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Protein
Submitted name:

C3G protein

Gene

Rapgef1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
C3G proteinImported
Gene namesi
Name:Rapgef1Imported
Synonyms:c3gImported, Grf2Imported, Grf2_v1Imported, Grf2_v2Imported, Rapgef1_v1Imported, Rapgef1_v2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi619793. Rapgef1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ9QYV3.

PTM databases

iPTMnetiQ9QYV3.
PhosphoSitePlusiQ9QYV3.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ9QYV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini623 – 745N-terminal Ras-GEFInterPro annotationAdd BLAST123
Domaini775 – 1000Ras-GEFInterPro annotationAdd BLAST226

Phylogenomic databases

eggNOGiKOG3417. Eukaryota.
ENOG410XP7D. LUCA.
HOVERGENiHBG058477.
PhylomeDBiQ9QYV3.

Family and domain databases

CDDicd00155. RasGEF. 1 hit.
cd06224. REM. 1 hit.
Gene3Di1.10.840.10. 1 hit.
InterProiView protein in InterPro
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom_sf.
IPR001895. RASGEF_cat_dom.
IPR036964. RASGEF_cat_dom_sf.
PfamiView protein in Pfam
PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
SMARTiView protein in SMART
SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SUPFAMiSSF48366. SSF48366. 1 hit.
PROSITEiView protein in PROSITE
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9QYV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FKTIVDKMAI DKKVLEMLPG SASKVLEAIL PLVQTDPRIQ HSSALSSCYS
60 70 80 90 100
RVYQSLANLI RWSDQVMLEG VNSEDKEMVT TVKGVIKAVL DGVKELVRIT
110 120 130 140 150
IEKQGRPSPT SPVKPSSPAS KPDGQPELPL TEREMEILNK TSVSPSTELL
160 170 180 190 200
PDSTSEEVAP PKPPLPGIRV VDNSPPALPP KKRQSAPSPT RVAVVAPMSR
210 220 230 240 250
AVSGSSLPVG INRQDFDVEC YTQRRLSGGS RSCGGESPRL SPCSSTGKLS
260 270 280 290 300
RSDEQLSSLD RDSGQCSRNT SCETLDHYDP DYEFLQQDLS NADQTPPQAA
310 320 330 340 350
CNLSPLPESM GESGPPFVGY SFQLPLGSCL QQDGQQTDTP PALPEKKRRS
360 370 380 390 400
AVSQTTDSSG CRVSYERHPS QYDNISEDDL QNPAQPVSYP PFAAILPFQQ
410 420 430 440 450
GASSTPVEFV GDFSVPESAG DPEKPPPLPE KKNKHMLAYM QLLEDYSEPQ
460 470 480 490 500
PSMFYQTPQS EHIYQQKNKM LMEVYGFSDS FCGSDSTQEL APPPALPPKQ
510 520 530 540 550
RQLASYAASS FSVSHCVQQT KVAFTPEDGS AAQGLSVSVS NSFLNRHGSL
560 570 580 590 600
PVPSEPPSGK DGHPRDLSVS SASGKDSREN GERSPKSLDA LESAQSEEEV
610 620 630 640 650
DELSLIDHNE IMARLTLKQE GDDGPDVRGG SGDILLVHAT ETDRKDLVLY
660 670 680 690 700
CEAFLTTYRT FISPEELIKK LQCRYEKFSP FADTFKKRVS KNTFFVLVRV
710 720 730 740 750
VDELCLVELT EEILKLLMEL VFRLVCSGEL SLARVLRKNI LDKVDQKKLL
760 770 780 790 800
RCAHSDQPLA ARGVAARPGT LHDFHSHEIA EQLTLLDAEL FYKIEIPEVL
810 820 830 840 850
LWAKEQNEEL KSPNLTQFTE HFNNMSYWVR SIIMLQEKAQ DRERLLLKFI
860 870 880 890 900
KIMKHLRKLN NFNSYLAILS ALDSAPIRRL EWQRQTSEGL AEYCTLIDSS
910 920 930 940 950
SSFRAYRAAL SEVEPPCIPY LGLILQDLTF VHLGNPDYID GKVNFSKRWQ
960 970 980 990 1000
QFNILDSMRC FQQVHYEIRR NDDIINFFND FSDHLAEEAL WELSLKIKPR
1010
NITRRKTDRE EKT
Length:1,013
Mass (Da):113,178
Last modified:May 1, 2000 - v1
Checksum:i6336066FCD338E06
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ249986 mRNA. Translation: CAB59566.1.
UniGeneiRn.85879.

Genome annotation databases

UCSCiRGD:619793. rat.

Similar proteinsi

Entry informationi

Entry nameiQ9QYV3_RAT
AccessioniPrimary (citable) accession number: Q9QYV3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: November 22, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)