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Protein

Surfeit locus protein 1

Gene

Surf1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Surfeit locus protein 1
Gene namesi
Name:Surf1
Synonyms:Surf-1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi620527. Surf1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei68 – 86HelicalSequence analysisAdd BLAST19
Transmembranei280 – 300HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002156541 – 306Surfeit locus protein 1Add BLAST306

Proteomic databases

PaxDbiQ9QXU2.
PRIDEiQ9QXU2.

PTM databases

iPTMnetiQ9QXU2.
PhosphoSitePlusiQ9QXU2.

Expressioni

Gene expression databases

BgeeiENSRNOG00000005247.
GenevisibleiQ9QXU2. RN.

Interactioni

Subunit structurei

Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, the core components of this complex being COA3/MITRAC12 and COX14. Interacts with COA3.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006855.

Family & Domainsi

Sequence similaritiesi

Belongs to the SURF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410KDF7. Eukaryota.
COG3346. LUCA.
GeneTreeiENSGT00530000064194.
HOGENOMiHOG000097776.
HOVERGENiHBG058486.
InParanoidiQ9QXU2.
KOiK14998.
OrthoDBiEOG091G0IWR.

Family and domain databases

CDDicd06662. SURF1. 1 hit.
InterProiView protein in InterPro
IPR002994. Surf1/Shy1.
PfamiView protein in Pfam
PF02104. SURF1. 1 hit.
PROSITEiView protein in PROSITE
PS50895. SURF1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9QXU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVMALTVL RSRITRWPQW ACAGPAPFCA VRRSVFGFSV RSGMVCRPHR
60 70 80 90 100
CCSSTAETAA AKAEDDSFLQ WFLLFIPATA FGLGTWQVQR RKWKLKLIAE
110 120 130 140 150
LESRVMAEPI PLPADPMELK NLEYRPVKVR GHFDHSKELY IMPRTMVDPV
160 170 180 190 200
REARDAGRLS STESGAYVVT PFHCSDLGVT ILVNRGFVPR KKVNPETRQQ
210 220 230 240 250
GQVLGEVDLV GIVRLTENRK PFVPENNPER SLWYYRDLDA MAKRTGTDPI
260 270 280 290 300
FIDADFNSTT PGGPIGGQTR VTLRNEHMQY IITWYGLCAA TSYLWFRKFV

RRTPGV
Length:306
Mass (Da):34,683
Last modified:May 1, 2000 - v1
Checksum:i2CB7E4F5B8A94850
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF182952 mRNA. Translation: AAF19608.1.
RefSeqiNP_742065.1. NM_172068.1.
XP_006233790.1. XM_006233728.3.
UniGeneiRn.74313.

Genome annotation databases

EnsembliENSRNOT00000061242; ENSRNOP00000057954; ENSRNOG00000005247.
GeneIDi100912008.
64463.
KEGGirno:100912008.
rno:64463.
UCSCiRGD:620527. rat.

Similar proteinsi

Entry informationi

Entry nameiSURF1_RAT
AccessioniPrimary (citable) accession number: Q9QXU2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: August 30, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families