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Q9QY39

- PDZD4_MOUSE

UniProt

Q9QY39 - PDZD4_MOUSE

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Protein

PDZ domain-containing protein 4

Gene

Pdzd4

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
PDZ domain-containing protein 4
Alternative name(s):
PDZ domain-containing RING finger protein 4-like protein
Gene namesi
Name:Pdzd4
Synonyms:Pdzk4, Pdzrn4l, Xlu
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:2443483. Pdzd4.

Subcellular locationi

Cytoplasmcell cortex By similarity
Note: Mainly localized under the plasma membrane.By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 772772PDZ domain-containing protein 4PRO_0000055922Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei242 – 2421PhosphoserineBy similarity
Modified residuei459 – 4591PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9QY39.
PaxDbiQ9QY39.
PRIDEiQ9QY39.

PTM databases

PhosphoSiteiQ9QY39.

Expressioni

Gene expression databases

BgeeiQ9QY39.
CleanExiMM_PDZD4.
ExpressionAtlasiQ9QY39. baseline and differential.
GenevestigatoriQ9QY39.

Structurei

3D structure databases

ProteinModelPortaliQ9QY39.
SMRiQ9QY39. Positions 14-53, 137-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini136 – 22186PDZPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili394 – 42431Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 1 PDZ (DHR) domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG318730.
GeneTreeiENSGT00510000046421.
HOGENOMiHOG000231379.
HOVERGENiHBG053554.
InParanoidiQ9QY39.
KOiK15682.
OMAiCLREQQN.
OrthoDBiEOG70ZZNP.
PhylomeDBiQ9QY39.
TreeFamiTF315909.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QY39-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGCNMCVVQK PEEQYKVMLQ VNGKELSKLS QEQTLEALRA SKEPLVIQVL
60 70 80 90 100
RRSPRLRGDS SCHDLQLVDS GTQTDITFEH IMALGKLRPP TPPMGILEPY
110 120 130 140 150
VLSELPPISH EYYDPAEFME GGPQEAERMD ELEYEEVELC KNSHQDKLGL
160 170 180 190 200
MVCYRTDEEE DLGIYVGEVN PNSIAAKDGR IREGDRIIQI NGMDVQNREE
210 220 230 240 250
AVAILSQEEN TNISLLVARP ESQLAKRWKD SDRDDFLDDF GSENEGDLRA
260 270 280 290 300
RKLKSPPVQQ IGNDEKGAPD GGPGLNNSQD LDSGVGRTDE STRNEESSEH
310 320 330 340 350
DLLGDEPPST TNTPGSLRKF GLQGDALQSR DFHFSMDSLL AEGAGLGGAD
360 370 380 390 400
LPGLTDEEYE RYRELLEIKC HLENGNQLGI FFSRASSGNS ALDVNRNESL
410 420 430 440 450
GHEMAMLEEE LRHLEFKCRN ILRAQKMQQL RERCMKAWLL EEESLYDLAA
460 470 480 490 500
SEPKKHELSD ISELPEKSDK DSTSAYNTGE SCRSTPLLVE PLPESPLKRS
510 520 530 540 550
GAGNSNLNRT PSGPPVTTHL KGAPSPGSPA KFRSLSRDPE VGRRQHTEER
560 570 580 590 600
VRRSTKTSVT LERVGPEGSP YLSRRHRGQE IEQYHSCVQL APPRTLEDLG
610 620 630 640 650
HGSLSLASGP RVGGVAAAAV EAPRMEWKVK VRSDGTRYVA KRPVRDRLLK
660 670 680 690 700
ARALKIREER SGMTTDDDAV SEMKMGRYWS KEERKQHLIR AREQRKRREF
710 720 730 740 750
MMQSRLECLR EQQNGDSKPE LNIIALSHRK TMKKRNKKIL DNWITIQEML
760 770
AHGARSADGK RIYNPLLSVT TV
Length:772
Mass (Da):86,819
Last modified:February 1, 2005 - v2
Checksum:i1D5A1BA6A6900713
GO

Sequence cautioni

The sequence AAH56462.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF133093 Genomic DNA. No translation available.
AL672094 Genomic DNA. Translation: CAM22462.1.
BC056462 mRNA. Translation: AAH56462.1. Different initiation.
CCDSiCCDS30214.1.
RefSeqiNP_001025039.1. NM_001029868.2.
NP_001277469.1. NM_001290540.1.
UniGeneiMm.103782.

Genome annotation databases

EnsembliENSMUST00000002080; ENSMUSP00000002080; ENSMUSG00000002006.
GeneIDi245469.
KEGGimmu:245469.
UCSCiuc009tmt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF133093 Genomic DNA. No translation available.
AL672094 Genomic DNA. Translation: CAM22462.1 .
BC056462 mRNA. Translation: AAH56462.1 . Different initiation.
CCDSi CCDS30214.1.
RefSeqi NP_001025039.1. NM_001029868.2.
NP_001277469.1. NM_001290540.1.
UniGenei Mm.103782.

3D structure databases

ProteinModelPortali Q9QY39.
SMRi Q9QY39. Positions 14-53, 137-232.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9QY39.

Proteomic databases

MaxQBi Q9QY39.
PaxDbi Q9QY39.
PRIDEi Q9QY39.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000002080 ; ENSMUSP00000002080 ; ENSMUSG00000002006 .
GeneIDi 245469.
KEGGi mmu:245469.
UCSCi uc009tmt.1. mouse.

Organism-specific databases

CTDi 57595.
MGIi MGI:2443483. Pdzd4.

Phylogenomic databases

eggNOGi NOG318730.
GeneTreei ENSGT00510000046421.
HOGENOMi HOG000231379.
HOVERGENi HBG053554.
InParanoidi Q9QY39.
KOi K15682.
OMAi CLREQQN.
OrthoDBi EOG70ZZNP.
PhylomeDBi Q9QY39.
TreeFami TF315909.

Miscellaneous databases

NextBioi 386719.
PROi Q9QY39.
SOURCEi Search...

Gene expression databases

Bgeei Q9QY39.
CleanExi MM_PDZD4.
ExpressionAtlasi Q9QY39. baseline and differential.
Genevestigatori Q9QY39.

Family and domain databases

Gene3Di 2.30.42.10. 1 hit.
InterProi IPR001478. PDZ.
[Graphical view ]
Pfami PF00595. PDZ. 1 hit.
[Graphical view ]
SMARTi SM00228. PDZ. 1 hit.
[Graphical view ]
SUPFAMi SSF50156. SSF50156. 1 hit.
PROSITEi PS50106. PDZ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A., Rosenthal A.
    Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-772.
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiPDZD4_MOUSE
AccessioniPrimary (citable) accession number: Q9QY39
Secondary accession number(s): A2AFG4, Q6PHP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: October 29, 2014
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3