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Protein

Actin-related protein 10

Gene

Actr10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • microtubule-based movement Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 10
Alternative name(s):
Actin-related protein 11
Gene namesi
Name:Actr10
Synonyms:Act11, Actr11, Arp11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1891654. Actr10.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB-KW
  • dynactin complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 417417Actin-related protein 10PRO_0000089132Add
BLAST

Proteomic databases

EPDiQ9QZB7.
MaxQBiQ9QZB7.
PaxDbiQ9QZB7.
PRIDEiQ9QZB7.

PTM databases

iPTMnetiQ9QZB7.
PhosphoSiteiQ9QZB7.

Expressioni

Gene expression databases

BgeeiQ9QZB7.
CleanExiMM_ACTR10.
GenevisibleiQ9QZB7. MM.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ACTR1BP420252EBI-367600,EBI-367493From a different organism.

Protein-protein interaction databases

BioGridi207985. 2 interactions.
IntActiQ9QZB7. 2 interactions.
STRINGi10090.ENSMUSP00000021479.

Structurei

3D structure databases

ProteinModelPortaliQ9QZB7.
SMRiQ9QZB7. Positions 12-390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
GeneTreeiENSGT00840000129933.
HOGENOMiHOG000034069.
HOVERGENiHBG050578.
InParanoidiQ9QZB7.
KOiK16576.
OMAiKPIKVVQ.
OrthoDBiEOG7DZ8M2.
TreeFamiTF315151.

Family and domain databases

InterProiIPR004000. Actin.
IPR027127. Arp10.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF14. PTHR11937:SF14. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QZB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLYEGLGSG GEKTAVVIDL GEAFTKCGFA GETGPRCIIP SVIKRAGMSK
60 70 80 90 100
PIKVVQYNIN TEELYSYLKE FIHILYFRHL LVNPRDRRVV VIESVLCPSH
110 120 130 140 150
FRETLTRVLF KYFEVPSVLL APSHLMALLT LGINSAMVLD CGYRESLVLP
160 170 180 190 200
IYEGIPILNC WGALPLGGKA LHKELETQLL EQCTVDTGAA KGQSLPSVMG
210 220 230 240 250
SVPEGVLEDI KVRTCFVSDL KRGLQIQAAK FNIDGNNERP TPPPNVDYPL
260 270 280 290 300
DGEKILHVLG SIRDSVVEIL FEQDNEEKSV ATLILDSLLQ CPIDTRKQLA
310 320 330 340 350
ENLVIIGGTS MLPGFLHRLL AEIRYLVEKP KYKKTLGTKN FRIHTPPAKA
360 370 380 390 400
NCVAWLGGAV FGALQDILGS RSISKEYYNQ TGRIPDWCSL NNPPLEMMFD
410
VGKAQPPLMK RAFSTEK
Length:417
Mass (Da):46,208
Last modified:July 27, 2011 - v2
Checksum:iDFA8D7CFF0C64B0D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91S → T in AAF05617 (PubMed:10525537).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190797 mRNA. Translation: AAF05617.1.
AK161642 mRNA. Translation: BAE36507.1.
BC002227 mRNA. Translation: AAH02227.1.
CCDSiCCDS25960.1.
RefSeqiNP_062759.2. NM_019785.2.
UniGeneiMm.29317.

Genome annotation databases

EnsembliENSMUST00000021479; ENSMUSP00000021479; ENSMUSG00000021076.
GeneIDi56444.
KEGGimmu:56444.
UCSCiuc007nty.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF190797 mRNA. Translation: AAF05617.1.
AK161642 mRNA. Translation: BAE36507.1.
BC002227 mRNA. Translation: AAH02227.1.
CCDSiCCDS25960.1.
RefSeqiNP_062759.2. NM_019785.2.
UniGeneiMm.29317.

3D structure databases

ProteinModelPortaliQ9QZB7.
SMRiQ9QZB7. Positions 12-390.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi207985. 2 interactions.
IntActiQ9QZB7. 2 interactions.
STRINGi10090.ENSMUSP00000021479.

PTM databases

iPTMnetiQ9QZB7.
PhosphoSiteiQ9QZB7.

Proteomic databases

EPDiQ9QZB7.
MaxQBiQ9QZB7.
PaxDbiQ9QZB7.
PRIDEiQ9QZB7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021479; ENSMUSP00000021479; ENSMUSG00000021076.
GeneIDi56444.
KEGGimmu:56444.
UCSCiuc007nty.2. mouse.

Organism-specific databases

CTDi55860.
MGIiMGI:1891654. Actr10.

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
GeneTreeiENSGT00840000129933.
HOGENOMiHOG000034069.
HOVERGENiHBG050578.
InParanoidiQ9QZB7.
KOiK16576.
OMAiKPIKVVQ.
OrthoDBiEOG7DZ8M2.
TreeFamiTF315151.

Miscellaneous databases

ChiTaRSiActr10. mouse.
PROiQ9QZB7.
SOURCEiSearch...

Gene expression databases

BgeeiQ9QZB7.
CleanExiMM_ACTR10.
GenevisibleiQ9QZB7. MM.

Family and domain databases

InterProiIPR004000. Actin.
IPR027127. Arp10.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PTHR11937:SF14. PTHR11937:SF14. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 minifilament pointed end."
    Eckley D.M., Gill S.R., Melkonian K.A., Bingham J.B., Goodson H.V., Heuser J.E., Schroer T.A.
    J. Cell Biol. 147:307-320(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Heart, Kidney, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiARP10_MOUSE
AccessioniPrimary (citable) accession number: Q9QZB7
Secondary accession number(s): Q3TT18, Q99LU1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: July 27, 2011
Last modified: June 8, 2016
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.