Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

C3G protein

Gene

Rapgef1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-170968. Frs2-mediated activation.

Names & Taxonomyi

Protein namesi
Submitted name:
C3G proteinImported
Gene namesi
Name:Rapgef1Imported
Synonyms:c3gImported, Grf2Imported, Grf2_v1Imported, Grf2_v2Imported, Rapgef1_v1Imported, Rapgef1_v2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi619793. Rapgef1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9QYV3.

PTM databases

iPTMnetiQ9QYV3.
PhosphoSiteiQ9QYV3.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057696.

Structurei

3D structure databases

ProteinModelPortaliQ9QYV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini623 – 745123N-terminal Ras-GEFInterPro annotationAdd
BLAST
Domaini775 – 1000226Ras-GEFInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains N-terminal Ras-GEF domain.SAAS annotation
Contains Ras-GEF domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG3417. Eukaryota.
ENOG410XP7D. LUCA.
HOVERGENiHBG058477.
PhylomeDBiQ9QYV3.

Family and domain databases

CDDicd06224. REM. 1 hit.
Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
PROSITEiPS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9QYV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FKTIVDKMAI DKKVLEMLPG SASKVLEAIL PLVQTDPRIQ HSSALSSCYS
60 70 80 90 100
RVYQSLANLI RWSDQVMLEG VNSEDKEMVT TVKGVIKAVL DGVKELVRIT
110 120 130 140 150
IEKQGRPSPT SPVKPSSPAS KPDGQPELPL TEREMEILNK TSVSPSTELL
160 170 180 190 200
PDSTSEEVAP PKPPLPGIRV VDNSPPALPP KKRQSAPSPT RVAVVAPMSR
210 220 230 240 250
AVSGSSLPVG INRQDFDVEC YTQRRLSGGS RSCGGESPRL SPCSSTGKLS
260 270 280 290 300
RSDEQLSSLD RDSGQCSRNT SCETLDHYDP DYEFLQQDLS NADQTPPQAA
310 320 330 340 350
CNLSPLPESM GESGPPFVGY SFQLPLGSCL QQDGQQTDTP PALPEKKRRS
360 370 380 390 400
AVSQTTDSSG CRVSYERHPS QYDNISEDDL QNPAQPVSYP PFAAILPFQQ
410 420 430 440 450
GASSTPVEFV GDFSVPESAG DPEKPPPLPE KKNKHMLAYM QLLEDYSEPQ
460 470 480 490 500
PSMFYQTPQS EHIYQQKNKM LMEVYGFSDS FCGSDSTQEL APPPALPPKQ
510 520 530 540 550
RQLASYAASS FSVSHCVQQT KVAFTPEDGS AAQGLSVSVS NSFLNRHGSL
560 570 580 590 600
PVPSEPPSGK DGHPRDLSVS SASGKDSREN GERSPKSLDA LESAQSEEEV
610 620 630 640 650
DELSLIDHNE IMARLTLKQE GDDGPDVRGG SGDILLVHAT ETDRKDLVLY
660 670 680 690 700
CEAFLTTYRT FISPEELIKK LQCRYEKFSP FADTFKKRVS KNTFFVLVRV
710 720 730 740 750
VDELCLVELT EEILKLLMEL VFRLVCSGEL SLARVLRKNI LDKVDQKKLL
760 770 780 790 800
RCAHSDQPLA ARGVAARPGT LHDFHSHEIA EQLTLLDAEL FYKIEIPEVL
810 820 830 840 850
LWAKEQNEEL KSPNLTQFTE HFNNMSYWVR SIIMLQEKAQ DRERLLLKFI
860 870 880 890 900
KIMKHLRKLN NFNSYLAILS ALDSAPIRRL EWQRQTSEGL AEYCTLIDSS
910 920 930 940 950
SSFRAYRAAL SEVEPPCIPY LGLILQDLTF VHLGNPDYID GKVNFSKRWQ
960 970 980 990 1000
QFNILDSMRC FQQVHYEIRR NDDIINFFND FSDHLAEEAL WELSLKIKPR
1010
NITRRKTDRE EKT
Length:1,013
Mass (Da):113,178
Last modified:May 1, 2000 - v1
Checksum:i6336066FCD338E06
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ249986 mRNA. Translation: CAB59566.1.
UniGeneiRn.85879.

Genome annotation databases

UCSCiRGD:619793. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ249986 mRNA. Translation: CAB59566.1.
UniGeneiRn.85879.

3D structure databases

ProteinModelPortaliQ9QYV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000057696.

PTM databases

iPTMnetiQ9QYV3.
PhosphoSiteiQ9QYV3.

Proteomic databases

PaxDbiQ9QYV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:619793. rat.

Organism-specific databases

RGDi619793. Rapgef1.

Phylogenomic databases

eggNOGiKOG3417. Eukaryota.
ENOG410XP7D. LUCA.
HOVERGENiHBG058477.
PhylomeDBiQ9QYV3.

Enzyme and pathway databases

ReactomeiR-RNO-170968. Frs2-mediated activation.

Family and domain databases

CDDicd06224. REM. 1 hit.
Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
[Graphical view]
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
PROSITEiPS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9QYV3_RAT
AccessioniPrimary (citable) accession number: Q9QYV3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.