Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

PDZ domain-containing protein 4

Gene

Pdzd4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
PDZ domain-containing protein 4
Alternative name(s):
PDZ domain-containing RING finger protein 4-like protein
Gene namesi
Name:Pdzd4
Synonyms:Pdzk4, Pdzrn4l, Xlu
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2443483. Pdzd4.

Subcellular locationi

  • Cytoplasmcell cortex By similarity

  • Note: Mainly localized under the plasma membrane.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 772772PDZ domain-containing protein 4PRO_0000055922Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei242 – 2421PhosphoserineBy similarity
Modified residuei459 – 4591PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9QY39.
PaxDbiQ9QY39.
PRIDEiQ9QY39.

PTM databases

PhosphoSiteiQ9QY39.

Expressioni

Gene expression databases

BgeeiQ9QY39.
CleanExiMM_PDZD4.
ExpressionAtlasiQ9QY39. baseline and differential.
GenevisibleiQ9QY39. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000002080.

Structurei

3D structure databases

ProteinModelPortaliQ9QY39.
SMRiQ9QY39. Positions 14-52, 137-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini136 – 22186PDZPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili394 – 42431Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 1 PDZ (DHR) domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG318730.
GeneTreeiENSGT00510000046421.
HOGENOMiHOG000231379.
HOVERGENiHBG053554.
InParanoidiQ9QY39.
KOiK15682.
OMAiESEHYHS.
OrthoDBiEOG70ZZNP.
PhylomeDBiQ9QY39.
TreeFamiTF315909.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QY39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCNMCVVQK PEEQYKVMLQ VNGKELSKLS QEQTLEALRA SKEPLVIQVL
60 70 80 90 100
RRSPRLRGDS SCHDLQLVDS GTQTDITFEH IMALGKLRPP TPPMGILEPY
110 120 130 140 150
VLSELPPISH EYYDPAEFME GGPQEAERMD ELEYEEVELC KNSHQDKLGL
160 170 180 190 200
MVCYRTDEEE DLGIYVGEVN PNSIAAKDGR IREGDRIIQI NGMDVQNREE
210 220 230 240 250
AVAILSQEEN TNISLLVARP ESQLAKRWKD SDRDDFLDDF GSENEGDLRA
260 270 280 290 300
RKLKSPPVQQ IGNDEKGAPD GGPGLNNSQD LDSGVGRTDE STRNEESSEH
310 320 330 340 350
DLLGDEPPST TNTPGSLRKF GLQGDALQSR DFHFSMDSLL AEGAGLGGAD
360 370 380 390 400
LPGLTDEEYE RYRELLEIKC HLENGNQLGI FFSRASSGNS ALDVNRNESL
410 420 430 440 450
GHEMAMLEEE LRHLEFKCRN ILRAQKMQQL RERCMKAWLL EEESLYDLAA
460 470 480 490 500
SEPKKHELSD ISELPEKSDK DSTSAYNTGE SCRSTPLLVE PLPESPLKRS
510 520 530 540 550
GAGNSNLNRT PSGPPVTTHL KGAPSPGSPA KFRSLSRDPE VGRRQHTEER
560 570 580 590 600
VRRSTKTSVT LERVGPEGSP YLSRRHRGQE IEQYHSCVQL APPRTLEDLG
610 620 630 640 650
HGSLSLASGP RVGGVAAAAV EAPRMEWKVK VRSDGTRYVA KRPVRDRLLK
660 670 680 690 700
ARALKIREER SGMTTDDDAV SEMKMGRYWS KEERKQHLIR AREQRKRREF
710 720 730 740 750
MMQSRLECLR EQQNGDSKPE LNIIALSHRK TMKKRNKKIL DNWITIQEML
760 770
AHGARSADGK RIYNPLLSVT TV
Length:772
Mass (Da):86,819
Last modified:February 1, 2005 - v2
Checksum:i1D5A1BA6A6900713
GO

Sequence cautioni

The sequence AAH56462.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF133093 Genomic DNA. No translation available.
AL672094 Genomic DNA. Translation: CAM22462.1.
BC056462 mRNA. Translation: AAH56462.1. Different initiation.
CCDSiCCDS30214.1.
RefSeqiNP_001025039.1. NM_001029868.2.
NP_001277469.1. NM_001290540.1.
UniGeneiMm.103782.

Genome annotation databases

EnsembliENSMUST00000002080; ENSMUSP00000002080; ENSMUSG00000002006.
GeneIDi245469.
KEGGimmu:245469.
UCSCiuc009tmt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF133093 Genomic DNA. No translation available.
AL672094 Genomic DNA. Translation: CAM22462.1.
BC056462 mRNA. Translation: AAH56462.1. Different initiation.
CCDSiCCDS30214.1.
RefSeqiNP_001025039.1. NM_001029868.2.
NP_001277469.1. NM_001290540.1.
UniGeneiMm.103782.

3D structure databases

ProteinModelPortaliQ9QY39.
SMRiQ9QY39. Positions 14-52, 137-232.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000002080.

PTM databases

PhosphoSiteiQ9QY39.

Proteomic databases

MaxQBiQ9QY39.
PaxDbiQ9QY39.
PRIDEiQ9QY39.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000002080; ENSMUSP00000002080; ENSMUSG00000002006.
GeneIDi245469.
KEGGimmu:245469.
UCSCiuc009tmt.1. mouse.

Organism-specific databases

CTDi57595.
MGIiMGI:2443483. Pdzd4.

Phylogenomic databases

eggNOGiNOG318730.
GeneTreeiENSGT00510000046421.
HOGENOMiHOG000231379.
HOVERGENiHBG053554.
InParanoidiQ9QY39.
KOiK15682.
OMAiESEHYHS.
OrthoDBiEOG70ZZNP.
PhylomeDBiQ9QY39.
TreeFamiTF315909.

Miscellaneous databases

NextBioi386719.
PROiQ9QY39.
SOURCEiSearch...

Gene expression databases

BgeeiQ9QY39.
CleanExiMM_PDZD4.
ExpressionAtlasiQ9QY39. baseline and differential.
GenevisibleiQ9QY39. MM.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 1 hit.
[Graphical view]
SMARTiSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
PROSITEiPS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A., Rosenthal A.
    Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-772.
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiPDZD4_MOUSE
AccessioniPrimary (citable) accession number: Q9QY39
Secondary accession number(s): A2AFG4, Q6PHP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: July 22, 2015
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.