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Protein

Heat shock protein beta-3

Gene

Hspb3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Inhibitor of actin polymerization.By similarity

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein beta-3
Short name:
HspB3
Gene namesi
Name:Hspb3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi68345. Hspb3.

Subcellular locationi

  • Cytoplasm By similarity
  • Nucleus By similarity

  • Note: Translocates to nuclear foci during heat shock.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 152152Heat shock protein beta-3PRO_0000125938Add
BLAST

Proteomic databases

PaxDbiQ9QZ58.
PRIDEiQ9QZ58.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014627.

Structurei

3D structure databases

ProteinModelPortaliQ9QZ58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3591. Eukaryota.
ENOG410YERS. LUCA.
HOGENOMiHOG000286024.
HOVERGENiHBG052039.
InParanoidiQ9QZ58.
KOiK09544.
PhylomeDBiQ9QZ58.

Family and domain databases

InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QZ58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKIILRHLI ETPVRYQEEF EARGLEDCRL DHALYALPGP TIEDLRKARG
60 70 80 90 100
TPKALAEDSD SAETPPGEGK SRFQILLDVV QFLPEDIIIQ TFEGWLLIKA
110 120 130 140 150
QHGTRMDEHG FISRSFTRQY KLPDGVETKD LSAILCHDGI LVVEVKDPLE

TK
Length:152
Mass (Da):17,210
Last modified:May 1, 2000 - v1
Checksum:iDAC532E8A00484E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF203374 mRNA. Translation: AAF09588.1.
RefSeqiNP_113938.1. NM_031750.1.
UniGeneiRn.20155.

Genome annotation databases

GeneIDi78951.
KEGGirno:78951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF203374 mRNA. Translation: AAF09588.1.
RefSeqiNP_113938.1. NM_031750.1.
UniGeneiRn.20155.

3D structure databases

ProteinModelPortaliQ9QZ58.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000014627.

Proteomic databases

PaxDbiQ9QZ58.
PRIDEiQ9QZ58.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi78951.
KEGGirno:78951.

Organism-specific databases

CTDi8988.
RGDi68345. Hspb3.

Phylogenomic databases

eggNOGiKOG3591. Eukaryota.
ENOG410YERS. LUCA.
HOGENOMiHOG000286024.
HOVERGENiHBG052039.
InParanoidiQ9QZ58.
KOiK09544.
PhylomeDBiQ9QZ58.

Miscellaneous databases

PROiQ9QZ58.

Family and domain databases

InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of a rat small heat shock protein B3 (HSPB3)."
    Tam W.H., Chan K.K., Tsui S.K.W., Fung K.P., Lee C.Y., Waye M.M.Y.
    Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Sprague-Dawley.

Entry informationi

Entry nameiHSPB3_RAT
AccessioniPrimary (citable) accession number: Q9QZ58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: May 1, 2000
Last modified: June 8, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.