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Protein
Submitted name:

Nuclear factor I-C

Gene

Nfic

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 144CTF/NF-IPROSITE-ProRule annotationAdd BLAST144

GO - Molecular functioni

  • core promoter proximal region DNA binding Source: RGD
  • DNA binding Source: RGD
  • double-stranded DNA binding Source: RGD
  • transcription factor activity, sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • DNA replication Source: UniProtKB-UniRule
  • negative regulation of transcription, DNA-templated Source: RGD
  • sensory perception of smell Source: RGD
  • transcription, DNA-templated Source: UniProtKB-UniRule

Keywordsi

Molecular functionActivatorPROSITE-ProRule annotation, DNA-bindingPROSITE-ProRule annotation
Biological processDNA replicationPROSITE-ProRule annotation, Transcription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear factor I-CImported
Gene namesi
Name:NficImported
Synonyms:NFICImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi62016. Nfic.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

  • nucleus Source: RGD

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiQ9QY87.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 144CTF/NF-I DNA-bindingInterPro annotationAdd BLAST144

Sequence similaritiesi

Belongs to the CTF/NF-I family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3663. Eukaryota.
ENOG410Y16G. LUCA.
HOGENOMiHOG000013028.
HOVERGENiHBG006561.
PhylomeDBiQ9QY87.

Family and domain databases

InterProiView protein in InterPro
IPR000647. CTF/NFI.
IPR020604. CTF/NFI_DNA-bd-dom.
IPR019739. CTF/NFI_DNA-bd_CS.
IPR019548. CTF/NFI_DNA-bd_N.
IPR003619. MAD_homology1_Dwarfin-type.
PANTHERiPTHR11492. PTHR11492. 1 hit.
PfamiView protein in Pfam
PF03165. MH1. 1 hit.
PF10524. NfI_DNAbd_pre-N. 1 hit.
SMARTiView protein in SMART
SM00523. DWA. 1 hit.
PROSITEiView protein in PROSITE
PS00349. CTF_NFI_1. 1 hit.
PS51080. CTF_NFI_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9QY87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LLPHVRAFAY TWFNLQARKR KYFKKHEKRM SKDEERAVKD ELLGEKAEVK
60 70 80 90 100
QKWASRLLAK LRKDIRPECR EDFVLAVTGK KAPGCVLSNP DQKGKMRRID
110 120 130 140
CLRQADKVWR LDLVMVILFK GIPLESTDGE RLVKAAASAH PVLC
Length:144
Mass (Da):16,672
Last modified:May 1, 2000 - v1
Checksum:iD23D544A692A70AC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei144Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF112458 mRNA. Translation: AAF23587.1.
UniGeneiRn.86582.

Genome annotation databases

UCSCiRGD:62016. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9QY87_RAT
AccessioniPrimary (citable) accession number: Q9QY87
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: July 5, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)