Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Myoglobin

Gene

Mb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi65 – 651Iron (heme distal ligand)
Metal bindingi94 – 941Iron (heme proximal ligand)

GO - Molecular functioni

  • heme binding Source: RGD
  • metal ion binding Source: UniProtKB-KW
  • oxygen binding Source: RGD
  • oxygen transporter activity Source: UniProtKB-KW

GO - Biological processi

  • brown fat cell differentiation Source: Ensembl
  • enucleate erythrocyte differentiation Source: Ensembl
  • heart development Source: Ensembl
  • oxygen transport Source: RGD
  • response to hormone Source: RGD
  • response to hydrogen peroxide Source: RGD
  • response to hypoxia Source: Ensembl
  • slow-twitch skeletal muscle fiber contraction Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:Mb
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi620411. Mb.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 154153MyoglobinPRO_0000053341Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei4 – 41PhosphoserineCombined sources
Modified residuei32 – 321PhosphoserineCombined sources
Modified residuei68 – 681PhosphothreonineBy similarity
Modified residuei121 – 1211PhosphoserineCombined sources
Modified residuei133 – 1331PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9QZ76.
PRIDEiQ9QZ76.

PTM databases

iPTMnetiQ9QZ76.
PhosphoSiteiQ9QZ76.

Expressioni

Gene expression databases

BgeeiENSRNOG00000004583.
GenevisibleiQ9QZ76. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006184.

Structurei

3D structure databases

ProteinModelPortaliQ9QZ76.
SMRiQ9QZ76. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiQ9QZ76.
OMAiKKKGQHE.
OrthoDBiEOG091G0OAO.
PhylomeDBiQ9QZ76.
TreeFamiTF332967.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9QZ76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDGEWQM VLNIWGKVEG DLAGHGQEVL ISLFKAHPET LEKFDKFKNL
60 70 80 90 100
KSEEEMKSSE DLKKHGCTVL TALGTILKKK GQHAAEIQPL AQSHATKHKI
110 120 130 140 150
PVKYLEFISE VIIQVLKKRY SGDFGADAQG AMSKALELFR NDIAAKYKEL

GFQG
Length:154
Mass (Da):17,157
Last modified:January 23, 2007 - v3
Checksum:i98B31BE57FA020DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF197916 mRNA. Translation: AAF05848.1.
BC070511 mRNA. Translation: AAH70511.1.
RefSeqiNP_067599.1. NM_021588.2.
UniGeneiRn.40511.

Genome annotation databases

EnsembliENSRNOT00000006184; ENSRNOP00000006184; ENSRNOG00000004583.
GeneIDi59108.
KEGGirno:59108.
UCSCiRGD:620411. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF197916 mRNA. Translation: AAF05848.1.
BC070511 mRNA. Translation: AAH70511.1.
RefSeqiNP_067599.1. NM_021588.2.
UniGeneiRn.40511.

3D structure databases

ProteinModelPortaliQ9QZ76.
SMRiQ9QZ76. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006184.

PTM databases

iPTMnetiQ9QZ76.
PhosphoSiteiQ9QZ76.

Proteomic databases

PaxDbiQ9QZ76.
PRIDEiQ9QZ76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000006184; ENSRNOP00000006184; ENSRNOG00000004583.
GeneIDi59108.
KEGGirno:59108.
UCSCiRGD:620411. rat.

Organism-specific databases

CTDi4151.
RGDi620411. Mb.

Phylogenomic databases

eggNOGiKOG3378. Eukaryota.
COG1018. LUCA.
GeneTreeiENSGT00730000110844.
HOGENOMiHOG000070111.
HOVERGENiHBG107340.
InParanoidiQ9QZ76.
OMAiKKKGQHE.
OrthoDBiEOG091G0OAO.
PhylomeDBiQ9QZ76.
TreeFamiTF332967.

Miscellaneous databases

PROiQ9QZ76.

Gene expression databases

BgeeiENSRNOG00000004583.
GenevisibleiQ9QZ76. RN.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMYG_RAT
AccessioniPrimary (citable) accession number: Q9QZ76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 105 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.