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Q9QYE3

- BC11A_MOUSE

UniProt

Q9QYE3 - BC11A_MOUSE

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Protein

B-cell lymphoma/leukemia 11A

Gene
Bcl11a, Ctip1, Evi9, Kiaa1809
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri170 – 19324C2H2-type 1Add
BLAST
Zinc fingeri377 – 39923C2H2-type 2Add
BLAST
Zinc fingeri405 – 42925C2H2-type 3Add
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro
  3. protein binding Source: UniProtKB
  4. transcription corepressor activity Source: MGI

GO - Biological processi

  1. B cell differentiation Source: MGI
  2. negative regulation of gene expression Source: MGI
  3. protein sumoylation Source: UniProtKB
  4. regulation of transcription, DNA-templated Source: UniProtKB-KW
  5. T cell differentiation Source: MGI
  6. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
B-cell lymphoma/leukemia 11A
Short name:
BCL-11A
Alternative name(s):
B-cell CLL/lymphoma 11A
COUP-TF-interacting protein 1
Ecotropic viral integration site 9 protein
Short name:
EVI-9
Gene namesi
Name:Bcl11a
Synonyms:Ctip1, Evi9, Kiaa1809
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:106190. Bcl11a.

Subcellular locationi

Cytoplasm. Nucleus
Note: Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nuclear body Source: UniProtKB
  3. nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi123 – 1231K → R: No effect on sumoylation. 1 Publication
Mutagenesisi637 – 6371K → R: Abolishes sumoylation. No effect on nuclear body location. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 773773B-cell lymphoma/leukemia 11APRO_0000047103Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei205 – 2051Phosphoserine By similarity
Modified residuei332 – 3321Phosphoserine By similarity
Modified residuei608 – 6081Phosphoserine By similarity
Modified residuei625 – 6251Phosphoserine By similarity
Modified residuei630 – 6301Phosphoserine By similarity
Cross-linki634 – 634Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO-1)1 Publication
Modified residuei701 – 7011Phosphothreonine By similarity

Post-translational modificationi

Sumoylated with SUMO1.1 Publication

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiQ9QYE3.
PaxDbiQ9QYE3.
PRIDEiQ9QYE3.

PTM databases

PhosphoSiteiQ9QYE3.

Expressioni

Tissue specificityi

Isoforms are expressed in a tissue-specific fashion. Isoforms 1, isoform 2, and isoform 3 are expressed at similar levels in testis, kidney and spleen. Isoform 1 is expressed in the stomach, and isoform 2 is expressed exclusively in the lung. Overexpression following proviral integration in hematopoietic cells results in the generation of myeloid leukemia.

Developmental stagei

Highly expressed in the developing embryo.

Gene expression databases

ArrayExpressiQ9QYE3.
BgeeiQ9QYE3.
CleanExiMM_BCL11A.
GenevestigatoriQ9QYE3.

Interactioni

Subunit structurei

Interacts with TFCOUP1, PIAS3, ARP1 and EAR2.2 Publications

Protein-protein interaction databases

BioGridi199546. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9QYE3.
SMRiQ9QYE3. Positions 45-74, 165-202, 379-457.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 210210Required for nuclear body formation and for SUMO1 recruitmentAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi260 – 373114Pro-richAdd
BLAST
Compositional biasi481 – 50929Glu-richAdd
BLAST

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri170 – 19324C2H2-type 1Add
BLAST
Zinc fingeri377 – 39923C2H2-type 2Add
BLAST
Zinc fingeri405 – 42925C2H2-type 3Add
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG271772.
GeneTreeiENSGT00530000063542.
HOVERGENiHBG050673.
OMAiFRMEAQE.
OrthoDBiEOG7MH0XP.
PhylomeDBiQ9QYE3.
TreeFamiTF318131.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequences (8)i

Sequence statusi: Complete.

This entry describes 8 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9QYE3-1) [UniParc]FASTAAdd to Basket

Also known as: a

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ    50
CQMNFPLGDI LIFIEHKRKQ CNGSLCLEKG VDKPPSPSPI EMKKASNPVE 100
VGIQVTPEDD DCLSTSSRGI CPKQEHIADK LLHWRGLSSP RSAHGALIPT 150
PGMSAEYAPQ GICKDEPSSY TCTTCKQPFT SAWFLLQHAQ NTHGLRIYLE 200
SEHGSPLTPR VGIPSGLGAE CPSQPPLHGI HIADNNPFNL LRIPGSVSRE 250
ASGLAEGRFP PTPPLFSPPP RHHLDPHRIE RLGAEEMALA THHPSAFDRV 300
LRLNPMAMEP PAMDFSRRLR ELAGNTSSPP LSPGRPSPMQ RLLQPFQPGS 350
KPPFLATPPL PPLQSAPPPS QPPVKSKSCE FCGKTFKFQS NLVVHRRSHT 400
GEKPYKCNLC DHACTQASKL KRHMKTHMHK SSPMTVKSDD GLSTASSPEP 450
GTSDLVGSAS SALKSVVAKF KSENDPNLIP ENGDEEEEED DEEEEEEEEE 500
EEEELTESER VDYGFGLSLE AARHHENSSR GAVVGVGDEG RALPDVMQGM 550
VLSSMQHFSE AFHQVLGEKH KRSHLAEAEG HRDTCDEDSV AGESDRIDDG 600
TVNGRGCSPG ESASGGLSKK LLLGSPSSLS PFSKRIKLEK EFDLPPAAMP 650
NTENVYSQWL AGYAASRQLK DPFLTFGDSR QSPFASSSEH SSENGSLRFS 700
TPPGELDGGI SGRSGTGSGG STPHISGPGP GRPSSKEGRR SDTCPSHTPV 750
RRSTPRAQDV WQFSDGSSRT LKF 773
Length:773
Mass (Da):83,855
Last modified:May 1, 2000 - v1
Checksum:i3BD10B7F14AA9EC4
GO
Isoform 2 (identifier: Q9QYE3-10) [UniParc]FASTAAdd to Basket

Also known as: b

The sequence of this isoform differs from the canonical sequence as follows:
     1-286: Missing.
     726-773: Missing.

Show »
Length:439
Mass (Da):47,399
Checksum:i120BF060E661E99B
GO
Isoform 3 (identifier: Q9QYE3-11) [UniParc]FASTAAdd to Basket

Also known as: c

The sequence of this isoform differs from the canonical sequence as follows:
     212-744: Missing.

Show »
Length:240
Mass (Da):26,553
Checksum:i569B5B4CC3C20E2E
GO
Isoform 4 (identifier: Q9QYE3-12) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-423: Missing.
     745-773: PSHTPVRRSTPRAQDVWQFSDGSSRTLKF → EYCGKVFKNC...RVLNNDIKTE

Show »
Length:412
Mass (Da):44,826
Checksum:i1A2AFD70252887C1
GO
Isoform 5 (identifier: Q9QYE3-13) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     212-243: GIPSGLGAECPSQPPLHGIHIADNNPFNLLRI → LHTPPFGVVPRELKMCGSFRMEAQEPLSSEKL
     244-773: Missing.

Show »
Length:243
Mass (Da):26,824
Checksum:iB19C19FD90473679
GO
Isoform 6 (identifier: Q9QYE3-14) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-52: Missing.
     212-243: GIPSGLGAECPSQPPLHGIHIADNNPFNLLRI → LHTPPFGVVPRELKMCGSFRMEAQEPLSSEKL
     244-773: Missing.

Show »
Length:191
Mass (Da):21,075
Checksum:i23B17797A92CF20B
GO
Isoform 7 (identifier: Q9QYE3-15) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     131-773: Missing.

Show »
Length:130
Mass (Da):14,310
Checksum:iE9335B3326D95236
GO
Isoform 8 (identifier: Q9QYE3-16) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-286: Missing.

Show »
Length:487
Mass (Da):52,639
Checksum:iC96493A37D33CDC0
GO

Sequence cautioni

The sequence AAF63682.1 differs from that shown. Reason: Frameshift at position 744.
The sequence BAC65839.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 423423Missing in isoform 4. VSP_009556Add
BLAST
Alternative sequencei1 – 286286Missing in isoform 2 and isoform 8. VSP_009557Add
BLAST
Alternative sequencei1 – 5252Missing in isoform 6. VSP_009558Add
BLAST
Alternative sequencei131 – 773643Missing in isoform 7. VSP_009559Add
BLAST
Alternative sequencei212 – 744533Missing in isoform 3. VSP_009560Add
BLAST
Alternative sequencei212 – 24332GIPSG…NLLRI → LHTPPFGVVPRELKMCGSFR MEAQEPLSSEKL in isoform 5 and isoform 6. VSP_009561Add
BLAST
Alternative sequencei244 – 773530Missing in isoform 5 and isoform 6. VSP_009562Add
BLAST
Alternative sequencei726 – 77348Missing in isoform 2. VSP_009563Add
BLAST
Alternative sequencei745 – 77329PSHTP…RTLKF → EYCGKVFKNCSNLTVHRRSH TGERPYKCELCNYACAQSSK LTRHMKTHGQVGKDVYKCEI CKMPFSVYSTLEKHMKKWHS DRVLNNDIKTE in isoform 4. VSP_009564Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti104 – 1041Q → K in BAB23285. 1 Publication
Sequence conflicti129 – 1291D → G in BAC65839. 1 Publication
Sequence conflicti211 – 2111V → G in AAF65929. 1 Publication
Sequence conflicti673 – 6731F → L in AAF63682. 1 Publication
Sequence conflicti699 – 6991F → L in AAF65928. 1 Publication
Sequence conflicti743 – 7431T → I in AAF63682. 1 Publication
Sequence conflicti773 – 7731F → L in AAF63682. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF051525 mRNA. Translation: AAF22430.1.
AF169036 mRNA. Translation: AAF65928.1.
AF169037 mRNA. Translation: AAF65929.1.
AF186018 mRNA. Translation: AAF63682.1. Frameshift.
AK004395 mRNA. Translation: BAB23285.1.
AK043677 mRNA. Translation: BAC31616.1.
AK045556 mRNA. Translation: BAC32416.1.
AK049700 mRNA. Translation: BAC33881.1.
AK122557 mRNA. Translation: BAC65839.1. Different initiation.
BC010585 mRNA. Translation: AAH10585.1.
BC051418 mRNA. Translation: AAH51418.1.
CCDSiCCDS24483.1. [Q9QYE3-1]
CCDS48758.1. [Q9QYE3-13]
CCDS48759.1. [Q9QYE3-14]
PIRiPT0706.
RefSeqiNP_001152761.1. NM_001159289.1.
NP_001152762.1. NM_001159290.1. [Q9QYE3-14]
NP_001229863.1. NM_001242934.1.
NP_057916.1. NM_016707.3. [Q9QYE3-1]
UniGeneiMm.53687.

Genome annotation databases

EnsembliENSMUST00000000881; ENSMUSP00000000881; ENSMUSG00000000861. [Q9QYE3-1]
ENSMUST00000109516; ENSMUSP00000105142; ENSMUSG00000000861. [Q9QYE3-13]
ENSMUST00000118955; ENSMUSP00000112948; ENSMUSG00000000861. [Q9QYE3-14]
GeneIDi14025.
KEGGimmu:14025.
UCSCiuc007ifs.2. mouse. [Q9QYE3-15]
uc007ifu.2. mouse. [Q9QYE3-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF051525 mRNA. Translation: AAF22430.1 .
AF169036 mRNA. Translation: AAF65928.1 .
AF169037 mRNA. Translation: AAF65929.1 .
AF186018 mRNA. Translation: AAF63682.1 . Frameshift.
AK004395 mRNA. Translation: BAB23285.1 .
AK043677 mRNA. Translation: BAC31616.1 .
AK045556 mRNA. Translation: BAC32416.1 .
AK049700 mRNA. Translation: BAC33881.1 .
AK122557 mRNA. Translation: BAC65839.1 . Different initiation.
BC010585 mRNA. Translation: AAH10585.1 .
BC051418 mRNA. Translation: AAH51418.1 .
CCDSi CCDS24483.1. [Q9QYE3-1 ]
CCDS48758.1. [Q9QYE3-13 ]
CCDS48759.1. [Q9QYE3-14 ]
PIRi PT0706.
RefSeqi NP_001152761.1. NM_001159289.1.
NP_001152762.1. NM_001159290.1. [Q9QYE3-14 ]
NP_001229863.1. NM_001242934.1.
NP_057916.1. NM_016707.3. [Q9QYE3-1 ]
UniGenei Mm.53687.

3D structure databases

ProteinModelPortali Q9QYE3.
SMRi Q9QYE3. Positions 45-74, 165-202, 379-457.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 199546. 2 interactions.

PTM databases

PhosphoSitei Q9QYE3.

Proteomic databases

MaxQBi Q9QYE3.
PaxDbi Q9QYE3.
PRIDEi Q9QYE3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000000881 ; ENSMUSP00000000881 ; ENSMUSG00000000861 . [Q9QYE3-1 ]
ENSMUST00000109516 ; ENSMUSP00000105142 ; ENSMUSG00000000861 . [Q9QYE3-13 ]
ENSMUST00000118955 ; ENSMUSP00000112948 ; ENSMUSG00000000861 . [Q9QYE3-14 ]
GeneIDi 14025.
KEGGi mmu:14025.
UCSCi uc007ifs.2. mouse. [Q9QYE3-15 ]
uc007ifu.2. mouse. [Q9QYE3-1 ]

Organism-specific databases

CTDi 53335.
MGIi MGI:106190. Bcl11a.
Rougei Search...

Phylogenomic databases

eggNOGi NOG271772.
GeneTreei ENSGT00530000063542.
HOVERGENi HBG050673.
OMAi FRMEAQE.
OrthoDBi EOG7MH0XP.
PhylomeDBi Q9QYE3.
TreeFami TF318131.

Miscellaneous databases

ChiTaRSi BCL11A. mouse.
NextBioi 284944.
PROi Q9QYE3.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q9QYE3.
Bgeei Q9QYE3.
CleanExi MM_BCL11A.
Genevestigatori Q9QYE3.

Family and domain databases

Gene3Di 3.30.160.60. 2 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 3 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product."
    Nakamura T., Yamazaki Y., Saiki Y., Moriyama M., Largaespada D.A., Jenkins N.A., Copeland N.G.
    Mol. Cell. Biol. 20:3178-3186(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3).
    Strain: BXH/2.
  2. "Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors."
    Avram D., Fields A., Pretty On Top K., Nevrivy D.J., Ishmael J.E., Leid M.
    J. Biol. Chem. 275:10315-10322(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INTERACTION WITH TFCOUP1; EAR2 AND ARP1.
    Strain: BALB/c.
    Tissue: Brain.
  3. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4; 5 AND 6).
    Strain: C57BL/6J.
    Tissue: Brain, Brain cortex, Corpora quadrigemina, Embryo and Spinal cord.
  4. "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Aizawa H., Yuasa S., Nakajima D., Nagase T., Ohara O., Koga H.
    DNA Res. 10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 7).
    Tissue: Brain.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 8).
    Strain: FVB/N-3.
    Tissue: Mammary tumor.
  6. Cited for: FUNCTION.
  7. "BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its nuclear body."
    Kuwata T., Nakamura T.
    Genes Cells 13:931-940(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUMOYLATION AT LYS-634, INTERACTION WITH PIAS3, SUBCELLULAR LOCATION, MUTAGENESIS OF LYS-123 AND LYS-637.

Entry informationi

Entry nameiBC11A_MOUSE
AccessioniPrimary (citable) accession number: Q9QYE3
Secondary accession number(s): Q80T89
, Q8BLC7, Q8BLR4, Q8BWX3, Q921V4, Q9D0V2, Q9JIT4, Q9JLK8, Q9JLK9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: May 1, 2000
Last modified: July 9, 2014
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi