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Q9QY39 (PDZD4_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
PDZ domain-containing protein 4
Alternative name(s):
PDZ domain-containing RING finger protein 4-like protein
Gene names
Name:Pdzd4
Synonyms:Pdzk4, Pdzrn4l, Xlu
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length772 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Cytoplasmcell cortex By similarity. Note: Mainly localized under the plasma membrane By similarity.

Sequence similarities

Contains 1 PDZ (DHR) domain.

Sequence caution

The sequence AAH56462.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   DomainCoiled coil
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcell cortex

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 772772PDZ domain-containing protein 4
PRO_0000055922

Regions

Domain136 – 22186PDZ
Coiled coil394 – 42431 Potential

Amino acid modifications

Modified residue2421Phosphoserine By similarity
Modified residue4591Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9QY39 [UniParc].

Last modified February 1, 2005. Version 2.
Checksum: 1D5A1BA6A6900713

FASTA77286,819
        10         20         30         40         50         60 
MGCNMCVVQK PEEQYKVMLQ VNGKELSKLS QEQTLEALRA SKEPLVIQVL RRSPRLRGDS 

        70         80         90        100        110        120 
SCHDLQLVDS GTQTDITFEH IMALGKLRPP TPPMGILEPY VLSELPPISH EYYDPAEFME 

       130        140        150        160        170        180 
GGPQEAERMD ELEYEEVELC KNSHQDKLGL MVCYRTDEEE DLGIYVGEVN PNSIAAKDGR 

       190        200        210        220        230        240 
IREGDRIIQI NGMDVQNREE AVAILSQEEN TNISLLVARP ESQLAKRWKD SDRDDFLDDF 

       250        260        270        280        290        300 
GSENEGDLRA RKLKSPPVQQ IGNDEKGAPD GGPGLNNSQD LDSGVGRTDE STRNEESSEH 

       310        320        330        340        350        360 
DLLGDEPPST TNTPGSLRKF GLQGDALQSR DFHFSMDSLL AEGAGLGGAD LPGLTDEEYE 

       370        380        390        400        410        420 
RYRELLEIKC HLENGNQLGI FFSRASSGNS ALDVNRNESL GHEMAMLEEE LRHLEFKCRN 

       430        440        450        460        470        480 
ILRAQKMQQL RERCMKAWLL EEESLYDLAA SEPKKHELSD ISELPEKSDK DSTSAYNTGE 

       490        500        510        520        530        540 
SCRSTPLLVE PLPESPLKRS GAGNSNLNRT PSGPPVTTHL KGAPSPGSPA KFRSLSRDPE 

       550        560        570        580        590        600 
VGRRQHTEER VRRSTKTSVT LERVGPEGSP YLSRRHRGQE IEQYHSCVQL APPRTLEDLG 

       610        620        630        640        650        660 
HGSLSLASGP RVGGVAAAAV EAPRMEWKVK VRSDGTRYVA KRPVRDRLLK ARALKIREER 

       670        680        690        700        710        720 
SGMTTDDDAV SEMKMGRYWS KEERKQHLIR AREQRKRREF MMQSRLECLR EQQNGDSKPE 

       730        740        750        760        770 
LNIIALSHRK TMKKRNKKIL DNWITIQEML AHGARSADGK RIYNPLLSVT TV 

« Hide

References

[1]Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A., Rosenthal A.
Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-772.
Strain: C57BL/6.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF133093 Genomic DNA. No translation available.
AL672094 Genomic DNA. Translation: CAM22462.1.
BC056462 mRNA. Translation: AAH56462.1. Different initiation.
CCDSCCDS30214.1.
RefSeqNP_001025039.1. NM_001029868.2.
NP_001277469.1. NM_001290540.1.
UniGeneMm.103782.

3D structure databases

ProteinModelPortalQ9QY39.
SMRQ9QY39. Positions 14-53, 137-232.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9QY39.

Proteomic databases

PaxDbQ9QY39.
PRIDEQ9QY39.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000002080; ENSMUSP00000002080; ENSMUSG00000002006.
GeneID245469.
KEGGmmu:245469.
UCSCuc009tmt.1. mouse.

Organism-specific databases

CTD57595.
MGIMGI:2443483. Pdzd4.

Phylogenomic databases

eggNOGNOG318730.
GeneTreeENSGT00510000046421.
HOGENOMHOG000231379.
HOVERGENHBG053554.
InParanoidA2AFG4.
KOK15682.
OMACLREQQN.
OrthoDBEOG70ZZNP.
PhylomeDBQ9QY39.
TreeFamTF315909.

Gene expression databases

ArrayExpressQ9QY39.
BgeeQ9QY39.
CleanExMM_PDZD4.
GenevestigatorQ9QY39.

Family and domain databases

Gene3D2.30.42.10. 1 hit.
InterProIPR001478. PDZ.
[Graphical view]
PfamPF00595. PDZ. 1 hit.
[Graphical view]
SMARTSM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMSSF50156. SSF50156. 1 hit.
PROSITEPS50106. PDZ. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio386719.
PROQ9QY39.
SOURCESearch...

Entry information

Entry namePDZD4_MOUSE
AccessionPrimary (citable) accession number: Q9QY39
Secondary accession number(s): A2AFG4, Q6PHP2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: February 1, 2005
Last modified: July 9, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot