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Q9QXY8 (CCL7_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
C-C motif chemokine 7
Alternative name(s):
Monocyte chemoattractant protein 3
Monocyte chemotactic protein 3
Short name=MCP-3
Small-inducible cytokine A7
Gene names
Name:Ccl7
Synonyms:Mcp3, Scya7
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length97 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity By similarity.

Subunit structure

Monomer By similarity.

Subcellular location

Secreted.

Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 9774C-C motif chemokine 7
PRO_0000005185

Amino acid modifications

Modified residue241Pyrrolidone carboxylic acid By similarity
Glycosylation291N-linked (GlcNAc...) Potential
Disulfide bond33 ↔ 57 By similarity
Disulfide bond34 ↔ 73 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9QXY8 [UniParc].

Last modified May 1, 2000. Version 1.
Checksum: AEDBB7BD9288F0C4

FASTA9710,906
        10         20         30         40         50         60 
MQISAALLCV LLTAAAFTVH VWAQPDGTNS STCCYVKKQK IPKRNLKSYR KITSSRCPWE 

        70         80         90 
AVIFKTKKGM EVCAEAHQKW VEEAIAYLDM KTSTPKP 

« Hide

References

[1]"Molecular cloning and expression of the rat monocyte chemotactic protein-3 gene: a possible role in stroke."
Wang X., Li X., Yaish-Ohad S., Sarau H.M., Barone F.C., Feuerstein G.Z.
Brain Res. Mol. Brain Res. 71:304-312(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF154245 Genomic DNA. Translation: AAF24172.1.
RefSeqNP_001007613.1. NM_001007612.1.
UniGeneRn.26815.

3D structure databases

ProteinModelPortalQ9QXY8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000000256.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000000256; ENSRNOP00000000256; ENSRNOG00000000239.
GeneID287561.
KEGGrno:287561.

Organism-specific databases

CTD6354.
RGD1359152. Ccl7.

Phylogenomic databases

eggNOGNOG140372.
GeneTreeENSGT00730000110714.
HOGENOMHOG000036686.
HOVERGENHBG017871.
InParanoidQ9QXY8.
KOK05509.
OMAGDMNSAS.
OrthoDBEOG7673DP.
PhylomeDBQ9QXY8.
TreeFamTF334888.

Gene expression databases

GenevestigatorQ9QXY8.

Family and domain databases

InterProIPR000827. Chemokine_CC_CS.
IPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamPF00048. IL8. 1 hit.
[Graphical view]
SMARTSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMSSF54117. SSF54117. 1 hit.
PROSITEPS00472. SMALL_CYTOKINES_CC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio626523.
PROQ9QXY8.

Entry information

Entry nameCCL7_RAT
AccessionPrimary (citable) accession number: Q9QXY8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 2000
Last modified: May 14, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families