ID   VAPB_MOUSE              Reviewed;         243 AA.
AC   Q9QY76;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   13-OCT-2009, entry version 60.
DE   RecName: Full=Vesicle-associated membrane protein-associated protein B;
DE            Short=VAMP-associated protein B;
DE            Short=VAMP-B;
DE            Short=VAP-B;
DE   AltName: Full=VAMP-associated protein 33b;
GN   Name=Vapb;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Tang B.L., Low D.L.H., Lock M.L., Hong W.;
RT   "Two forms of mammalian VAP33.";
RL   Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicle trafficking.
CC   -!- SUBUNIT: Homodimer, and heterodimer with VAPA. Interacts with
CC       VAMP1 and VAMP2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type IV membrane
CC       protein (By similarity). Endomembrane system; Single-pass type IV
CC       membrane protein (By similarity). Note=Present in the plasma
CC       membrane and in intracellular vesicles (By similarity).
CC   -!- SIMILARITY: Contains 1 MSP domain.
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DR   EMBL; AF115504; AAF23077.1; -; mRNA.
DR   IPI; IPI00135655; -.
DR   UniGene; Mm.260456; -.
DR   SMR; Q9QY76; 1-134.
DR   STRING; Q9QY76; -.
DR   PhosphoSite; Q9QY76; -.
DR   PRIDE; Q9QY76; -.
DR   Ensembl; ENSMUST00000067530; ENSMUSP00000064699; ENSMUSG00000054455; Mus musculus.
DR   MGI; MGI:1928744; Vapb.
DR   HOGENOM; Q9QY76; -.
DR   HOVERGEN; Q9QY76; -.
DR   ArrayExpress; Q9QY76; -.
DR   Bgee; Q9QY76; -.
DR   Genevestigator; Q9QY76; -.
DR   GermOnline; ENSMUSG00000054455; Mus musculus.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005624; C:membrane fraction; IDA:HGNC.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   InterPro; IPR000535; Major_sperm.
DR   InterPro; IPR008962; PapD-like.
DR   InterPro; IPR016763; Vesicle-associated_membrane.
DR   Gene3D; G3DSA:2.60.40.360; MSP; 1.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   PIRSF; PIRSF019693; VAMP-associated; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cell membrane; Coiled coil; Membrane; Phosphoprotein;
KW   Transmembrane.
FT   INIT_MET      1      1       Removed (By similarity).
FT   CHAIN         2    243       Vesicle-associated membrane protein-
FT                                associated protein B.
FT                                /FTId=PRO_0000213474.
FT   TOPO_DOM      2    218       Cytoplasmic (Potential).
FT   TRANSMEM    219    239       Anchor for type IV membrane protein
FT                                (Potential).
FT   DOMAIN        7    124       MSP.
FT   COILED      161    196       Potential.
FT   MOD_RES       3      3       N6-acetyllysine (By similarity).
FT   MOD_RES     156    156       Phosphoserine (By similarity).
FT   MOD_RES     159    159       Phosphoserine (By similarity).
FT   MOD_RES     206    206       Phosphoserine (By similarity).
SQ   SEQUENCE   243 AA;  26946 MW;  9D88CBC31701C84E CRC64;
     MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTVPR RYCVRPNSGV
     IDAGASLNVS VMLQPFDYDP NEKSKHKFMV QSMFAPPDTS DMEAVWKEAK PEDLMDSKLR
     CVFELPAENA KPHDVEINKI IPTSASKTEA PAAAKSLTSP LDDTEVKKVM EECRRLQGEV
     QRLREESRQL KEEDGLRVRK AMPSNSPVAA LAATGKEEGL SARLLALVVL FFIVGVIIGK
     IAL
//