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Protein
Submitted name:

CYP2J4

Gene

Cyp2j4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • arachidonic acid metabolic process Source: RGD
  • female pregnancy Source: RGD
  • response to organic cyclic compound Source: RGD
  • retinoid metabolic process Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
CYP2J4Imported
Gene namesi
Name:Cyp2j4Imported
Synonyms:CYP2J4Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620007. Cyp2j4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • intracellular membrane-bounded organelle Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9QXF7.
PRIDEiQ9QXF7.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012977.

Structurei

3D structure databases

ProteinModelPortaliQ9QXF7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG015789.
PhylomeDBiQ9QXF7.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008071. Cyt_P450_E_grp-I_CYP2J-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01688. EP450ICYP2J.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9QXF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLATAGSLIA TIWAALHLRT LLVAALTFLL LADYFKTRRP KNYPPGPWGL
60 70 80 90 100
PFVGNIFQLD FGQPHLSIQP FVKKYGNIFS LNLGDITSVV ITGLPLIKET
110 120 130 140 150
FTHIEQNILN RPLSVMQERI TNKNGLIFSS GQTWKEQRRF ALMTLRNFGL
160 170 180 190 200
GKKSLEQRMQ EEAHYLVEAI REEKGKPFNP HFSINNAVSN IICSVTFGER
210 220 230 240 250
FEYHDSRFQE MLRLLDEVMY LETTMISQLY NIFPWIMKYI PGSHQTVFRN
260 270 280 290 300
WEKLKLFVSS MIDDHRKDWN PEEPRDFIDA FLKEMSKYPE KTTSFNEENL
310 320 330 340 350
ICSTLDLFFA GTETTSTTLR WALLYMALYP EVQEKVQAEI DRVIGQKRAA
360 370 380 390 400
SLADRESMPY TNAVIHEVQR MGNIIPLNVP REVAMDTTLN GFHLPKGTMV
410 420 430 440 450
LTNLTALHRD PKEWATPDVF NPEHFLENGQ FKKRESFLPF SMGKRACLGE
460 470 480 490 500
QLARSELFIF FTSLMQKFTF KPPTNEKLSL KFRNGLTLSP VTHRICAVPR

E
Length:501
Mass (Da):57,878
Last modified:May 1, 2000 - v1
Checksum:iE109044023024DCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L81170 mRNA. Translation: AAF21133.1.
UniGeneiRn.44992.

Genome annotation databases

UCSCiRGD:620007. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L81170 mRNA. Translation: AAF21133.1.
UniGeneiRn.44992.

3D structure databases

ProteinModelPortaliQ9QXF7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012977.

Proteomic databases

PaxDbiQ9QXF7.
PRIDEiQ9QXF7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:620007. rat.

Organism-specific databases

RGDi620007. Cyp2j4.

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
HOVERGENiHBG015789.
PhylomeDBiQ9QXF7.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
IPR008071. Cyt_P450_E_grp-I_CYP2J-like.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR01688. EP450ICYP2J.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9QXF7_RAT
AccessioniPrimary (citable) accession number: Q9QXF7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 2000
Last sequence update: May 1, 2000
Last modified: May 11, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.