Unreviewed, UniProtKB/TrEMBL Q9QXN6 (Q9QXN6_MOUSE)

Names and origin

Protein names

Submitted name:
    Interleukin-2 EMBL AAF22748.1

Gene names

Name:

Il2 MGI 96548

Organism

Mus musculus (Mouse) EMBL AAF22748.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	11 AA.
Sequence status	Fragment.
Protein existence	Predicted.

Ontologies

Gene Ontology (GO)
Biological process	negative regulation of inflammatory response Inferred from mutant phenotype. Source: MGI negative regulation of lymphocyte proliferation Inferred from mutant phenotype. Source: MGI positive regulation of activated T cell proliferation Inferred from direct assay. Source: MGI positive regulation of immunoglobulin secretion Inferred from mutant phenotype. Source: MGI positive regulation of isotype switching to IgG isotypes Inferred from mutant phenotype. Source: MGI positive regulation of transcription from RNA polymerase II promoter Inferred from direct assay. Source: MGI positive regulation of tyrosine phosphorylation of Stat5 protein Inferred from direct assay. Source: MGI regulation of T cell homeostatic proliferation Inferred from mutant phenotype. Source: MGI
Cellular component	extracellular space Inferred from direct assay. Source: MGI
Molecular function	cytokine activity Inferred from direct assay. Source: MGI interleukin-2 receptor binding Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	11	1	EMBL AAF22748.1

Sequences

	Sequence		Length	Mass (Da)
	Q9QXN6-1 [UniParc]. Last modified May 1, 2000. Version 1. Checksum: AE23EC9CBDD736D6	FASTA	11	1,233
	10 MYSMQLASCV T

References

[1]

"Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping." Lyons P.A., Armitage N., Argentina F., Denny P., Hill N.J., Lord C.J., Wilusz M.B., Peterson L.B., Wicker L.S., Todd J.A. Genome Res. 10:446-453(2000) [PubMed: 10779485] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 129 EMBL AAF22748.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF195955 Genomic DNA. Translation: AAF22748.1.
IPI	IPI00115183.
UniGene	Mm.14190
3D structure databases
ModBase	Search...
Organism-specific databases
MGI	MGI:96548. Il2.
Phylogenomic databases
HOVERGEN	Q9QXN6.
Gene expression databases
Genevestigator	Q9QXN6.
Family and domain databases
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q9QXN6_MOUSE

Accession

Primary (citable) accession number: Q9QXN6

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 2000
Last sequence update:	May 1, 2000
Last modified:	February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)