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Q9QY39

- PDZD4_MOUSE

UniProt

Q9QY39 - PDZD4_MOUSE

Protein

PDZ domain-containing protein 4

Gene

Pdzd4

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 2 (01 Feb 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    PDZ domain-containing protein 4
    Alternative name(s):
    PDZ domain-containing RING finger protein 4-like protein
    Gene namesi
    Name:Pdzd4
    Synonyms:Pdzk4, Pdzrn4l, Xlu
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome X

    Organism-specific databases

    MGIiMGI:2443483. Pdzd4.

    Subcellular locationi

    Cytoplasmcell cortex By similarity
    Note: Mainly localized under the plasma membrane.By similarity

    GO - Cellular componenti

    1. cell cortex Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 772772PDZ domain-containing protein 4PRO_0000055922Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei242 – 2421PhosphoserineBy similarity
    Modified residuei459 – 4591PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ9QY39.
    PRIDEiQ9QY39.

    PTM databases

    PhosphoSiteiQ9QY39.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9QY39.
    BgeeiQ9QY39.
    CleanExiMM_PDZD4.
    GenevestigatoriQ9QY39.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9QY39.
    SMRiQ9QY39. Positions 14-53, 137-232.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini136 – 22186PDZPROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili394 – 42431Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PDZ (DHR) domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG318730.
    GeneTreeiENSGT00510000046421.
    HOGENOMiHOG000231379.
    HOVERGENiHBG053554.
    InParanoidiA2AFG4.
    KOiK15682.
    OMAiCLREQQN.
    OrthoDBiEOG70ZZNP.
    PhylomeDBiQ9QY39.
    TreeFamiTF315909.

    Family and domain databases

    Gene3Di2.30.42.10. 1 hit.
    InterProiIPR001478. PDZ.
    [Graphical view]
    PfamiPF00595. PDZ. 1 hit.
    [Graphical view]
    SMARTiSM00228. PDZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF50156. SSF50156. 1 hit.
    PROSITEiPS50106. PDZ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9QY39-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGCNMCVVQK PEEQYKVMLQ VNGKELSKLS QEQTLEALRA SKEPLVIQVL    50
    RRSPRLRGDS SCHDLQLVDS GTQTDITFEH IMALGKLRPP TPPMGILEPY 100
    VLSELPPISH EYYDPAEFME GGPQEAERMD ELEYEEVELC KNSHQDKLGL 150
    MVCYRTDEEE DLGIYVGEVN PNSIAAKDGR IREGDRIIQI NGMDVQNREE 200
    AVAILSQEEN TNISLLVARP ESQLAKRWKD SDRDDFLDDF GSENEGDLRA 250
    RKLKSPPVQQ IGNDEKGAPD GGPGLNNSQD LDSGVGRTDE STRNEESSEH 300
    DLLGDEPPST TNTPGSLRKF GLQGDALQSR DFHFSMDSLL AEGAGLGGAD 350
    LPGLTDEEYE RYRELLEIKC HLENGNQLGI FFSRASSGNS ALDVNRNESL 400
    GHEMAMLEEE LRHLEFKCRN ILRAQKMQQL RERCMKAWLL EEESLYDLAA 450
    SEPKKHELSD ISELPEKSDK DSTSAYNTGE SCRSTPLLVE PLPESPLKRS 500
    GAGNSNLNRT PSGPPVTTHL KGAPSPGSPA KFRSLSRDPE VGRRQHTEER 550
    VRRSTKTSVT LERVGPEGSP YLSRRHRGQE IEQYHSCVQL APPRTLEDLG 600
    HGSLSLASGP RVGGVAAAAV EAPRMEWKVK VRSDGTRYVA KRPVRDRLLK 650
    ARALKIREER SGMTTDDDAV SEMKMGRYWS KEERKQHLIR AREQRKRREF 700
    MMQSRLECLR EQQNGDSKPE LNIIALSHRK TMKKRNKKIL DNWITIQEML 750
    AHGARSADGK RIYNPLLSVT TV 772
    Length:772
    Mass (Da):86,819
    Last modified:February 1, 2005 - v2
    Checksum:i1D5A1BA6A6900713
    GO

    Sequence cautioni

    The sequence AAH56462.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF133093 Genomic DNA. No translation available.
    AL672094 Genomic DNA. Translation: CAM22462.1.
    BC056462 mRNA. Translation: AAH56462.1. Different initiation.
    CCDSiCCDS30214.1.
    RefSeqiNP_001025039.1. NM_001029868.2.
    NP_001277469.1. NM_001290540.1.
    UniGeneiMm.103782.

    Genome annotation databases

    EnsembliENSMUST00000002080; ENSMUSP00000002080; ENSMUSG00000002006.
    GeneIDi245469.
    KEGGimmu:245469.
    UCSCiuc009tmt.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF133093 Genomic DNA. No translation available.
    AL672094 Genomic DNA. Translation: CAM22462.1 .
    BC056462 mRNA. Translation: AAH56462.1 . Different initiation.
    CCDSi CCDS30214.1.
    RefSeqi NP_001025039.1. NM_001029868.2.
    NP_001277469.1. NM_001290540.1.
    UniGenei Mm.103782.

    3D structure databases

    ProteinModelPortali Q9QY39.
    SMRi Q9QY39. Positions 14-53, 137-232.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9QY39.

    Proteomic databases

    PaxDbi Q9QY39.
    PRIDEi Q9QY39.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000002080 ; ENSMUSP00000002080 ; ENSMUSG00000002006 .
    GeneIDi 245469.
    KEGGi mmu:245469.
    UCSCi uc009tmt.1. mouse.

    Organism-specific databases

    CTDi 57595.
    MGIi MGI:2443483. Pdzd4.

    Phylogenomic databases

    eggNOGi NOG318730.
    GeneTreei ENSGT00510000046421.
    HOGENOMi HOG000231379.
    HOVERGENi HBG053554.
    InParanoidi A2AFG4.
    KOi K15682.
    OMAi CLREQQN.
    OrthoDBi EOG70ZZNP.
    PhylomeDBi Q9QY39.
    TreeFami TF315909.

    Miscellaneous databases

    NextBioi 386719.
    PROi Q9QY39.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9QY39.
    Bgeei Q9QY39.
    CleanExi MM_PDZD4.
    Genevestigatori Q9QY39.

    Family and domain databases

    Gene3Di 2.30.42.10. 1 hit.
    InterProi IPR001478. PDZ.
    [Graphical view ]
    Pfami PF00595. PDZ. 1 hit.
    [Graphical view ]
    SMARTi SM00228. PDZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50156. SSF50156. 1 hit.
    PROSITEi PS50106. PDZ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A., Rosenthal A.
      Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 10-772.
      Strain: C57BL/6.
      Tissue: Brain.

    Entry informationi

    Entry nameiPDZD4_MOUSE
    AccessioniPrimary (citable) accession number: Q9QY39
    Secondary accession number(s): A2AFG4, Q6PHP2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 2005
    Last sequence update: February 1, 2005
    Last modified: October 1, 2014
    This is version 85 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3