Reviewed, UniProtKB/Swiss-Prot Q9QZB7 (ARP10_MOUSE)

Names and origin

Protein names

Recommended name:
    Actin-related protein 10

Gene names

Name:	Actr10
Synonyms:	Act11, Actr11, Arp11

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Cytoplasm › cytoskeleton By similarity.
Sequence similarities	Belongs to the actin family.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	microtubule-based movement Ref.1 Inferred from direct assay. Source: MGI
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW dynactin complex Ref.1 Inferred from direct assay. Source: MGI
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
ACTR1B	P42025	1	EBI-367600,EBI-367493	From a different organism.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 417	417	Actin-related protein 10		PRO_0000089132
Amino acid modifications
	Modified residue	414	1	Phosphoserine Ref.3
Experimental info
	Sequence conflict	9	1	T → S in AAH02227. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q9QZB7-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: 14016D909310E581	FASTA	417	46,222
	10 20 30 40 50 60 MPLYEGLGTG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMSK PIKVVQYNIN 70 80 90 100 110 120 TEELYSYLKE FIHILYFRHL LVNPRDRRVV VIESVLCPSH FRETLTRVLF KYFEVPSVLL 130 140 150 160 170 180 APSHLMALLT LGINSAMVLD CGYRESLVLP IYEGIPILNC WGALPLGGKA LHKELETQLL 190 200 210 220 230 240 EQCTVDTGAA KGQSLPSVMG SVPEGVLEDI KVRTCFVSDL KRGLQIQAAK FNIDGNNERP 250 260 270 280 290 300 TPPPNVDYPL DGEKILHVLG SIRDSVVEIL FEQDNEEKSV ATLILDSLLQ CPIDTRKQLA 310 320 330 340 350 360 ENLVIIGGTS MLPGFLHRLL AEIRYLVEKP KYKKTLGTKN FRIHTPPAKA NCVAWLGGAV 370 380 390 400 410 FGALQDILGS RSISKEYYNQ TGRIPDWCSL NNPPLEMMFD VGKAQPPLMK RAFSTEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 minifilament pointed end." Eckley D.M., Gill S.R., Melkonian K.A., Bingham J.B., Goodson H.V., Heuser J.E., Schroer T.A. J. Cell Biol. 147:307-320(1999) [PubMed: 10525537] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]	"Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry." Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M. J. Proteome Res. 7:5314-5326(2008) [PubMed: 18973353] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-414, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF190797 mRNA. Translation: AAF05617.1. BC002227 mRNA. Translation: AAH02227.1.
IPI	IPI00137206.
RefSeq	NP_062759.2.
UniGene	Mm.29317
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9QZB7. 2 interactions.
STRING	Q9QZB7.
PTM databases
PhosphoSite	Q9QZB7.
Proteomic databases
PRIDE	Q9QZB7.
Genome annotation databases
Ensembl	ENSMUST00000021479; ENSMUSP00000021479; ENSMUSG00000021076; Mus musculus. [Genome view]
GeneID	56444.
KEGG	mmu:56444.
UCSC	uc007nty.1. mouse.
Organism-specific databases
CTD	56444.
MGI	MGI:1891654. Actr10.
Phylogenomic databases
HOGENOM	HBG713850.
HOVERGEN	Q9QZB7.
InParanoid	Q9QZB7.
Gene expression databases
ArrayExpress	Q9QZB7.
Bgee	Q9QZB7.
CleanEx	MM_ACTR10.
Genevestigator	Q9QZB7.
GermOnline	ENSMUSG00000021076. Mus musculus.
Family and domain databases
InterPro	IPR004000. Actin-like. [Graphical view]
PANTHER	PTHR11937. Actin_like. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	312646.
SOURCE	Search...

Entry information

Entry name

ARP10_MOUSE

Accession

Primary (citable) accession number: Q9QZB7
Secondary accession number(s): Q99LU1

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 2000
Last modified:	December 15, 2009
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)