Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Epithelial membrane protein 3

Gene

Emp3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probably involved in cell proliferation and cell-cell interactions.

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Epithelial membrane protein 3
Short name:
EMP-3
Gene namesi
Name:Emp3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi621094. Emp3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei139 – 159HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001646621 – 163Epithelial membrane protein 3Add BLAST163

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi46N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi56N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9QYW5.
PRIDEiQ9QYW5.

Expressioni

Gene expression databases

BgeeiENSRNOG00000021104.
GenevisibleiQ9QYW5. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000028656.

Family & Domainsi

Sequence similaritiesi

Belongs to the PMP-22/EMP/MP20 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IY40. Eukaryota.
ENOG4111MF9. LUCA.
GeneTreeiENSGT00510000046328.
HOGENOMiHOG000059542.
HOVERGENiHBG001690.
InParanoidiQ9QYW5.
OMAiSDLWYNC.
OrthoDBiEOG091G0RF4.
PhylomeDBiQ9QYW5.
TreeFamiTF330414.

Family and domain databases

InterProiView protein in InterPro
IPR003934. EMP_3.
IPR004031. PMP22/EMP/MP20/Claudin.
IPR004032. PMP22_EMP_MP20.
PANTHERiPTHR10671:SF68. PTHR10671:SF68. 1 hit.
PfamiView protein in Pfam
PF00822. PMP22_Claudin. 1 hit.
PRINTSiPR01453. EPMEMFAMILY.
PR01456. EPMEMPROT3.
PROSITEiView protein in PROSITE
PS01221. PMP22_1. 1 hit.
PS01222. PMP22_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9QYW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLLLVVSA LHILILVLLF VATLDKSWWT LPEKESLNLW YDCTWNTTAK
60 70 80 90 100
TWACSNVSEN GWLKAVQALM VLSLILCCLS FILFMIQLYT MRRGGLFYAT
110 120 130 140 150
GLCQLCTSAA VFSGALIYAI HAKEILAKHP SGGSFGYCFA LAWVAFPLAL
160
VSGIIYIHLR KRE
Length:163
Mass (Da):18,198
Last modified:May 1, 2000 - v1
Checksum:i8B395380D0C92558
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10889 mRNA. Translation: CAB61834.1.
BC088131 mRNA. Translation: AAH88131.1.
RefSeqiNP_110474.1. NM_030847.1.
XP_006229220.1. XM_006229158.3.
XP_008757640.1. XM_008759418.1.
UniGeneiRn.6782.

Genome annotation databases

EnsembliENSRNOT00000028656; ENSRNOP00000028656; ENSRNOG00000021104.
GeneIDi81505.
KEGGirno:81505.
UCSCiRGD:621094. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiEMP3_RAT
AccessioniPrimary (citable) accession number: Q9QYW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: May 1, 2000
Last modified: May 10, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families