARE KLTRSQDADL PGSSGAPENL TFKERQRLFS QGQDVSDKVK ASRKLTELEN 


ELNTK

« Hide

Isoform 2 (s-afadin) (Sequence not available).

–

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[2]	"Afadin: a key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis." Ikeda W., Nakanishi H., Miyoshi J., Mandai K., Ishizaki H., Tanaka M., Togawa A., Takahashi K., Nishioka H., Yoshida H., Mizoguchi A., Nishikawa S., Takai Y. J. Cell Biol. 146:1117-1132(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-320 (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE. Strain: C57BL/6.
[3]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 36-900 (ISOFORM 3). Tissue: Leukemia.
[4]	"Nectin-3: a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities." Satoh-Horikawa K., Nakanishi H., Takahashi K., Miyahara M., Nishimura M., Tachibana K., Mizoguchi A., Takai Y. J. Biol. Chem. 275:10291-10299(2000) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH PVRL3.
[5]	"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1107; SER-1182 AND SER-1275, MASS SPECTROMETRY. Tissue: Melanoma.
[6]	"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry." Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J. Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1107 AND SER-1182, MASS SPECTROMETRY. Tissue: Embryonic fibroblast.
[7]	"Solution structure of the FHA domain and RAS-binding domain in mouse AF-6 protein." RIKEN structural genomics initiative (RSGI) Submitted (JUL-2005) to the PDB data bank Cited for: STRUCTURE BY NMR OF 246-487.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AC155253 Genomic DNA. No translation available.
CAAA01106165 Genomic DNA. No translation available.
CAAA01134612 Genomic DNA. No translation available.
CAAA01201738 Genomic DNA. No translation available.
CAAA01218165 Genomic DNA. No translation available.
AF172447 mRNA. Translation: AAD54283.1.
AK016557 mRNA. No translation available.

IPI

IPI00845596.
IPI00853902.

RefSeq

NP_034936.1. NM_010806.1.

UniGene

Mm.59167.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1WLN	NMR	-	A	381-502	[»]
1WXA	NMR	-	A	246-348	[»]
3AXA	X-ray	2.78	A/B	1003-1095	[»]

ProteinModelPortal

Q9QZQ1.

SMR

Q9QZQ1. Positions 40-134, 249-348, 381-502, 759-910, 1001-1096, 1507-1685.

ModBase

Search...

PTM databases

PhosphoSite

Q9QZQ1.

Proteomic databases

PaxDb

Q9QZQ1.

PRIDE

Q9QZQ1.

Protocols and materials databases

DNASU

17356.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENSMUST00000139666; ENSMUSP00000118318; ENSMUSG00000068036.
ENSMUST00000150848; ENSMUSP00000122447; ENSMUSG00000068036.

GeneID

17356.

KEGG

mmu:17356.

UCSC

uc008amr.1. mouse.

Organism-specific databases

CTD

4301.

MGI

MGI:1314653. Mllt4.

Phylogenomic databases

eggNOG

NOG291597.

GeneTree

ENSGT00390000006525.

HOGENOM

HOG000008041.

HOVERGEN

HBG050463.

InParanoid

Q9QZQ1.

KO

K05702.

Gene expression databases

ArrayExpress

Q9QZQ1.

Bgee

Q9QZQ1.

Genevestigator

Q9QZQ1.

GermOnline

ENSMUSG00000068036. Mus musculus.

Family and domain databases

Gene3D

2.60.200.20. 1 hit.

InterPro

IPR018444. Dil_domain.
IPR002710. Dilute.
IPR000253. FHA_dom.
IPR001478. PDZ.
IPR000159. Ras-assoc.
IPR008984. SMAD_FHA_domain.
[Graphical view]

Pfam

PF01843. DIL. 1 hit.
PF00498. FHA. 1 hit.
PF00595. PDZ. 1 hit.
PF00788. RA. 2 hits.
[Graphical view]

SMART

SM00240. FHA. 1 hit.
SM00228. PDZ. 1 hit.
SM00314. RA. 2 hits.
[Graphical view]

SUPFAM

SSF50156. PDZ. 1 hit.
SSF49879. SMAD_FHA. 1 hit.

PROSITE

PS51126. DILUTE. 1 hit.
PS50006. FHA_DOMAIN. False negative.
PS50106. PDZ. 1 hit.
PS50200. RA. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

ChiTaRS

MLLT4. mouse.

EvolutionaryTrace

Q9QZQ1.

NextBio

291962.

SOURCE

Search...

Entry information

Entry name

AFAD_MOUSE

Accession

Primary (citable) accession number: Q9QZQ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 11, 2004
Last sequence update:	July 10, 2007
Last modified:	May 1, 2013
This is version 101 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families